The MDC Mission

The Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) carries out basic biomedical research with the aim of understanding the molecular basis of health and disease, and translating these findings as quickly as possible into clinical application. The research involves the diagnosis and treatment of diseases, as well as their prevention.

MDC 25 years

Research Highlights

Gut bacteria are sensitive to salt

Nature study shows: Salt reduces lactic acid bacteria in the gut whichs influences immune cells responsible for autoimmune diseases and hypertension. Probiotics ameliorate the symptoms in mice.


The logistics of neuronal messenger RNAs

Where proteins are localized within a cell is crucial to their proper function, especially in cells like neurons. It affects neuronal development and even learning and memory. A research team led by Marina Chekulaeva has for the first time systematically analyzed how this localization comes about. Their article appeared in Nature Communications.


Further research highlights


How the kidneys produce concentrated urine

When we drink little, we produce less urine. But how is this process regulated? An international team of scientists led by Prof. Kai Schmidt-Ott of the Max Delbrück Center for Molecular Medicine (MDC) has now shed light on how the kidneys concentrate urine.


Molecular Chaperones Shown to Assist in the Fight against Huntington Disease

Huntington’s disease is a neurodegenerative disease without a cure. It is always fatal. The disease is caused by a defect in the Huntingtin gene. Scientists recently discovered a natural mechanism, which not only suppresses the build-up of pathogenic amyloid fibrils but also disaggregates them.


Philipp Wahle awarded MDC PhD Prize of 2017

Philipp Wahle of the lab of Robert Zinzen developed a highly resolved virtual model of a fly embryo, which shows  which genes are active in which cell. He received the MDC PhD Prize at the annual Graduate Ceremony on November 24, 2017 for the paper in which he published these results. Two second-place publications were awarded […]


Further news on MDC Insights