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Mai 2017 / Cell Stem Cell Human iPSC-derived neural progenitors are an effective drug discovery model for neurological mtDNA disorders C. Lorenz P. Lesimple R. Bukowiecki A. Zink G. Inak B. Mlody M. Singh M. Semtner N. Mah K. Auré M. Leong O. Zabiegalov E.M. Lyras V. Pfiffer B. Fauler J. Eichhorst B. Wiesner N. Huebner J. Priller T. Mielke D. Meierhofer Z. Izsvák J.C. Meier F. Bouillaud J. Adjaye M. Schuelke E.E. Wanker A. Lombès A. Prigione 01. Januar 2017 / Lett Drug Des Discov In vitro and in vivo investigations into the carbene gold chloride and thioglucoside anticancer drug candidates NHC-AuCl and NHC-AuSR W. Walther O. Dada C. O’Beirne I. Ott G. Sanchez-Sanz C. Schmidt C. Werner X. Zhu M. Tacke 01. Mai 2017 / Pharmacol Ther Pancreatic cancer models for translational research D. Behrens W. Walther I. Fichtner 13. Februar 2017 / BMC Cancer Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy J. Pahle L. Menzel N. Niesler D. Kobelt J. Aumann M. Rivera W. Walther 16. März 2017 / Mol Cell Identification of an RNA polymerase III regulator linked to disease-associated protein aggregation O. Sin T. de Jong A. Mata-Cabana M. Kudron M.A. Zaini F.A. Aprile R.I. Seinstra E. Stroo R.W. Prins C.N. Martineau H.H. Wang Wytse Hogewerf A. Steinhof E.E. Wanker M. Vendruscolo C.F. Calkhoven V. Reinke V. Guryev E.A.A. Nollen 01. April 2017 / Cancer Treat Rev Choosing wisely - Preclinical test models in the era of precision medicine K. Klinghammer W. Walther J. Hoffmann 26. April 2017 / J Am Chem Soc Inhibition of huntingtin exon-1 aggregation by the molecular tweezer CLR01 T. Vöpel K. Bravo-Rodriguez S. Mittal S. Vachharajani D. Gnutt A. Sharma A. Steinhof O. Fatoba G. Ellrichmann M. Nshanian C. Heid J.A. Loo F.-G. Klärner T. Schrader G. Bitan E.E. Wanker S. Ebbinghaus E. Sanchez-Garcia 01. August 2017 / Ann Oncol Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies U.P. Rohr P. Herrmann K. Ilm H. Zhang S. Lohmann A. Reiser A. Muranyi J. Smith S. Burock M. Osterland K. Leith S. Singh P. Brunhoeber R. Bowermaster J. Tie M. Christie H.L. Wong P. Waring K. Shanmugam P. Gibbs U. Stein 13. März 2017 / Sci Rep The redox environment triggers conformational changes and aggregation of hIAPP in type II diabetes D.C. Rodriguez Camargo K. Tripsianes K. Buday A. Franko C. Göbl C. Hartlmüller R. Sarkar M. Aichler G. Mettenleiter M. Schulz A. Böddrich C. Erck H. Martens A.K. Walch T. Madl E.E. Wanker M. Conrad M.H. de Angelis B. Reif 01. Juni 2017 / Magn Reson Med Myocardial effective transverse relaxation time T(2)* correlates with left ventricular wall thickness: a 7.0 T MRI study T. Huelnhagen F. Hezel T. Serradas Duarte A. Pohlmann C. Oezerdem B. Flemming E. Seeliger M. Prothmann J. 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04. Mai 2017 / Cell Stem Cell Human iPSC-derived neural progenitors are an effective drug discovery model for neurological mtDNA disorders C. Lorenz P. Lesimple R. Bukowiecki A. Zink G. Inak B. Mlody M. Singh M. Semtner N. Mah K. Auré M. Leong O. Zabiegalov E.M. Lyras V. Pfiffer B. Fauler J. Eichhorst B. Wiesner N. Huebner J. Priller T. Mielke D. Meierhofer Z. Izsvák J.C. Meier F. Bouillaud J. Adjaye M. Schuelke E.E. Wanker A. Lombès A. Prigione
01. Januar 2017 / Lett Drug Des Discov In vitro and in vivo investigations into the carbene gold chloride and thioglucoside anticancer drug candidates NHC-AuCl and NHC-AuSR W. Walther O. Dada C. O’Beirne I. Ott G. Sanchez-Sanz C. Schmidt C. Werner X. Zhu M. Tacke
01. Mai 2017 / Pharmacol Ther Pancreatic cancer models for translational research D. Behrens W. Walther I. Fichtner
13. Februar 2017 / BMC Cancer Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy J. Pahle L. Menzel N. Niesler D. Kobelt J. Aumann M. Rivera W. Walther
16. März 2017 / Mol Cell Identification of an RNA polymerase III regulator linked to disease-associated protein aggregation O. Sin T. de Jong A. Mata-Cabana M. Kudron M.A. Zaini F.A. Aprile R.I. Seinstra E. Stroo R.W. Prins C.N. Martineau H.H. Wang Wytse Hogewerf A. Steinhof E.E. Wanker M. Vendruscolo C.F. Calkhoven V. Reinke V. Guryev E.A.A. Nollen
01. April 2017 / Cancer Treat Rev Choosing wisely - Preclinical test models in the era of precision medicine K. Klinghammer W. Walther J. Hoffmann
26. April 2017 / J Am Chem Soc Inhibition of huntingtin exon-1 aggregation by the molecular tweezer CLR01 T. Vöpel K. Bravo-Rodriguez S. Mittal S. Vachharajani D. Gnutt A. Sharma A. Steinhof O. Fatoba G. Ellrichmann M. Nshanian C. Heid J.A. Loo F.-G. Klärner T. Schrader G. Bitan E.E. Wanker S. Ebbinghaus E. Sanchez-Garcia
01. August 2017 / Ann Oncol Prognostic value of MACC1 and proficient mismatch repair status for recurrence risk prediction in stage II colon cancer patients: the BIOGRID studies U.P. Rohr P. Herrmann K. Ilm H. Zhang S. Lohmann A. Reiser A. Muranyi J. Smith S. Burock M. Osterland K. Leith S. Singh P. Brunhoeber R. Bowermaster J. Tie M. Christie H.L. Wong P. Waring K. Shanmugam P. Gibbs U. Stein
13. März 2017 / Sci Rep The redox environment triggers conformational changes and aggregation of hIAPP in type II diabetes D.C. Rodriguez Camargo K. Tripsianes K. Buday A. Franko C. Göbl C. Hartlmüller R. Sarkar M. Aichler G. Mettenleiter M. Schulz A. Böddrich C. Erck H. Martens A.K. Walch T. Madl E.E. Wanker M. Conrad M.H. de Angelis B. Reif
01. Juni 2017 / Magn Reson Med Myocardial effective transverse relaxation time T(2)* correlates with left ventricular wall thickness: a 7.0 T MRI study T. Huelnhagen F. Hezel T. Serradas Duarte A. Pohlmann C. Oezerdem B. Flemming E. Seeliger M. Prothmann J. Schulz-Menger T. Niendorf