circRNAs (zirkuläre RNAs) in neuralen Zellen

Understanding the molecular basis of health and disease

Technology Platform Flow Cytometry

Innovating medical therapies and clinical diagnostics

Technology Platform Bioinformatics

Developing game changing methods and technologies

MDC_Juli_2017_5615.jpg

Supporting scientific education and career development

Research at the MDC

Research at the MDC aims to elucidate the molecular mechanisms of health and disease, and translate those findings into medical practice.

Research

Research Teams

Our independent research teams pursue their research in Cardiovascular and Metabolic Disease, Cancer Research, Diseases of the Nervous System, and Medical Systems Biology.

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Discover our research groups
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Scientific Infrastructure

Our scientific infrastructure provides MDC groups with central access to state-of-the-art technologies which would otherwise demand extensive training and financial investment.

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Explore our scientific infrastructure
induced pluripotent stem cells in a pluripotency test

Research News & Events

Banner mit Nierenkanälchen: Lange Nacht der Wissenschaften 2018 auf dem Campus Buch
Science

From 3D body scanners to the first weighing scales

Science under the stars: This year’s Long Night of the Sciences brought more than 6,000 interested members of the public to the Berlin-Buch campus – despite the intense summer heat.
Zebrafish Heart Looping
14

Polarised cells give the heart its fully developed form

MDC researchers have described how the heart forms itself into a its characteristic S-shape and how the ventricles and atria finally develop. Their findings will help to better understand congenital heart diseases.
Planarian
12

A complete cell atlas and lineage tree of the immortal flatworm

From one stem cell to many differentiated body cells: Scientists from the MDC in Berlin, along with collaborating researchers in Munich, have published a comprehensive lineage tree of a whole adult animal in the journal Science.
Ein neuronales Netzwerk aus zwei Nervenzelle in der Petrischale
10

Keeping the excitement under control

James Poulet's lab listens to the activity of networks of single sensory neurons in the brain and discovered how a single signal from one cell manages to attract attention.
LINNAEUS makes it possible to trace the origin of each cell of a zebrafish
7

Developmental scars

The MDC researcher Jan Philipp Junker and his team have used CRISPR-Cas9 genome editing to pioneer a technique capable of determining both the type and origin of all the cells in an organism. They describe their method in Nature Biotechnology.
FISH
6

LifeTime – a visionary proposal for an EU Flagship

Reliably predicting the onset and trajectory of a disease might seem like a distant dream. But a European consortium is aiming to achieve exactly this using a set of emerging technologies with the analysis of single cells at their core.
Blood
5

How cells protect themselves against mechanical stress

A research team led by Gary Lewin has now discovered that Piezo channels are highly sensitive to changes in membrane voltage.

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Publications

RXR heterodimers orchestrate transcriptional control of neurogenesis and cell fate specification

Mol Cell Endocrinol

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages

Mol Cell Endocrinol

Millimeter spatial resolution in vivo sodium MRI of the human eye at 7 T using a dedicated radiofrequency transceiver array

Magn Reson Med

Auto-antibodies against the angiotensin II type I receptor in women with uteroplacental acute atherosis and preeclampsia at delivery and several years postpartum

J Reprod Immunol

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