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Simon Haas receives the Young Investigator Award 2022 of the German Stem Cell Network (GSCN). Haas leads the research group Systemic Hematology, Stem Cells & Precision Medicine in the joint research focus "Single Cell Approaches for Personalized Medicine" of BIH, Charité and MDC.

Daria Bunina has been the head of a new lab at the MDC since July 2022. Her team is researching how epigenetic factors affect cell differentiation. When errors in this process occur, cardiovascular diseases and neurodevelopmental disorders can result.

Blood vessels must adapt their growth to the nutrients available in their surroundings so that they can keep organs adequately supplied. A team led by Michael Potente has identified two proteins that are important for this process and published their findings in "Nature Metabolism".

Pediatric oncologist Anton Henssen and a group of researchers from the US and the UK have won funding for a Cancer Grand Challenge. The international team will receive almost €24 million to research the role that ring-shaped strands of DNA play in the development of cancer, and how to fight them.

Stem cells in the bone marrow form the cells of the blood throughout life. In the process, mistakes can occur leading to cancer. Together with a research team from Berlin, Heidelberg and Boston, Simon Haas describes in "Cell Stem Cell" a mechanism that allows the body to protect itself from this risk.

Research teams at the MDC and partner institutions used a total of 52,132 animals in studies conducted in 2021 at the MDC’s locations in Berlin-Buch and Mitte. The MDC has now submitted these figures to the regulatory authority, the Berlin State Office for Health and Social Affairs (LaGeSo).

Research to improve human health is currently not possible without animal testing. At the same time, scientists are searching for alternatives. In the current episode of the Berlin Research 50 (BR50) podcast, Thomas Prinzler discusses progress and limitations with Berlin experts.

Using pioneering methods of proteome analysis, an interdisciplinary team of Berlin researchers was able to decode a previously unknown mechanism which can cause bone marrow cancer to relapse. The teams led by Jan Krönke and Philipp Mertins report their results in “Nature Communications”.

Until now, it was unknown how a new blood vessel obtains the suitable diameter. A team led by MDC researcher Holger Gerhardt has published a paper in the journal "Development" outlining how targeted migration of newly formed cells from the veins toward the arteries is crucial in this process.

Both researchers study communication, but at different levels: Dr. Stefanie Grosswendt and Dr. Alison Barker have been awarded European Research Council (ERC) Starting Grants. The prestigious grants provide about €1.5 million in funding over a period of five years.