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Februar 2018 / Cancer Res Adaptive and reversible resistance to Kras inhibition in pancreatic cancer cells P.Y. Chen M.D. Muzumdar K.J. Dorans R.A. Robbins A. Bhutkar A.M. Del Rosario P. Mertins J. Qiao C. Schaefer F.B. Gertler S.A. Carr T. Jacks 01. März 2018 / Nat Genet CLCN2 chloride channel mutations in familial hyperaldosteronism type II U.I. Scholl G. Stölting J. Schewe A. Thiel H. Tan C. Nelson-Williams A.A. Vichot S.C. Jin E. Loring V. Untiet T. Yoo J. Choi S. Xu A. Wu M. Kirchner P. Mertins L.C. Rump A.M. Onder C. Gamble D. McKenney R.W. Lash D.P. Jones G. Chune P. Gagliardi M. Choi R. Gordon M. Stowasser C. Fahlke R.P. Lifton 22. Februar 2018 / Cell Pervasive, coordinated protein-level changes driven by transcript isoform switching during meiosis Z. Cheng G.M. Otto E.N. Powers A. Keskin P. Mertins S.A. Carr M. Jovanovic G.A. Brar 01. Mai 2018 / Cancer Res Mass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple-negative breast cancers F. Mundt S. Rajput S. Li K.V. Ruggles A.D. Mooradian P. Mertins M.A. Gillette K. Krug Z. Guo J. Hoog P. Erdmann-Gilmore T. Primeau S. Huang D.P. Edwards X. Wang X. Wang E. Kawaler D.R. Mani K.R. Clauser F. Gao J. Luo S.R. Davies G.L. Johnson K.L. Huang C.J. Yoon L. Ding D. Fenyö M.J. Ellis R.R. Townsend J.M. Held S.A. Carr C.X. Ma 01. Juli 2018 / Nat Med Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition G.S. Wong J. Zhou J.B. Liu Z. Wu X. Xu T. Li D. Xu S.E. Schumacher J. Puschhof J. McFarland C. Zou A. Dulak L. Henderson P. Xu E. O'Day R. Rendak W.L. Liao F. Cecchi T. Hembrough S. Schwartz C. Szeto A.K. Rustgi K.K. Wong J.A. Diehl K. Jensen F. Graziano A. Ruzzo S. Fereshetian P. Mertins S.A. Carr R. Beroukhim K. Nakamura E. Oki M. Watanabe H. Baba Y. Imamura D. Catenacci A.J. Bass 13. September 2018 / Blood PPM1D truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells J.D. Kahn P.G. Miller A.J. Silver R.S. Sellar S. Bhatt C. Gibson M. McConkey D. Adams B. Mar P. Mertins S. Fereshetian K. Krug H. Zhu A. Letai S.A. Carr J. Doench S. Jaiswal B.L. Ebert 01. Juli 2018 / Nat Protoc Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography-mass spectrometry P. Mertins L.C. Tang K. Krug D.J. Clark M.A. Gritsenko L. Chen K.R. Clauser T.R. Clauss P. Shah M.A. Gillette V.A. Petyuk S.N. Thomas D.R. Mani F. Mundt R.J. Moore Y. Hu R. Zhao M. Schnaubelt H. Keshishian M.E. Monroe Z. Zhang N.D. Udeshi D. Mani S.R. Davies R.R. Townsend D.W. Chan R.D. Smith H. Zhang T. Liu S.A. Carr 01. November 2018 / Mol Biol Cell On the relation between filament density, force generation and protrusion rate in mesenchymal cell motility S. Dolati F. Kage J. Mueller M. Müsken M. Kirchner G. Dittmar M. Sixt K. Rottner M. Falcke 04. September 2018 / Cell Rep Transcriptional and translational differences of microglia from male and female brains D. Guneykaya A. Ivanov D. Perez Hernandez V. Haage B. Wojtas N. Meyer M. Maricos P. Jordan A. Buonfiglioli B. Gielniewski N. Ochocka C. Cömert C. Friedrich L. Suarez Artiles B. Kaminska P. Mertins D. Beule H. Kettenmann S.A. Wolf 10. September 2018 / Cancer Cell Proteomics, post-translational modifications, and integrative analyses reveal molecular heterogeneity within medulloblastoma subgroups T.C. Archer T. Ehrenberger F. Mundt M.P. Gold K. Krug C.K. Mah E.L. Mahoney C.J. Daniel A. LeNail D. Ramamoorthy P. Mertins D.R. Mani H. Zhang M.A. Gillette K. Clauser M. Noble L.C. Tang J. Pierre-François J. Silterra J. Jensen P. Tamayo A. Korshunov S.M. Pfister M. Kool P.A. Northcott R.C. Sears J.O. Lipton S.A. Carr J.P. Mesirov S.L. Pomeroy E. 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15. Februar 2018 / Cancer Res Adaptive and reversible resistance to Kras inhibition in pancreatic cancer cells P.Y. Chen M.D. Muzumdar K.J. Dorans R.A. Robbins A. Bhutkar A.M. Del Rosario P. Mertins J. Qiao C. Schaefer F.B. Gertler S.A. Carr T. Jacks
