Scientific Publications

Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation

GPER activation attenuates cardiac dysfunction by upregulating the SIRT1/3-AMPK-UCP2 pathway in postmenopausal diabetic rats

Discovery of a non-canonical GRHL1 binding site using deep convolutional and recurrent neural networks

Structure-based design of xanthine-imidazopyridines and -imidazothiazoles as highly potent and in vivo efficacious tryptophan hydroxylase inhibitors

Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease

TapA acts as specific chaperone in TasA filament formation by strand complementation

Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D

Lack of evidence for participation of TMEM150C in sensory mechanotransduction

August 25, 2022 / J Med Chem

Structure-based design of xanthine-benzimidazole derivatives as novel and potent tryptophan hydroxylase inhibitors

Editorial: Sexual dimorphism in biomedical research and its therapeutic implications