Scientific Publications

Visualization of class A GPCR oligomerization by image-based fluorescence fluctuation spectroscopy

Determination of G-protein-coupled receptor oligomerization by molecular brightness analyses in single cells

A versatile sub-nanomolar fluorescent ligand enables NanoBRET binding studies and single-molecule microscopy at the histamine H(3) receptor

Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors

Vibrational spectroscopy as a powerful tool for follow-up immunoadsorption therapy treatment of dilated cardiomyopathy - a case report

November 17, 2020 / Proc Natl Acad Sci U S A

Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists

Molecular details of dimerization kinetics reveal negligible populations of transient µ-opioid receptor homodimers at physiological concentrations.

Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling