Scientific Publications

Immune response and metastasis-links between the metastasis driver MACC1 and cancer immune escape strategies

S. Torke
W. Walther
U. Stein

MACC1 regulates LGR5 to promote cancer stem cell properties in colorectal cancer

M. Erdem
K.H. Lee
M. Hardt
J.L. Regan
D. Kobelt
W. Walther
M. Mokrizkij
C. Regenbrecht
U. Stein

Impact of the PI3Kalpha inhibitor alpelisib on everolimus resistance and somatostatin receptor expression in an orthotopic pancreatic NEC xenograft mouse model

A.M. Mohan
S. Prasad
F. Schmitz-Peiffer
C. Lange
M. Lukas
E.J. Koziolek
J. Albrecht
D. Messroghli
U. Stein
M. Ilmer
K. Wang
L. Schober
A. Reul
J. Maurer
J. Friemel
A. Weber
R.A. Zuellig
C. Hantel
R. Fritsch
M. Reincke
K. Pacak
A.B. Grossman
C.J. Auernhammer
F. Beuschlein
W. Brenner
N. Beindorff
S. Nölting

GIPC1 regulates MACC1-driven metastasis

F. Siegel
H. Schmidt
M. Juneja
J. Smith
P. Herrmann
D. Kobelt
K. Sharma
I. Fichtner
W. Walther
G. Dittmar
R. Volkmer
F.G. Rathjen
P.M. Schlag
U. Stein

H4K20me3 upregulated by reactive oxygen species is associated with tumor progression and poor prognosis in patients with hepatocellular carcinoma

S. Phoyen
A. Sanpavat
C. Ma-on
U. Stein
N. Hirankarn
P. Tangkijvanich
D. Jindatip
P. Whongsiri
C. Boonla

Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis

S. Yan
P.C. Schöpe
J. Lewis
K. Putzker
U. Uhrig
E. Specker
J.P. von Kries
P. Lindemann
A. Omran
H.E. Sanchez-Ibarra
A. Unger
M.L. Zischinsky
B. Klebl
W. Walther
M. Nazaré
D. Kobelt
U. Stein

Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators

J. Kühnisch
S. Theisen
J. Dartsch
R. Fritsche-Guenther
M. Kirchner
B. Obermayer
A. Bauer
A.K. Kahlert
M. Rothe
D. Beule
A. Heuser
P. Mertins
J.A. Kirwan
N. Berndt
C.A. MacRae
N. Hubner
S. Klaassen

November 07, 2023 / Nat Commun

Transcriptional reprogramming by mutated IRF4 in lymphoma

N. Schleussner
P. Cauchy
V. Franke
M. Giefing
O. Fornes
N. Vankadari
S.A. Assi
M. Costanza
M.A. Weniger
A. Akalin
I. Anagnostopoulos
T. Bukur
M.G. Casarotto
F. Damm
O. Daumke
B. Edginton-White
J.C.M. Gebhardt
M. Grau
S. Grunwald
M.L. Hansmann
S. Hartmann
L. Huber
E. Kärgel
S. Lusatis
D. Noerenberg
N. Obier
U. Pannicke
A. Fischer
A. Reisser
A. Rosenwald
K. Schwarz
S. Sundararaj
A. Weilemann
W. Winkler
W. Xu
G. Lenz
K. Rajewsky
W.W. Wasserman
P.N. Cockerill
C. Scheidereit
R. Siebert
R. Küppers
R. Grosschedl
M. Janz
C. Bonifer
S. Mathas

Linee guida ESC 2023 per il trattamento delle cardiomiopatie [2023 ESC Guidelines for the management of cardiomyopathies]

E. Arbelo
A. Protonotarios
J.R. Gimeno
E. Arbustini
R. Barriales-Villa
C. Basso
C.R. Bezzina
E. Biagini
N.A. Blom
R.A. de Boer
T. De Winter
P.M. Elliott
M. Flather
P. Garcia-Pavia
K.H. Haugaa
J. Ingles
R.O. Jurcut
S. Klaassen
G. Limongelli
B. Loeys
J. Mogensen
I. Olivotto
A. Pantazis
S. Sharma
J.P. Van Tintelen
J.S. Ware
J.P. Kaski

A computational model of the DNA damage-induced IKK/ NF-κB pathway reveals a critical dependence on irradiation dose and PARP-1

F. Konrath
M. Willenbrock
D. Busse
C. Scheidereit
J. Wolf