Scientific Publications

Cardiac signaling: cellular, molecular and clinical aspects

M. Gotthardt
K. Raddatz

Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

P. Jansen
K. Giehl
J.R. Nyengaard
K. Teng
O. Lioubinski
S.S. Sjoegaard
T. Breiderhoff
M. Gotthardt
F. Lin
A. Eilers
C.M. Petersen
G.R. Lewin
B.L. Hempstead
T.E. Willnow
A. Nykjaer

Muscle atrophy in titin M-line deficient mice

J. Peng
K. Raddatz
S. Labeit
H. Granzier
M. Gotthardt

M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere

S. Weinert
N. Bergmann
X. Luo
B. Erdmann
M. Gotthardt

September 07, 2005 / Proc Natl Acad Sci U S A

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

O.M. Andersen
J. Reiche
V. Schmidt
M. Gotthardt
R. Spoelgen
J. Behlke
C.A.F. von Arnim
T. Breiderhoff
P. Jansen
X. Wu
K.R. Bales
R. Cappai
C.L. Masters
J. Gliemann
E.J. Mufson
B.T. Hyman
S.M. Paul
A. Nykjaer
T.E. Willnow

Cardiac hypertrophy and reduced contractility in hearts deficient in the titin kinase region

J. Peng
K. Raddatz
J.D. Molkentin
Y. Wu
S. Labeit
H. Granzier
M. Gotthardt

Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy

M.H. Radke
J. Peng
Y. Wu
M. McNabb
O.L. Nelson
H. Granzier
M. Gotthardt

Functional genomics of chicken, mouse, and human titin supports splice diversity as an important mechanism for regulating biomechanics of striated muscle

H. Granzier
M. Radke
J. Royal
Y. Wu
T.C. Irving
M. Gotthardt
S. Labeit

Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction

H.L. Granzier
M.H. Radke
J. Peng
D. Westermann
O.L. Nelson
K. Rost
N.M. King
Q. Yu
C. Tschoepe
M. McNabb
D.F. Larson
S. Labeit
M. Gotthardt

Altered contractility of skeletal muscle in mice deficient in titin's M-band region

C.A. Ottenheijm
C. Hidalgo
K. Rost
M. Gotthardt
H. Granzier