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Scientific Publications

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Small-molecule screens

  • J.P. von Kries
/ Cancer Lett

Proteasome inhibitors suppress MYB oncogenic activity in a p300-dependent manner

  • M.V. Yusenko
  • A. Biyanee
  • M.K. Andersson
  • S. Radetzki
  • J.P. von Kries
  • G. Stenman
  • K.H. Klempnauer
/ Nat Med

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase

  • D.A. Ruess
  • G.J. Heynen
  • K.J. Ciecielski
  • J. Ai
  • A. Berninger
  • D. Kabacaoglu
  • K. Görgülü
  • Z. Dantes
  • S.M. Wörmann
  • K.N. Diakopoulos
  • A.F. Karpathaki
  • M. Kowalska
  • E. Kaya-Aksoy
  • L. Song
  • E.A. Zeeuw van der Laan
  • M.P. López-Alberca
  • M. Nazaré
  • M. Reichert
  • D. Saur
  • M.M. Erkan
  • U.T. Hopt
  • B. Sainz
  • W. Birchmeier
  • R.M. Schmid
  • M. Lesina
  • H. Algül
/ J Med Chem

Discovery of a novel series of tankyrase inhibitors by a hybridization approach

  • U.R. Anumala
  • J. Waaler
  • Y. Nkizinkiko
  • A. Ignatev
  • K. Lazarow
  • P. Lindemann
  • P.A. Olsen
  • S. Murthy
  • E. Obaji
  • A.G. Majouga
  • S. Leonov
  • J.P. von Kries
  • L. Lehtiö
  • S. Krauss
  • M. Nazaré
/ PLoS ONE

Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling

  • M. Liss
  • M.H. Radke
  • J. Eckhard
  • M. Neuenschwander
  • V. Dauksaite
  • J.P. von Kries
  • M. Gotthardt
/ Cell Microbiol

Keratinocyte-specific ablation of protease-activated receptor-2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease

  • N. Francis
  • B.A. Ayodele
  • N.M. O'Brien-Simpson
  • W. Birchmeier
  • R.N. Pike
  • C.N. Pagel
  • E.J. Mackie
/ Nat Commun

The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis

  • A. Zehender
  • J. Huang
  • A.H. Györfi
  • A.E. Matei
  • T. Trinh-Minh
  • X. Xu
  • Y.N. Li
  • C.W. Chen
  • J. Lin
  • C. Dees
  • C. Beyer
  • K. Gelse
  • Z.Y. Zhang
  • C. Bergmann
  • A. Ramming
  • W. Birchmeier
  • O. Distler
  • G. Schett
  • J.H.W. Distler
/ ChemBioChem

DMACM-caged adenosine nucleotides: Ultrafast phototriggers for ATP, ADR and AMP activated by long-wavelength irradiation

  • D. Geissler
  • W. Kresse
  • B. Wiesner
  • J. Bendig
  • H. Kettenmann
  • V. Hagen
/ Neuron

Neuronal or glial progeny: Regional differences in radial glia fate

  • P. Malatesta
  • M.A. Hack
  • E. Hartfuss
  • H. Kettenmann
  • W. Klinkert
  • F. Kirchhoff
  • M. Goetz
/ J Neurosci

Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus

  • K. Matthias
  • F. Kirchhoff
  • G. Seifert
  • K. Huettmann
  • M. Matyash
  • H. Kettenmann
  • C. Steinhaeuser