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Cancer immunologist Lydia Dyck has started her Marie Curie Postdoctoral Fellowship at the MDC. Her goal is to find new ways for the immune system to recognize and eliminate cancer cells, as tumors often evade the body’s defense mechanisms.

T-knife, a spin-off from the MDC and Charité, has raised 110 million U.S. dollars from international investors. The Berlin-based biotech company is developing novel immunotherapies against cancer that focus on teaching a patient’s T cells to recognize and fight solid tumors.

A young Berlin-based company called T-knife is a rising star in Germany’s biotech sector. Co-founder Dr. Elisa Kieback, along with colleagues, has catapulted the joint spin-off from the MDC and Charité to the top of the German biotech start-up universe.

Researchers from the MDC and Charité have developed a new gene therapy based around a special T-cell receptor that helps the immune system effectively recognize and fight cancer cells. The safety of the novel therapy is now being tested on patients with bone marrow cancer in a phase I clinical trial.

Every year, some 510,000 people in Germany are diagnosed with cancer – and there are over four million people in the country today living with a cancer diagnosis. On the occasion of World Cancer Day on February 4, the Max Delbrück Center for Molecular Medicine (MDC) is giving media representatives an opportunity to hear from experts on the current state of cancer research.

Its official description, a “specialized science library serving the staff of the MDC,” sounds as dry as a dusty bookshelf. What else does the MDC library have to offer? We answer that question in an interview with Wolf Schröder-Barkausen, in another installment of our series “We at the MDC.”

MDC researchers have developed a new approach to CAR T-cell therapy. The team has shown in Nature Communications that the procedure is very effective, especially when it comes to fighting follicular lymphomas and chronic lymphocytic leukemia, the most common type of blood cancer in adults.

The Berlin biotech start-up T-knife, a spin-off from the MDC together with Charité, has secured investments totaling €66 million. Four venture capital funds committed to the financing in early August. T-knife develops new cancer treatments using modified immune system T cells.

Strategies for treating multiple sclerosis have so far focused primarily on T and B cells. A group of MDC researchers has now unveiled a new approach in Nature Immunology – one that seeks to increase treatment effectiveness by selectively targeting another type of immune cell called monocytes.

Thomas Blankenstein receives an ERC Advanced grant for cancer research. The scientist wants to find out if T cells control the development of cancer by a process called immunosurveillance. For this purpose he now proposes a new research model.