Max Delbrück Center MDC - Max-Delbrück-Centrum für molekulare Medizin in der Helmholtz-Gemeinschaft

Our Research

Research at the Max Delbrück Center aims to elucidate the molecular mechanisms of health and disease, and translate those findings into medical practice.

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Research Highlights

Our research teams publish around 450 specialist articles every year. Our research highlights can be found here, presented in a comprehensible format.

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Selection of research highlights
induced pluripotent stem cells in a pluripotency test

Research News & Events

Summit 24- Maike Sander

Perspectives for the medicine of the future

What opportunities lie ahead for the future of medical research and healthcare? Scientists from the Helmholtz Association share their ideas with decision-makers from science, politics, patient organizations, biotech, and the pharmaceutical industry at the first Helmholtz Health Summit in Berlin.
Porträt Maike Sander MDC
Science

Medicine Needs More Innovation

We at the Helmholtz Association have everything we need to leverage the potential of biomedical engineering in Germany. We simply need to assemble all the puzzle pieces thoughtfully and unite people who have never collaborated before, says our Scientific Director Maike Sander.
Ashley Sanders
Science

The pioneer of single-cell sequencing

Ashley Sanders, Group Leader of the Genome Instability and Somatic Mosaicism Lab, developed a technique to sequence strands of DNA in single cells. Today it is the most accurate method to detect DNA rearrangements. She hopes the technique will help reveal clues on how diseases develop.
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Science

New images through high magnetic field strengths

In mid-September, researchers from all over the world gathered in Berlin to explore the current and future possibilities of magnetic resonance imaging. The annual symposium was hosted by the team of physicist Professor Thoralf Niendorf from the Max Delbrück Center.
Enno Klußmann
Science

Hypertension with less harm

Enno Klußmann of the Max Delbrück Center aims to help reducing the harmful consequences of high blood pressure by imitating a rare mutation. His plan to activate a specific enzyme called PDE3A to protect the heart and kidneys is now being funded with €400,000 by the Else Kröner-Fresenius Foundation.
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Science

Modelling the human kidney with organoids

Dr. Melissa Little, a world leader in stem cell research, successfully developed the first kidney organoid. In advance of her lecture at the Max Delbrück Center, she shares insights about the road to that eureka moment, the journey since and the state of stem cell and organoid research today.
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Human and other primate hearts differ genetically

A team in the Hübner and Diecke Labs at the Max Delbrück Center have shown how human and non-human primate hearts differ genetically. The study, published in “Nature Cardiovascular Research,” reveals evolutionary adaptations in human hearts and provides new insights into cardiac disease.
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Gut microbiome influences location of immune cells

Researchers at the Experimental and Clinical Research Center of Max Delbrück Center and Charité – Universitätsmedizin Berlin have found that microbial communities in the mouse GI tract are unevenly distributed, which influences immune cell populations. The work was published in “Gut Microbes.”
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Institute & Campus

Tim Flink heads the Strategy Unit

A political scientist and expert in research policy, Tim Flink plans to enhance collaboration, align research with industry needs, and strengthen our societal and political relevance.

All News & Events

Publications

From regulation of cell fate decisions towards patient-specific treatments, insights from mechanistic models of signalling pathways

Curr Opin Syst Biol

Characterization of two iPSC lines from patients with maternally inherited leigh (MILS) and neuropathy, ataxia, and retinitis pigmentosa (NARP) syndrome carrying the MT-ATP6 m.8993 T>G mutation at different degrees of heteroplasmy

Stem Cell Res

A point-of-research decision in synovial tissue engineering: Mesenchymal stromal cells, tissue derived fibroblast or CTGF-mediated mesenchymal-to-fibroblast transition

Eur J Cell Biol

Eculizumab use in neuromyelitis optica spectrum disorders: routine clinical care data from a european cohort

Neurology

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