Scientific Publications | Max Delbrück Center

140 Results:

October 01, 2021 / Bioinformatics

GAMIBHEAR: whole-genome haplotype reconstruction from Genome Architecture Mapping data

J. Markowski
R. Kempfer
A. Kukalev
I. Irastorza-Azcarate
G. Loof
B. Kehr
A. Pombo
S. Rahmann
R.F. Schwarz

November 11, 2021 / Development

GAS1 is required for Notch-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium

M. Marczenke
D. Sunaga
O. Popp
I.W. Althaus
S. Sauer
P. Mertins
A. Christ
B.L. Allen
T.E. Willnow

November 25, 2021 / Nature

Cell-type specialization is encoded by specific chromatin topologies

March 01, 2022 / Brain

Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state

S. Smajić
C.A. Prada-Medina
Z. Landoulsi
J. Ghelfi
S. Delcambre
C. Dietrich
J. Jarazo
J. Henck
S. Balachandran
S. Pachchek
C.M. Morris
P. Antony
B. Timmermann
S. Sauer
S.L. Pereira
J.C. Schwamborn
P. May
A. Grünewald
M. Spielmann

November 05, 2021 / Plant J

Single-nuclei RNA-sequencing of plant tissues using a nanowell-based system

D. Sunaga-Franze
J.M. Muino
C. Braeuning
X. Xu
M. Zong
C. Smaczniak
W. Yan
C. Fischer
R. Vidal
M. Kliem
K. Kaufmann
S. Sauer

May 01, 2021 / Nat Methods

Comparison of the Hi-C, GAM and SPRITE methods using polymer models of chromatin

L. Fiorillo
F. Musella
M. Conte
R. Kempfer
A.M. Chiariello
S. Bianco
A. Kukalev
I. Irastorza-Azcarate
A. Esposito
A. Abraham
A. Prisco
A. Pombo
M. Nicodemi

June 01, 2021 / Proc Natl Acad Sci U S A

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53

J. Heuberger
J. Grinat
F. Kosel
L. Liu
S. Kunz
R.O. Vidal
M. Keil
J. Haybaeck
S. Robine
D. Louvard
C. Regenbrecht
A. Sporbert
S. Sauer
B. von Eyss
M. Sigal
W. Birchmeier

May 01, 2023 / Nat Genet

Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells

R. Chamorro González
T. Conrad
M.C. Stöber
R. Xu
M. Giurgiu
E. Rodriguez-Fos
K. Kasack
L. Brückner
E. van Leen
K. Helmsauer
H. Dorado Garcia
M.E. Stefanova
K.L. Hung
Y. Bei
K. Schmelz
M. Lodrini
S. Mundlos
H.Y. Chang
H.E. Deubzer
S. Sauer
A. Eggert
J.H. Schulte
R.F. Schwarz
K. Haase
R.P. Koche
A.G. Henssen

June 13, 2023 / Immunity

A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation

P. Vallecillo-García
M. Orgeur
G. Comai
S. Poehle-Kronnawitter
C. Fischer
M. Gloger
C.E. Dumas
C. Giesecke-Thiel
S. Sauer
S. Tajbakhsh
U.E. Höpken
S. Stricker

July 01, 2023 / Nat Methods

Multiplex-GAM: genome-wide identification of chromatin contacts yields insights overlooked by Hi-C

R.A. Beagrie
C.J. Thieme
C. Annunziatella
C. Baugher
Y. Zhang
M. Schueler
A. Kukalev
R. Kempfer
A.M. Chiariello
S. Bianco
Y. Li
T. Davis
A. Scialdone
L.R. Welch
M. Nicodemi
A. Pombo