Max Delbrück Center MDC - Max-Delbrück-Centrum für molekulare Medizin in der Helmholtz-Gemeinschaft

Our Research

Research at the Max Delbrück Center aims to elucidate the molecular mechanisms of health and disease, and translate those findings into medical practice.

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Corona research

Infection with SARS-CoV-2 affects not only the respiratory system, but the entire body – and we still have a lot to learn. Our research at the Max Delbrück Center will improve our ability to deal with the coronavirus in the future.

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Research Highlights

Our research teams publish around 450 specialist articles every year. Our research highlights can be found here, presented in a comprehensible format.

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Selection of research highlights
induced pluripotent stem cells in a pluripotency test

Research News & Events

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Science

Tackling rare kidney diseases

Michael Bader’s lab and six other European research groups are working to develop new methods to diagnose and monitor the progression of two kidney diseases. Both disorders are caused by an overactive unit of the body’s immune system. The researchers will receive €1.9 million for the project.
Sarah Hedtrich
Science

Welcome, Sarah Hedtrich!

Sarah Hedtrich heads a guest group at the Max Delbrück Center. The Johanna Quandt Professor at the Berlin Institute of Health at Charité (BIH) is working on organ-on-a-chip models to develop new treatment options for rare hereditary and inflammatory skin and lung diseases.
Michael Robson
Science

Unwinding clues to disease in DNA’s 3D structure

The Robson lab at the Max Delbrück Center will be studying how the 3D structure of chromatin controls genes during development and in disease. Leveraging novel single cell methods, they will look at muscular dystrophies and retinal disease. Both seem to be linked to mutations that disrupt the function of non-coding DNA.
Naked Mole Rats
Institute & Campus

Communicating research in tandem

Two science communications projects of the Max Delbrück Center have received funding from the Stiftung Charité. About 100,000 Euro will go to Gary Lewin and illustrator Kat Menschik for a book on unusual animals in research, and to Russ Hodge and Jennifer von Schlichting for a board game on gene expression.
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Science

How diseases begin in the gut

A Berlin-based team led by ECRC researcher Dominik N. Müller is analyzing how inflammation of the intestinal mucosa affects blood vessels. They are still looking for study participants – especially people with inflammatory bowel diseases, multiple sclerosis, high blood pressure and diabetes.
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Science

Protecting and repairing neurons

She wants to uncover the mechanisms behind inflammatory neurodegenerative diseases, while also developing new therapeutic approaches and testing them in clinical trials. With these goals in mind, Frederike Cosima Oertel is launching the Translational Neuroimmunology Lab at the ECRC.
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Institute & Campus

What are you reading, Ms Cipińska?

Marta Cipińska coordinates a PhD exchange program between New York University (NYU) and MDC-BIMSB that trains the next generation of systems biologists. No longer a scientist, she has replaced PubMed with browsing the shelves of her local bookstore – and found “Moonwalking with Einstein.”
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Healthy kidneys despite hypertension

A mutation that causes severe hypertension also protects the kidneys from being damaged, reports a team led by Enno Klußmann of the Max Delbrück Center and the DZHK in “Kidney International”. The researchers are now exploring how the effects of the mutated gene can be used therapeutically.
Anti-CXCR5 CAR-T cells (green) attack lymphoma cells (magenta) within the stroma cell network of the B cell follicle (light blue).

€4.6 million for a novel CAR T-cell therapy

While CAR-T cells have proven successful in treating certain types of leukemia and lymphoma, these immunotherapies can become even more effective. A clinical trial run by Charité and the Max Delbrück Center has been awarded a grant of several million euros to test a new approach.

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Publications

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