MDC Berlin

Ein hochrangiges internationales Panel wird am 3. März 2021 die neueste Forschung zur Pandemie, zu Coronaviren und ihren Varianten, zu Impfstoffen und Therapien vorstellen. Das virtuelle Symposium zu COVID-19 haben das MDC und die Initiative „Immunologie und Inflammation “ der Helmholtz-Gemeinschaft organisiert.

A year ago, BIH , MDC and Charité launched the joint research focus "Single Cell Approaches for Personalised Medicine". Its aim is to use innovative single cell technologies to answer clinical questions. This aspiration will be put into practice by four new junior research groups, which have now started.

Some converse in Creole, while others speak Scots, but it’s not only humans who can be identified by the diversity of language they speak. Naked mole-rats have their own dialects, too. Shared dialect also strengthens cohesion within a colony, a team led by MDC researcher Gary Lewin reports in the current "Science" cover story.

What side effects should I expect from the vaccines against the new SARS-CoV-2 coronavirus? Have they been developed too fast? To support a factual debate, our experts from the fields of immunology and RNA biology answered frequently asked questions.

Anton Henssen of the ECRC has been awarded the Kind Philipp Award for Pediatric Oncology Research for his study of ring-shaped DNA and its significance in the development of childhood neuroblastoma. A publication in the scientific journal Nature Genetics was decisive for this award.

Its official description, a “specialized science library serving the staff of the MDC,” sounds as dry as a dusty bookshelf. What else does the MDC library have to offer? We answer that question in an interview with Wolf Schröder-Barkausen, in another installment of our series “We at the MDC.”

Colon cancer stem cells have one weak spot: the enzyme Mll1. An MDC team led by Walter Birchmeier has now shown in Nature Communications that blocking this protein prevents the development of new tumors in the body.

In order for the human immune system to effectively fight off pathogens, B cells need to smash up and reassemble their own DNA. Michela Di Virgilio searches for factors controlling this important process, which also have crucial implications for our predisposition to cancer.

A muscle fiber consists of just one cell, but many nuclei. A team at the MDC led by Professor Carmen Birchmeier has now shown just how varied these nuclei are. The study, which has been published in Nature Communications, can help us better understand muscle diseases such as Duchenne muscular dystrophy.