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Scientific Publications

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in Cell Rep

USP15 deubiquitinase safeguards hematopoiesis and genome integrity in hematopoietic stem cells and leukemia cells

  • P. van den Berk
  • C. Lancini
  • C. Company
  • M. Serresi
  • M.P. Sanchez-Bailon
  • D. Hulsman
  • C. Pritchard
  • J.Y. Song
  • M.J. Schmitt
  • E. Tanger
  • O. Popp
  • P. Mertins
  • I.J. Huijbers
  • H. Jacobs
  • M. van Lohuizen
  • G. Gargiulo
  • E. Citterio
in Cancer Discov

Phenotypic mapping of pathological crosstalk between glioblastoma and innate immune cells by synthetic genetic tracing

  • M.J. Schmitt
  • C. Company
  • Y. Dramaretska
  • I. Barozzi
  • A. Göhrig
  • S. Kertalli
  • M. Großmann
  • H. Naumann
  • M.P. Sanchez-Bailon
  • D. Hulsman
  • R. Glass
  • M. Squatrito
  • M. Serresi
  • G. Gargiulo
in Nat Commun

The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness

  • J. Grinat
  • J. Heuberger
  • R. Vidal
  • N. Goveas
  • F. Kosel
  • A. Berenguer-Llergo
  • A. Kranz
  • A. Wulf-Goldenberg
  • D. Behrens
  • B. Melcher
  • S. Sauer
  • M. Vieth
  • E. Batlle
  • A. Stewart
  • W. Birchmeier
in J Med Chem

From pyrazolones to azaindoles: evolution of active-site SHP2 inhibitors based on scaffold hopping and bioisosteric replacement

  • Y. Mostinski
  • G.J.J.E. Heynen
  • M.P. López-Alberca
  • J. Paul
  • S. Miksche
  • S. Radetzki
  • D. Schaller
  • E. Shanina
  • C. Seyffarth
  • Y. Kolomeets
  • N. Ziebart
  • J. de Schryver
  • S. Oestreich
  • M. Neuenschwander
  • Y. Roske
  • U. Heinemann
  • C. Rademacher
  • A. Volkamer
  • J.P. von Kries
  • W. Birchmeier
  • M. Nazaré
in Cell Rep

Interactome mapping provides a network of neurodegenerative disease proteins and uncovers widespread protein aggregation in affected brains

  • C. Haenig
  • N. Atias
  • A.K. Taylor
  • A. Mazza
  • M.H. Schaefer
  • J. Russ
  • S.P. Riechers
  • S. Jain
  • M. Coughlin
  • J.F. Fontaine
  • B.D. Freibaum
  • L. Brusendorf
  • M. Zenkner
  • P. Porras
  • M. Stroedicke
  • S. Schnoegl
  • K. Arnsburg
  • A. Boeddrich
  • L. Pigazzini
  • P. Heutink
  • J.P. Taylor
  • J. Kirstein
  • M.A. Andrade-Navarro
  • R. Sharan
  • E.E. Wanker
in J Mol Biol

Sclerotiorin stabilizes the assembly of nonfibrillar Abeta42 oligomers with low toxicity, seeding activity, and beta-sheet content

  • T. Wiglenda
  • N. Groenke
  • W. Hoffmann
  • C. Manz
  • L. Diez
  • A. Buntru
  • L. Brusendorf
  • N. Neuendorf
  • S. Schnoegl
  • C. Haenig
  • P. Schmieder
  • K. Pagel
  • E.E. Wanker
in Nat Commun

Tracing tumorigenesis in a solid tumor model at single-cell resolution

  • S.D. Praktiknjo
  • B. Obermayer
  • Q. Zhu
  • L. Fang
  • H. Liu
  • H. Quinn
  • M. Stoeckius
  • C. Kocks
  • W. Birchmeier
  • N. Rajewsky
in Nat Commun

Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients

  • A. Fendler
  • D. Bauer
  • J. Busch
  • K. Jung
  • A. Wulf-Goldenberg
  • S. Kunz
  • K. Song
  • A. Myszczyszyn
  • S. Elezkurtaj
  • B. Erguen
  • S. Jung
  • W. Chen
  • W. Birchmeier
in Brain

Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain

  • J. Van Steenwinckel
  • A.L. Schang
  • M.L. Krishnan
  • V. Degos
  • A. Delahaye-Duriez
  • C. Bokobza
  • Z. Csaba
  • F. Verdonk
  • A. Montané
  • S. Sigaut
  • O. Hennebert
  • S. Lebon
  • L. Schwendimann
  • T. Le Charpentier
  • R. Hassan-Abdi
  • G. Ball
  • P. Aljabar
  • A. Saxena
  • R.K. Holloway
  • W. Birchmeier
  • O. Baud
  • D. Rowitch
  • V. Miron
  • F. Chretien
  • C. Leconte
  • V.C. Besson
  • E.G. Petretto
  • A.D. Edwards
  • H. Hagberg
  • N. Soussi-Yanicostas
  • B. Fleiss
  • P. Gressens
in Front Immunol

SHP-2 in lymphocytes' cytokine and inhibitory receptor signaling

  • C. Niogret
  • W. Birchmeier
  • G. Guarda