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Juni 2023 / Nat Commun Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy M. Grosch L. Schraft A. Chan L. Küchenhoff K. Rapti A.M. Ferreira J. Kornienko S. Li M.H. Radke C. Krämer S. Clauder-Münster E. Perlas J. Backs M. Gotthardt C. Dieterich M.M.G. van den Hoogenhof D. Grimm L.M. Steinmetz 01. September 2014 / J Cell Sci Deletion of the titin N2B region accelerates myofibrillar force development but does not alter relaxation kinetics F. Elhamine M. Radke G. Pfitzer H. Granzier M. Gotthardt R. Stehle 01. Dezember 2016 / J Mol Med Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy F. Hinze C. Dieterich M.H. Radke H. Granzier M. Gotthardt 23. Januar 2015 / J Biol Chem The Src Homology and Collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development M. Mlih L. Host S. Martin N. Niederhoffer L. Monassier J. Terrand N. Messaddeq M. Radke M. Gotthardt V. Bruban F. Kober M. Bernard E. Canet-Soulas F. Abt-Jijon P. Boucher R.L. Matz 14. Januar 2015 / Sci Transl Med Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease A.M. Roberts J.S. Ware D.S. Herman S. Schafer J. Baksi A.G. Bick R.J. Buchan R. Walsh S. John S. Wilkinson F. Mazzarotto L.E. Felkin S. Gong J.A.L. MacArthur F. Cunningham J. Flannick S.B. Gabriel D.M. Altshuler P.S. Macdonald M. Heinig A.M. Keogh C.S. Hayward N.R. Banner D.J. Pennell D.P. O'Regan T.R. San A. de Marvao T.J.W. Dawes A. Gulati E.J. Birks M.H. Yacoub M. Radke M. Gotthardt J.G. Wilson C.J. O'Donnell S.K. Prasad P.J.R. Barton D. Fatkin N. Hubner J.G. Seidman C.E. Seidman S.A. Cook 21. April 2017 / Science Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat T.J. Park J. Reznick B.L. Peterson G. Blass D. Omerbašić N.C. Bennett P.H.J.L. Kuich C. Zasada B.M. Browe W. Hamann D.T. Applegate M.H. Radke T. Kosten H. Lutermann V. Gavaghan O. Eigenbrod V. Bégay V. G. Amoroso V. Govind R.D. Minshall E.S.J. Smith J. Larson M. Gotthardt S. Kempa G.R. Lewin 27. Februar 2007 / Proc Natl Acad Sci U S A Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy M.H. Radke J. Peng Y. Wu M. McNabb O.L. Nelson H. Granzier M. Gotthardt 01. August 2007 / Am J Physiol Regul Integr Comp Physiol Functional genomics of chicken, mouse, and human titin supports splice diversity as an important mechanism for regulating biomechanics of striated muscle H. Granzier M. Radke J. Royal Y. Wu T.C. Irving M. Gotthardt S. Labeit 01. September 2010 / J Mol Cell Cardiol Calcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region deficient mice E.J. Lee J. Peng M. Radke M. Gotthardt H.L. Granzier 11. September 2009 / Circ Res Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction H.L. Granzier M.H. Radke J. Peng D. Westermann O.L. Nelson K. Rost N.M. King Q. Yu C. Tschoepe M. McNabb D.F. Larson S. Labeit M. Gotthardt Seitennummerierung Aktuelle Seite 1 Seite 2 Seite 3 Nächste Seite Next › Letzte Seite Last »
22. Juni 2023 / Nat Commun Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy M. Grosch L. Schraft A. Chan L. Küchenhoff K. Rapti A.M. Ferreira J. Kornienko S. Li M.H. Radke C. Krämer S. Clauder-Münster E. Perlas J. Backs M. Gotthardt C. Dieterich M.M.G. van den Hoogenhof D. Grimm L.M. Steinmetz
01. September 2014 / J Cell Sci Deletion of the titin N2B region accelerates myofibrillar force development but does not alter relaxation kinetics F. Elhamine M. Radke G. Pfitzer H. Granzier M. Gotthardt R. Stehle
01. Dezember 2016 / J Mol Med Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy F. Hinze C. Dieterich M.H. Radke H. Granzier M. Gotthardt
23. Januar 2015 / J Biol Chem The Src Homology and Collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development M. Mlih L. Host S. Martin N. Niederhoffer L. Monassier J. Terrand N. Messaddeq M. Radke M. Gotthardt V. Bruban F. Kober M. Bernard E. Canet-Soulas F. Abt-Jijon P. Boucher R.L. Matz
14. Januar 2015 / Sci Transl Med Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease A.M. Roberts J.S. Ware D.S. Herman S. Schafer J. Baksi A.G. Bick R.J. Buchan R. Walsh S. John S. Wilkinson F. Mazzarotto L.E. Felkin S. Gong J.A.L. MacArthur F. Cunningham J. Flannick S.B. Gabriel D.M. Altshuler P.S. Macdonald M. Heinig A.M. Keogh C.S. Hayward N.R. Banner D.J. Pennell D.P. O'Regan T.R. San A. de Marvao T.J.W. Dawes A. Gulati E.J. Birks M.H. Yacoub M. Radke M. Gotthardt J.G. Wilson C.J. O'Donnell S.K. Prasad P.J.R. Barton D. Fatkin N. Hubner J.G. Seidman C.E. Seidman S.A. Cook
21. April 2017 / Science Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat T.J. Park J. Reznick B.L. Peterson G. Blass D. Omerbašić N.C. Bennett P.H.J.L. Kuich C. Zasada B.M. Browe W. Hamann D.T. Applegate M.H. Radke T. Kosten H. Lutermann V. Gavaghan O. Eigenbrod V. Bégay V. G. Amoroso V. Govind R.D. Minshall E.S.J. Smith J. Larson M. Gotthardt S. Kempa G.R. Lewin
27. Februar 2007 / Proc Natl Acad Sci U S A Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy M.H. Radke J. Peng Y. Wu M. McNabb O.L. Nelson H. Granzier M. Gotthardt
01. August 2007 / Am J Physiol Regul Integr Comp Physiol Functional genomics of chicken, mouse, and human titin supports splice diversity as an important mechanism for regulating biomechanics of striated muscle H. Granzier M. Radke J. Royal Y. Wu T.C. Irving M. Gotthardt S. Labeit
01. September 2010 / J Mol Cell Cardiol Calcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region deficient mice E.J. Lee J. Peng M. Radke M. Gotthardt H.L. Granzier
11. September 2009 / Circ Res Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction H.L. Granzier M.H. Radke J. Peng D. Westermann O.L. Nelson K. Rost N.M. King Q. Yu C. Tschoepe M. McNabb D.F. Larson S. Labeit M. Gotthardt