MDC Berlin

Dr Sebastian Diecke, who leads the stem cells technology platform at the MDC and BIH, doesn't just do science – he also combines it with art. A project by two Australian artists in which he was involved won an Award of Excellence at this year's Japan Media Arts Festival.

Small changes of sodium in the blood reduce the amount of energy produced in the mitochondria – the power plants of our cells. This has consequences for immune cells. An international research team has discovered the mechanism behind this phenomenon and published their findings in the journal "Circulation".

How can we use the knowledge gained so far to better overcome the COVID-19 crisis and prevent future pandemics? Two MDC labs are taking part in a collaborative Helmholtz project that aims to answer this question from an immunological, virological and economic perspective.

When the cells’ power plants don’t function properly, life expectancy is low. Otherwise, little is known about Leigh syndrome. Using organoids, researchers in Düsseldorf and Berlin have now created the first human model for studying this rare disease. They are presenting their work in “Nature Communications”.

MDC researchers used significantly fewer laboratory animals during the coronavirus pandemic in 2020 than in previous years. The MDC has now been awarded the “Exemplary Communications of Animal Research” seal for its transparency on the issue of animal experiments.

All living things are built from proteins. Biologist Matthias Selbach uses the technique of mass spectrometry to understand the various functions of proteins and to systematically hunt down those that cause – or can prevent – disease.

What side effects should I expect from the vaccines against the new SARS-CoV-2 coronavirus? Have they been developed too fast? To support a factual debate, our experts from the fields of immunology and RNA biology answered frequently asked questions.

Those who need to change their eating habits to normalise their blood pressure should start with a fast. In the journal “Nature Communications”, MDC and ECRC scientists explain why patients can use it as a tool to improve their health in the long term.

His career brought him to Montreal, Marrakech, Heidelberg, and Berlin. Detlev Ganten is a citizen of the world. His greatest impact has been in Berlin, where he founded the MDC, was the head of Charité, and initiated the World Health Summit. What motivates this determined fighter for science and global health?