Tursun Lab

Tursun Lab

Gene Regulation and Cell Fate Decision in C. elegans

Profile

Understanding mechanisms which safeguard cellular identities is key to improving the reprogramming of differentiated cells.

We use Caenorhabditis elegans as a genetic model organism to systematically study the molecular basis of cell fate maintenance and protection. C. elegans provides genetic tractability and visualization of cell conversions in vivo.

We utilized large-scale genetic screens to identify factors safeguarding cell fates and acting as a barrier for direct conversion of cells to a different identity (Transdifferentiation / Direct Reprogramming). Additionally, we are studying the interconnection of Aging and Cellular Reprogramming.

Our findings could help overcome the limitations of Direct Reprogramming in order to generate the cellular material for prospective tissue replacement therapies.

To learn more about the Tursun Research Group please visit our lab website: Tursunlab.org

 

 

 

Publications

Dr. Baris Tursun
Dr. Baris Tursun
Group Leader
Contact
Max-Delbrück-Centrum für Molekulare Medizin (MDC)
Robert-Rössle-Str. 10
13092 Berlin, Germany
 
Building 89, Room 0.19a
 
(030) 9406 1730
 
Secretariat
 
Ines Krock
 
Building 89, Room 0.04a
 
(030) 9406 1753