Tursun Lab

Tursun Lab

Gene Regulation and Cell Fate Decision in C. elegans


Understanding mechanisms which safeguard cellular identities is key to improving the reprogramming of differentiated cells.

We use Caenorhabditis elegans as a genetic model organism to systematically study the molecular basis of cell fate maintenance and protection. C. elegans provides genetic tractability and visualization of cell conversions in vivo.

We utilized large-scale genetic screens to identify factors safeguarding cell fates and acting as a barrier for direct conversion of cells to a different identity (Transdifferentiation / Direct Reprogramming). Additionally, we are studying the interconnection of Aging and Cellular Reprogramming.

Our findings could help overcome the limitations of Direct Reprogramming in order to generate the cellular material for prospective tissue replacement therapies.

To learn more about the Tursun Research Group please visit our lab website: Tursunlab.org






Dr. Baris Tursun
Dr. Baris Tursun
Group Leader
Max-Delbrück-Centrum für Molekulare Medizin (MDC)
Robert-Rössle-Str. 10
13092 Berlin, Germany
Building 89, Room 0.19a
(030) 9406 1730
Ines Krock
Building 89, Room 0.04a
(030) 9406 1753