A Clamp for Emerging Flu Viruses - Researchers in Freiburg and Berlin Unravel Secret of Innate Immune Response
When the human body becomes infected with new influenza viruses, the immune system rapidly activates an inborn protective mechanism to inhibit the intruding pathogen. A protein known as Mx plays an important role in this process, keeping the spread of viruses in check. Exactly how Mx accomplishes this task was previously unknown. Now virologists from the Institute of Medical Microbiology at the Freiburg University Medical Center and biochemists from the Max Delbrück Center for Molecular Medicine (MDC) in Berlin-Buch, Germany, have unraveled the structure of the Mx protein and are able to explain how it develops its anti-viral effect (Nature, doi: 10.1038/nature08972)*.