Max Delbrück Center MDC - Max-Delbrück-Centrum für molekulare Medizin in der Helmholtz-Gemeinschaft

Our Research

Research at the Max Delbrück Center aims to elucidate the molecular mechanisms of health and disease, and translate those findings into medical practice.

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Data Science and Artificial Intelligence

Enabling multi-modal prediction from molecules to cohorts.

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Research Highlights

Our research teams publish around 450 specialist articles every year. Our research highlights can be found here, presented in a comprehensible format.

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Selection of research highlights
induced pluripotent stem cells in a pluripotency test

Research News & Events

Bavarian pine mole
Science

Helping to save an endangered species

Sebastian Diecke has won 200,000 euro grant to sequence the genome of the Bavarian pine vole, a mammal endemic to Germany that was once thought to be extinct. His lab will also explore stem cell approaches to support future captive breeding efforts.
Scientific image
Science

Reassessing how cells respond to drugs

Different drugs that bind to the same receptor in the cell membrane were long thought to activate cells in the same way. A study in “Nature,” however, suggests this understanding is too simplistic and highlights a way to develop drugs that are more precise and cause fewer side effects.
woman
Science

Moving biomedical research to the market

Discovery, invention and spin-offs – Nevine Shalaby, Head of Innovation & Entrepreneurship was interviewed by “Buch Inside” about the path from research to innovation. She discusses how her team supports marketable research discoveries made at the Max Delbrück Center.
woman

Our new Head of Communications

The Max Delbrück Center’s Communications and Marketing department has a new head: Tabea Rauscher has taken over the role from Jutta Kramm. With a passion for science and strategic communication, she is shaping the dialogue between research and society.
woman
Science

Agnieszka Rybak-Wolf wins Alzheimer‘s research grant

How do the ApoE4 gene variant and the herpes simplex virus work together to increase the risk of developing Alzheimer’s disease? Agnieszka Rybak-Wolf has been awarded a grant from Alzheimer Forschung Initiative to study the molecular interaction between the two risk factors.
man
Science

In Memoriam: Peer Bork

We mourn the sudden unexpected loss of Peer Bork, a formative figure who helped shape the center’s intellectual spirit and commitment to innovative life science. Bork went on to build an extraordinary international career, influencing modern biology far beyond Berlin.
Nikolaus Rajewsky und Leif Sander
Science

A new opportunity for Berlin

The Einstein Center for Early Disease Interception has been funded with six million euros. In an interview, Nikolaus Rajewsky and Leif Erik Sander, both spokespeople of the center, explain why new technologies and cross-institutional collaboration will make disease prevention in the future possible.
People talking
Science

Bridging science and business

During the Predictive Systems Medicine Partnering Event at the Max Delbrück Center, researchers and industry representatives shared insights and explored commercialization opportunities – advancing our mission to turn discovery into real-world health impact.
Scientific image
Science

Berlin joins national genome data network

The Max Delbrück Center and Berlin Institute of Health at Charité have joined a national network of six Genome Data Centers and the German Human Genome-Phenome Archive, adding Berlin as an operational data hub for genomic medicine and omics-based research.
Ines Lahmann and Mina Gouti
Science

A spin-off targeting neuromuscular disorders

A team led by Mina Gouti has developed a stem cell-based model that enables researchers to test new drugs to treat neuromuscular diseases and to refine existing therapies. The project, called NMJCare, was named one of the top ten ideas in the national Science4Life start-up competition.

All News & Events

Publications

CRISPR-MiX: a pooled single-stranded donor strategy to enhance HDR efficiency in human iPSCs

Molecular Therapy Nucleic Acids

FOXO1 re-expression with a dual-recombinase allele rescues class switching in germinal center B cells

Journal of Experimental Medicine

Pediatric and adult point of view on the gut-kidney axis in CKD

Pediatric Nephrology

Patterns and trajectories of behavioral and neuropsychiatric symptoms in frontotemporal dementia and primary progressive aphasia

Neurology

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