Scientific Publications

Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19

M. Essex
B.L. Millet Pascual-Leone
U. Löber
M. Kuhring
B. Zhang
U. Brüning
R. Fritsche-Guenther
M. Krzanowski
F. Fiocca Vernengo
S. Brumhard
I. Röwekamp
A.A. Bielecka
T.R. Lesker
E. Wyler
M. Landthaler
A. Mantei
C. Meisel
S. Caesar
C. Thibeault
V.M. Corman
L. Marko
N. Suttorp
T. Strowig
F. Kurth
L.E. Sander
Y. Li
J.A. Kirwan
S.K. Forslund
B. Opitz

Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin

O. Al-Diab
C. Sünkel
E. Blanc
R.A. Catar
M.I. Ashraf
H. Zhao
P. Wang
M.M. Rinschen
R. Fritsche-Guenther
F. Grahammer
S. Bachmann
D. Beule
J.A. Kirwan
N. Rajewsky
T.B. Huber
D. Gürgen
A. Kusch

Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in severe COVID-19

M. Essex
B.M. Pascual-Leone
U. Löber
M. Kuhring
B. Zhang
U. Bruening
R. Fritsche-Guenther
M. Krzanowski
F.F. Vernengo
S. Brumhard
I. Röwekamp
A.A. Bielecka
T.R. Lesker
E. Wyler
M. Landthaler
A. Mantei
C. Meisel
S. Caesar
C. Thiebeault
V. Corman
L. Marko
N. Suttorp
T. Strowig
F. Kurth
L.E. Sander
Y. Li
J.A. Kirwan
S.K. Forslund
B. Opitz

March 30, 2024 / Nat Commun

Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung

P.J. Dörner
H. Anandakumar
I. Röwekamp
F. Fiocca Vernengo
B. Millet Pascual-Leone
M. Krzanowski
J. Sellmaier
U. Brüning
R. Fritsche-Guenther
L. Pfannkuch
F. Kurth
M. Milek
V. Igbokwe
U. Löber
B. Gutbier
M. Holstein
G.A. Heinz
M.F. Mashreghi
L.N. Schulte
A.B. Klatt
S. Caesar
S.M. Wienhold
S. Offermanns
M. Mack
M. Witzenrath
S. Jordan
D. Beule
J.A. Kirwan
S.K. Forslund
N. Wilck
H. Bartolomaeus
M.M. Heimesaat
B. Opitz

Mechanical heterogeneity in a soft biomaterial niche controls BMP2 signaling

E. Brauer
A. Herrera
R. Fritsche-Guenther
S. Görlitz
H. Leemhuis
P. Knaus
J.A. Kirwan
G.N. Duda
A. Petersen

Passenger gene coamplifications create collateral therapeutic vulnerabilities in cancer

Y. Bei
Luca Brame
M. Kirchner
R. Fritsche-Guenther
S. Kunz
A. Bhattacharya
M.C. Rusu
D. Gürgen
F.P.B. Dubois
J.K.C. Köppke
J. Proba
N. Wittstruck
O.A. Sidorova
R. Chamorro González
H. Dorado Garcia
L. Brückner
R. Xu
M. Giurgiu
E. Rodriguez-Fos
Q. Yu
B. Spanjaard
R.P. Koche
C.A. Schmitt
J.H. Schulte
A. Eggert
K. Haase
J. Kirwan
A.I. Hagemann
P. Mertins
J.R. Dörr
A.G. Henssen

Macrocephaly and digital anomalies expand the phenotypic spectrum of PGAP2 variants in hyperphosphatasia with impaired intellectual development syndrome 3 (HPMRS3)

S. Susgun
A. Ben-Mahmoud
F. Rüschendorf
B. Ku
S.I. Hussain
S. Schulz
O. Puk
S. Biskup
J.D.J. Labonne
D.W. Don
V. Gupta
T.I. Choi
S. Khan
N. Wasif
Y. Lacassie
L.C. Layman
S.A. Ugur Iseri
C.H. Kim
H.G. Kim

Comparing the extraction performance in mouse plasma of different biphasic methods for polar and nonpolar compounds

F. Gutmann
R. Fritsche-Guenther
D.B. Dias
J.A. Kirwan

Promising results of a clinical feasibility study: CIRBP as a potential biomarker in pediatric cardiac surgery

J. Lücht
R. Seiler
A.L. Herre
L. Brankova
R. Fritsche-Guenther
J. Kirwan
D. Huscher
H. Münzfeld
F. Berger
J. Photiadis
G. Tong
K.R.L. Schmitt

Murine susceptibility to Chagas' disease maps to chromosomes 5 and 17

S.E. Graefe
B.S. Meyer
B. Mueller-Myhsok
F. Rueschendorf
C. Drosten
T. Laue
C. Steeg
P. Nuernberg
B. Fleischer