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Wissenschaftliche Publikationen

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/ J Genet Genomics

Phosphatidylinositol 4 kinase-β mutations cause non-syndromic sensorineural deafness and inner ear malformation

  • X. Su
  • Y. Feng
  • S.A. Rahman
  • S. Wu
  • G. Li
  • F. Rüschendorf
  • L. Zhao
  • H. Cui
  • J. Liang
  • L. Fang
  • H. Hu
  • S. Froehler
  • Y. Yu
  • G. Patone
  • O. Hummel
  • Q. Chen
  • K. Raile
  • F.C. Luft
  • S. Bähring
  • K. Hussain
  • W. Chen
  • J. Zhang
  • M. Gong
/ Nat Biomed Eng

Enhanced precision and efficiency

  • S. Bashir
  • R. Kühn
/ J Neurosci Res

Forebrain-specific knockout of B-raf kinase leads to deficits in hippocampal long-term potentiation, learning, and memory

  • A.P. Chen
  • M. Ohno
  • K.P. Giese
  • R. Kühn
  • R.L. Chen
  • A.J. Silva
/ PLoS ONE

An RNAi-based approach to down-regulate a gene family in vivo

  • J. Kim
  • A. Badaloni
  • T. Willert
  • U. Zimber-Strobl
  • R. Kühn
  • W. Wurst
  • M. Kieslinger
/ Nat Protoc

Generation of targeted mouse mutants by embryo microinjection of TALEN mRNA

  • B. Wefers
  • S.K. Panda
  • O. Ortiz
  • C. Brandl
  • S. Hensler
  • J. Hansen
  • W. Wurst
  • R. Kühn
/ Genetics

Highly efficient targeted mutagenesis in mice using TALENs

  • S.K. Panda
  • B. Wefers
  • O. Ortiz
  • T. Floss
  • B. Schmid
  • C. Haass
  • W. Wurst
  • R. Kühn
/ Genesis

Reversible and tissue-specific activation of MAP kinase signaling by tamoxifen in Braf(V637)ER(T2) mice

  • O. Ortiz
  • W. Wurst
  • R. Kühn
/ Proc Natl Acad Sci U S A

Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides

  • B. Wefers
  • M. Meyer
  • O. Ortiz
  • M. Hrabé de Angelis
  • J. Hansen
  • W. Wurst
  • R. Kühn
/ PLoS ONE

Efficient generation of rat induced pluripotent stem cells using a non-viral inducible vector

  • C. Merkl
  • A. Saalfrank
  • N. Riesen
  • R. Kühn
  • A. Pertek
  • S. Eser
  • M.S. Hardt
  • A. Kind
  • D. Saur
  • W. Wurst
  • A. Iglesias
  • A. Schnieke
/ PLoS ONE

In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis

  • I. Klymiuk
  • L. Kenner
  • T. Adler
  • D.H. Busch
  • A. Boersma
  • M. Irmler
  • B. Fridrich
  • V. Gailus-Durner
  • H. Fuchs
  • N. Leitner
  • M. Mueller
  • R. Kuehn
  • M. Schlederer
  • I. Treise
  • M.H. de Angelis
  • J. Beckers