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Scientific Publications

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/ Mol Syst Biol

AI-guided pipeline for protein-protein interaction drug discovery identifies an SARS-CoV-2 inhibitor

  • P. Trepte
  • C. Secker
  • J. Olivet
  • J. Blavier
  • S. Kostova
  • S.B. Maseko
  • I. Minia
  • E. Silva Ramos
  • P. Cassonnet
  • S. Golusik
  • M. Zenkner
  • S. Beetz
  • M.J. Liebich
  • N. Scharek
  • A. Schutz
  • M. Sperling
  • M. Lisurek
  • Y. Wang
  • K. Spirohn
  • T. Hao
  • M.A. Calderwood
  • D.E. Hill
  • M. Landthaler
  • S.G. Choi
  • J.C. Twizere
  • M. Vidal
  • E.E. Wanker
/ Cancers

Immune response and metastasis-links between the metastasis driver MACC1 and cancer immune escape strategies

  • S. Torke
  • W. Walther
  • U. Stein
/ FEBS Lett

EU-LIFE charter of independent life science research institutes

  • G. Superti-Furga
  • M. Agostinho
  • J. Bury
  • S. Cook
  • C. Durinx
  • A. Ender
  • H. van Luenen
  • A.H. Lund
  • R.H. Medema
  • M. Miączyńska
  • D. Nickel
  • P.G. Pelicci
  • A. Puisieux
  • S. Ripatti
  • M. Sander
  • D. Schubeler
  • L. Serrano
  • T. Sommer
  • K. Sonne-Hansen
  • P. Tomančák
  • J. Vives
  • J. Vontas
  • M. Bettencourt-Dias
/ Nucleic Acids Res

Despite the odds: formation of the SARS-CoV-2 methylation complex

  • A. Matsuda
  • J. Plewka
  • M. Rawski
  • A. Mourão
  • W. Zajko
  • T. Siebenmorgen
  • L. Kresik
  • K. Lis
  • A.N. Jones
  • M. Pachota
  • A. Karim
  • K. Hartman
  • S. Nirwal
  • R. Sonani
  • Y. Chykunova
  • I. Minia
  • P. Mak
  • M. Landthaler
  • M. Nowotny
  • G. Dubin
  • M. Sattler
  • P. Suder
  • G.M. Popowicz
  • K. Pyrć
  • A. Czarna
/ Nat Neurosci

Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early- and late-phase COVID-19

  • J. Radke
  • J. Meinhardt
  • T. Aschman
  • R.L. Chua
  • V. Farztdinov
  • S. Lukassen
  • F.W. Ten
  • E. Friebel
  • N. Ishaque
  • J. Franz
  • V.H. Huhle
  • R. Mothes
  • K. Peters
  • C. Thomas
  • S. Schneeberger
  • E. Schumann
  • L. Kawelke
  • J. Jünger
  • V. Horst
  • S. Streit
  • R. von Manitius
  • P. Körtvélyessy
  • S. Vielhaber
  • D. Reinhold
  • A.E. Hauser
  • A. Osterloh
  • P. Enghard
  • J. Ihlow
  • S. Elezkurtaj
  • D. Horst
  • F. Kurth
  • M.A. Müller
  • N.C. Gassen
  • J. Melchert
  • K. Jechow
  • B. Timmermann
  • C. Fernandez-Zapata
  • C. Böttcher
  • W. Stenzel
  • E. Krüger
  • M. Landthaler
  • E. Wyler
  • V. Corman
  • C. Stadelmann
  • M. Ralser
  • R. Eils
  • F.L. Heppner
  • M. Mülleder
  • C. Conrad
  • H. Radbruch
/ BMJ Open Respir Res

Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters

  • L.G. Teixeira Alves
  • M. Baumgardt
  • C. Langner
  • M. Fischer
  • J. Maria Adler
  • J. Bushe
  • T.C. Firsching
  • G. Mastrobuoni
  • J. Grobe
  • K. Hoenzke
  • S. Kempa
  • A.D. Gruber
  • A.C. Hocke
  • J. Trimpert
  • E. Wyler
  • M. Landthaler
/ mBio

Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection

  • G. Sun
  • K.A. Kropp
  • M. Kirchner
  • N. Plückebaum
  • A. Selich
  • M. Serrero
  • A. Dhingra
  • J.R. Cabrera
  • B. Ritter
  • R. Bauerfeind
  • E. Wyler
  • M. Landthaler
  • A. Schambach
  • B. Sodeik
  • P. Mertins
  • A. Viejo-Borbolla
/ Cancers

MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer

  • M. Erdem
  • K.H. Lee
  • M. Hardt
  • J.L. Regan
  • D. Kobelt
  • W. Walther
  • M. Mokrizkij
  • C. Regenbrecht
  • U. Stein
/ Blood

Regulation of lymphoid-myeloid lineage bias through Regnase-1/3-mediated control of Nfkbiz

  • T. Uehata
  • S. Yamada
  • D. Ori
  • A. Vandenbon
  • A. Giladi
  • A. Jelinski
  • Y. Murakawa
  • H. Watanabe
  • K. Takeuchi
  • K. Toratani
  • T. Mino
  • H. Kiryu
  • D.M. Standley
  • T. Tsujimura
  • T. Ikawa
  • G. Kondoh
  • M. Landthaler
  • H. Kawamoto
  • H.R. Rodewald
  • I. Amit
  • R. Yamamoto
  • M. Miyazaki
  • O. Takeuchi
/ Nucleic Acids Res

Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation

  • Y. Roske
  • C. Cappel
  • N. Cremer
  • P. Hoffmann
  • T. Koudelka
  • A. Tholey
  • U. Heinemann
  • O. Daumke
  • M. Damme