circRNAs (zirkuläre RNAs) in neuralen Zellen

Understanding the molecular basis of health and disease

Technology Platform Flow Cytometry

Innovating medical therapies and clinical diagnostics

Technology Platform Bioinformatics

Developing game changing methods and technologies

MDC_Juli_2017_5615.jpg

Supporting scientific education and career development

Research at the MDC

Research at the MDC aims to elucidate the molecular mechanisms of health and disease, and translate those findings into medical practice.

Research

Research Teams

Our independent research teams pursue their research in Cardiovascular and Metabolic Disease, Cancer Research, Diseases of the Nervous System, and Medical Systems Biology.

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Discover our research groups
Jonathan Alles und Angela Merkel

New research building in Berlin Mitte

With a clear commitment to research and health science, Chancellor Angela Merkel opened the new MDC research building for the Berlin Institute for Molecular Systems Biology.

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Explore our new building
induced pluripotent stem cells in a pluripotency test

Research News & Events

human cardiomyocytes that were derived from induced pluripotent stem cells

Straight to the heart

An international team of researchers are seeking to explore the heart at a depth that was previously impossible. They have now received a grant of nearly four million US dollars from the Chan Zuckerberg Initiative – as one of the 38 Seed Networks working on the Human Cell Atlas. MDC researcher Norbert Hübner is co-coordinator of the project.
The picture shows how the cells of a brain tumour (glioma cells) and microglia communicate with each other.
Science

Brain Tumor Meeting: No two gliomas are the same

In late May, some 350 scientists met at the MDC for the 10th Brain Tumor Meeting. The president of this conference series, Professor Helmut Kettenmann, recounts the event’s highlights and explains why brain tumor research needs to differentiate between men and women.
Long Night of the Sciences 2019
Institute & Campus

That was the Long Night of the Sciences 2019 in Buch and Mitte

It was tropical hot, it was exciting, and it was playful, funny and inspiring. For the Long Night of Science 2019, the MDC attracted its visitors for the first time not only to the Campus Buch, but also to the new research building in Mitte.
molecule model
Science

How cells devour themselves

Cells sometimes love themselves to pieces – and develop a big appetite for their own components. A group of researchers led by Professor Oliver Daumke of the MDC has now discovered how certain molecules trigger this self-cleaning process.
Lange Nacht der Wissenschaften 2019

Creative minds, CRISPR, and cats

Anyone wishing to uncover the mysteries of life must explore the realm of molecules and genes. At the Long Night of the Sciences, visitors to the MDC will voyage through this fascinating cosmos in the company of experts.
Highveld Mole Rat

Pain free, thanks to evolution

African mole-rats are insensitive to many different kinds of pain. As an international research team led by the MDC’s Gary Lewin reports in Science, this characteristic has even allowed mole-rats to populate new habitats. Thanks to a genetic change, the highveld mole-rat is able to live alongside venomous ants with painful stings that other mole-rats avoid.
Norbert Hübner PM - Bildung von Mikroproteinen

Unknown mini-proteins in the heart

A team led by Professor Norbert Hübner’s MDC research group has observed the human heart cells’ “protein factories” in action, examining the entire tissue for the very first time. In an article published in Cell, the group reveals their surprising discoveries and the possibilities they contain for the future treatment of heart disease.
Gary Lewin receives Ernst Jung Prize for Medicine

Deciphering molecular mechanisms and using them for treatment

Ernst Jung Prize for Medicine 2019 goes to Professor Gary R. Lewin from the MDC
Thomas Sommer
Institute & Campus

Between Buch and Haifa

The cellular biologist Thomas Sommer, who is the interim Scientific Director of the MDC, is celebrating his 60th birthday on May 23. We congratulate him on this milestone.

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Publications

4D flow imaging with 2D-selective excitation

Magn Reson Med

Caloric restriction induces H(2)O(2) formation as a trigger of AMPK-eNOS-NO pathway in obese rats: Role for CAMKII

Free Radic Biol Med

Porous medium 3D flow simulation of contrast media washout in cardiac MRI reflects myocardial injury

Magn Reson Med

Neural mechanisms of perceptual decision-making and their link to neuropsychiatric symptoms in multiple sclerosis

Mult Scler Relat Disord

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