01. März 2018 / Nat Genet CLCN2 chloride channel mutations in familial hyperaldosteronism type II U.I. Scholl G. Stölting J. Schewe A. Thiel H. Tan C. Nelson-Williams A.A. Vichot S.C. Jin E. Loring V. Untiet T. Yoo J. Choi S. Xu A. Wu M. Kirchner P. Mertins L.C. Rump A.M. Onder C. Gamble D. McKenney R.W. Lash D.P. Jones G. Chune P. Gagliardi M. Choi R. Gordon M. Stowasser C. Fahlke R.P. Lifton
22. Februar 2018 / Cell Pervasive, coordinated protein-level changes driven by transcript isoform switching during meiosis Z. Cheng G.M. Otto E.N. Powers A. Keskin P. Mertins S.A. Carr M. Jovanovic G.A. Brar
01. Mai 2018 / Cancer Res Mass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple-negative breast cancers F. Mundt S. Rajput S. Li K.V. Ruggles A.D. Mooradian P. Mertins M.A. Gillette K. Krug Z. Guo J. Hoog P. Erdmann-Gilmore T. Primeau S. Huang D.P. Edwards X. Wang X. Wang E. Kawaler D.R. Mani K.R. Clauser F. Gao J. Luo S.R. Davies G.L. Johnson K.L. Huang C.J. Yoon L. Ding D. Fenyö M.J. Ellis R.R. Townsend J.M. Held S.A. Carr C.X. Ma
01. Juli 2018 / Nat Med Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition G.S. Wong J. Zhou J.B. Liu Z. Wu X. Xu T. Li D. Xu S.E. Schumacher J. Puschhof J. McFarland C. Zou A. Dulak L. Henderson P. Xu E. O'Day R. Rendak W.L. Liao F. Cecchi T. Hembrough S. Schwartz C. Szeto A.K. Rustgi K.K. Wong J.A. Diehl K. Jensen F. Graziano A. Ruzzo S. Fereshetian P. Mertins S.A. Carr R. Beroukhim K. Nakamura E. Oki M. Watanabe H. Baba Y. Imamura D. Catenacci A.J. Bass
13. September 2018 / Blood PPM1D truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells J.D. Kahn P.G. Miller A.J. Silver R.S. Sellar S. Bhatt C. Gibson M. McConkey D. Adams B. Mar P. Mertins S. Fereshetian K. Krug H. Zhu A. Letai S.A. Carr J. Doench S. Jaiswal B.L. Ebert
01. Juli 2018 / Nat Protoc Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography-mass spectrometry P. Mertins L.C. Tang K. Krug D.J. Clark M.A. Gritsenko L. Chen K.R. Clauser T.R. Clauss P. Shah M.A. Gillette V.A. Petyuk S.N. Thomas D.R. Mani F. Mundt R.J. Moore Y. Hu R. Zhao M. Schnaubelt H. Keshishian M.E. Monroe Z. Zhang N.D. Udeshi D. Mani S.R. Davies R.R. Townsend D.W. Chan R.D. Smith H. Zhang T. Liu S.A. Carr
01. November 2018 / Mol Biol Cell On the relation between filament density, force generation and protrusion rate in mesenchymal cell motility S. Dolati F. Kage J. Mueller M. Müsken M. Kirchner G. Dittmar M. Sixt K. Rottner M. Falcke
04. September 2018 / Cell Rep Transcriptional and translational differences of microglia from male and female brains D. Guneykaya A. Ivanov D. Perez Hernandez V. Haage B. Wojtas N. Meyer M. Maricos P. Jordan A. Buonfiglioli B. Gielniewski N. Ochocka C. Cömert C. Friedrich L. Suarez Artiles B. Kaminska P. Mertins D. Beule H. Kettenmann S.A. Wolf
10. September 2018 / Cancer Cell Proteomics, post-translational modifications, and integrative analyses reveal molecular heterogeneity within medulloblastoma subgroups T.C. Archer T. Ehrenberger F. Mundt M.P. Gold K. Krug C.K. Mah E.L. Mahoney C.J. Daniel A. LeNail D. Ramamoorthy P. Mertins D.R. Mani H. Zhang M.A. Gillette K. Clauser M. Noble L.C. Tang J. Pierre-François J. Silterra J. Jensen P. Tamayo A. Korshunov S.M. Pfister M. Kool P.A. Northcott R.C. Sears J.O. Lipton S.A. Carr J.P. Mesirov S.L. Pomeroy E. Fraenkel