Max Delbrück Center MDC - Max-Delbrück-Centrum für molekulare Medizin in der Helmholtz-Gemeinschaft

Our Research

Research at the Max Delbrück Center aims to elucidate the molecular mechanisms of health and disease, and translate those findings into medical practice.

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Data Science and Artificial Intelligence

Enabling multi-modal prediction from molecules to cohorts.

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Research Highlights

Our research teams publish around 450 specialist articles every year. Our research highlights can be found here, presented in a comprehensible format.

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Selection of research highlights
induced pluripotent stem cells in a pluripotency test

Research News & Events

Two people
Science

A jump-start for two spin-offs

This year, the Pre-GoBio program is supporting two planned spin-offs. Paul Schöpe aims to bring a drug targeting colorectal cancer metastases to market. And Ines Lahmann will further develop NMJCare, a model that can be used to test therapies for neuromuscular diseases.
Mina Gouti
Science

Professorship awarded to Mina Gouti

Mina Gouti has been awarded a professorship at Charité – Universitätsmedizin Berlin. The appointment will strengthen her pioneering organoid research at the Max Delbrück Center and deepen collaboration with clinicians to advance personalized medicine.
Ludwig Leif
Science

Leif Si-Hun Ludwig awarded professorship

Leif Si-Hun Ludwig has been awarded a prestigious Heisenberg professorship in stem cell dynamics and mitochondrial genomics by the the Berlin Institute of Health at Charité, a position funded by the German Research Foundation (DFG).
Blood
Science

A blood test to detect immune deficiency

Researchers at the Max Delbrück Center have developed a fast, cost-effective blood-based tool that can identify and classify immune deficiencies with high accuracy. The approach, published in “Nature Communications,” could help address long-standing gaps in diagnosing immune disorders.
Bavarian pine vole
Science

Helping to save an endangered species

Sebastian Diecke has won 200,000 euro grant to sequence the genome of the Bavarian pine vole, a mammal endemic to Germany that was once thought to be extinct. His lab will also explore stem cell approaches to support future captive breeding efforts.
Scientific image
Science

Reassessing how cells respond to drugs

Different drugs that bind to the same receptor in the cell membrane were long thought to activate cells in the same way. A study in “Nature,” however, suggests this understanding is too simplistic and highlights a way to develop drugs that are more precise and cause fewer side effects.
woman
Science

Moving biomedical research to the market

Discovery, invention and spin-offs – Nevine Shalaby, Head of Innovation & Entrepreneurship was interviewed by “Buch Inside” about the path from research to innovation. She discusses how her team supports marketable research discoveries made at the Max Delbrück Center.
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Our new Head of Communications

The Max Delbrück Center’s Communications and Marketing department has a new head: Tabea Rauscher has taken over the role from Jutta Kramm. With a passion for science and strategic communication, she is shaping the dialogue between research and society.
woman
Science

Agnieszka Rybak-Wolf wins Alzheimer‘s research grant

How do the ApoE4 gene variant and the herpes simplex virus work together to increase the risk of developing Alzheimer’s disease? Agnieszka Rybak-Wolf has been awarded a grant from Alzheimer Forschung Initiative to study the molecular interaction between the two risk factors.

All News & Events

Publications

CRISPR-MiX: a pooled single-stranded donor strategy to enhance HDR efficiency in human iPSCs

Molecular Therapy Nucleic Acids

Current treatment strategies for first relapse of high-risk neuroblastoma

European Journal of Cancer

FOXO1 re-expression with a dual-recombinase allele rescues class switching in germinal center B cells

Journal of Experimental Medicine

Pediatric and adult point of view on the gut-kidney axis in CKD

Pediatric Nephrology

All Publications