Max Delbrück Center MDC - Max-Delbrück-Centrum für molekulare Medizin in der Helmholtz-Gemeinschaft

Our Research

Research at the Max Delbrück Center aims to elucidate the molecular mechanisms of health and disease, and translate those findings into medical practice.

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Data Science and Artificial Intelligence

Enabling multi-modal prediction from molecules to cohorts.

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Research Highlights

Our research teams publish around 450 specialist articles every year. Our research highlights can be found here, presented in a comprehensible format.

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Selection of research highlights
induced pluripotent stem cells in a pluripotency test

Research News & Events

Person in the MRI scanner

New material boosts MRI image quality

MRI scans often struggle to capture clear images of deep or delicate tissues. Researchers at the Max Delbrück Center now report in “Advanced Materials” a new lightweight antenna that boosts image quality and may shorten scan times ¬– without changing existing MRI machines.
scientific image
Science

New Max Delbrück Center focus on bioengineering

Helmholtz-funded projects highlight a new focus at the Max Delbrück Center on biomedical engineering. By combining biomedicine, artificial intelligence, and engineering, basic research can be more quickly translated into therapies.
People on stage
Science

scienceCLASH podcast funded for a second season

ScienceCLASH, a podcast developed at the Gläsernes Labor, has won the MINT-EC School Award, which is sponsored by the Dr. Hans Riegel Foundation and comes with 7,000 euros in funding. A second season is already in the works – and researchers at the Max Delbrück Center are invited to participate.
Two people
Science

A jump-start for two spin-offs

This year, the Pre-GoBio program is supporting two planned spin-offs. Paul Schöpe aims to bring a drug targeting colorectal cancer metastases to market. And Ines Lahmann will further develop NMJCare, a model that can be used to test therapies for neuromuscular diseases.
Mina Gouti
Science

Professorship awarded to Mina Gouti

Mina Gouti has been awarded a professorship at Charité – Universitätsmedizin Berlin. The appointment will strengthen her pioneering organoid research at the Max Delbrück Center and deepen collaboration with clinicians to advance personalized medicine.
Ludwig Leif
Science

Leif Si-Hun Ludwig awarded professorship

Leif Si-Hun Ludwig has been awarded a prestigious Heisenberg professorship in stem cell dynamics and mitochondrial genomics by the the Berlin Institute of Health at Charité, a position funded by the German Research Foundation (DFG).
Blood
Science

A blood test to detect immune deficiency

Researchers at the Max Delbrück Center have developed a fast, cost-effective blood-based tool that can identify and classify immune deficiencies with high accuracy. The approach, published in “Nature Communications,” could help address long-standing gaps in diagnosing immune disorders.
Bavarian pine vole
Science

Helping to save an endangered species

Sebastian Diecke has won 200,000 euro grant to sequence the genome of the Bavarian pine vole, a mammal endemic to Germany that was once thought to be extinct. His lab will also explore stem cell approaches to support future captive breeding efforts.
Scientific image
Science

Reassessing how cells respond to drugs

Different drugs that bind to the same receptor in the cell membrane were long thought to activate cells in the same way. A study in “Nature,” however, suggests this understanding is too simplistic and highlights a way to develop drugs that are more precise and cause fewer side effects.

All News & Events

Publications

Liver-X-receptor agonism enhances T cell priming and activation to promote anti-tumor immunity

Journal of Experimental Medicine

Longitudinal effects of dimethyl fumarate on patient-reported outcome measures in multiple sclerosis: treatment satisfaction, quality of life, depressive symptoms, sleep, and work productivity

Journal of Clinical Neuroscience

Conservation and specificity in Bacillus biofilm dynamics: on structure and function of B. cereus Camelysins

Journal of Molecular Biology

CRISPR-MiX: a pooled single-stranded donor strategy to enhance HDR efficiency in human iPSCs

Molecular Therapy Nucleic Acids

All Publications