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UID:65555f28a563e245578bb217b14fe3e0
DTSTART;TZID=Europe/Berlin:20180731T120000
SEQUENCE:0
TRANSP:OPAQUE
URL:https://www.mdc-berlin.de/news/events/prof-thomas-sudhof-role-synaptic-
 cell-adhesion-molecules-synaptic-connectivity-case
LOCATION:Robert-Rössle-Str. 10 Max Delbrück Communications Center\,13125\
 nBerlin\,Germany
SUMMARY:Prof. Thomas Südhof\, “The role of synaptic cell-adhesion molecu
 les in synaptic connectivity: The case of neuroligins”
CLASS:PUBLIC
DESCRIPTION:Humans can think\, feel and act because synapses translate elec
 trical\nsignals into chemical ones and send them via a gap to the next ner
 ve\ncell. The reception is partly dependent on neuroligins. In a lecture\n
 at the MDC on July 31\, Nobel Prize winner Thomas Südhof (Stanford)\nwill
  explain their role.\n\nAs a graduate student\, Thomas Südhof described t
 he release of\nhormones from neuroendocrine cells of the adrenal glands. D
 uring his\npost-doctoral time\, he investigated the role of the LDL recept
 or in\ncholesterol metabolism\, for which M. S. Brown and J. L. Goldstein 
 were\nawarded the Nobel Prize in Physiology or Medicine in 1985. Later on\
 ,\nhe focused on the study of the molecular machinery mediating\nneurotran
 smitter release and discovered key molecules on synapse\nformation. Südho
 f’s findings have not only provided a better\nunderstanding of the proce
 sses underlying synapse formation and\ncommunication\, but has also advanc
 ed knowledge of mechanisms behind\npoorly understood diseases such as schi
 zophrenia\, autism and\nAlzheimer´s disease. For his breakthroughs\, Süd
 hof was awarded the\n2013 Nobel Prize for Physiology or Medicine\, which h
 e shared with J.\nE. Rothman and R. W. Schekman.\n
X-ALT-DESC;FMTTYPE=text/html:<p>Humans can think\, feel and act because syn
 apses translate electrical signals into chemical ones and send them via a 
 gap to the next nerve cell. The reception is partly dependent on neuroligi
 ns. In a lecture at the MDC on July 31\, Nobel Prize winner Thomas Südhof
  (Stanford) will explain their role.</p>\n\n<p>As a graduate student\, Tho
 mas Südhof described the release of hormones from neuroendocrine cells of
  the adrenal glands. During his post-doctoral time\, he investigated the r
 ole of the LDL receptor in cholesterol metabolism\, for which M. S. Brown 
 and J. L. Goldstein were awarded the Nobel Prize in Physiology or Medicine
  in 1985. Later on\, he focused on the study of the molecular machinery me
 diating neurotransmitter release and discovered key molecules on synapse f
 ormation. Südhof’s findings have not only provided a better understandi
 ng of the processes underlying synapse formation and communication\, but h
 as also advanced knowledge of mechanisms behind poorly understood diseases
  such as schizophrenia\, autism and Alzheimer´s disease. For his breakthr
 oughs\, Südhof was awarded the 2013 Nobel Prize for Physiology or Medicin
 e\, which he shared with J. E. Rothman and R. W. Schekman.</p>
DTSTAMP:20240529T172205Z
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