16th Berlin Summer Meeting: The MDC celebrates 15 years of BIMSB
2023 marks the 15-year anniversary of the Berlin Institute for Medical Systems Biology (BIMSB), founded in 2008 as part of the Max Delbrück Center. To honor this milestone, our annual Berlin Summer Meeting Meeting – which, along with the BIMSB, has also been established in 2008 – will be held under the motto “The MDC celebrates 15 years of BIMSB”. The meeting is jointly organized by the Topic 1 Faculty.
The Berlin Summer Meeting: Computational and Experimental Biology Meet brings together scientists at the interface of experimental molecular biology and computational biology and connects young researchers with top-level senior scientists. This year’s Berlin Summer Meeting will showcase exciting new developments in the field of systems biology, work by BIMSB alumni as well as science which has been highly impactful for us – and we are excited to be hosting a fantastic selection of international experts!
To reflect the founding and early years of the BIMSB on the Campus Buch and the subsequent move to a dedicated research building in the center of Berlin, the first day of the meeting will be held in the Max Delbrück Communications Center in Berlin-Buch, and the second day will take place in the centrally located Langenbeck-Virchow-Haus. The meeting will conclude with a retrospective 15 years MDC-BIMSB with evening reception at the MDC location in Berlin-Mitte (MDC-BIMSB research building).
If you require childcare, please let us know no later than Aug 28th via E-mail: BIMSB.Events@mdc-berlin.de
Early Bird End: August 15, 2023
Registration Fee Overview
| Full registration fee (early) | 350,00 € |
| Full registration fee (late) | 450,00 € |
| External students | 200,00 € |
| MDC employees | 200,00 € |
| MDC Students | 100,00 € |
Venue
MDC (Buch) & Langenbeck-Virchow-Haus
Robert-Rössle-Straße 10 bzw. Luisenstraße 58/59
13125 Berlin
Germany
Time
Program
- Wednesday, September 6, 2023
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MDC.C Max Delbrück Communications Center,
Campus Buch, Robert-Rössle-Str. 10, 13125 Berlin
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9:00 am – 9:15 am Welcome address by Maike Sander and Nikolaus Rajewsky
Session 1 Host: Nikolaus Rajewsky
9:15 am – 10:00 am Bernd Bodenmiller (University of Zurich, ETH Zurich, Switzerland)
tba
10:00 am – 10:15 am Nora Fresmann (MDC-BIMSB, Berlin, Germany)
Cause and consequence of intra- and inter-tumor heterogeneity in zebrafish models of neuroblastoma
10:15 am – 11:00 am Hans Clevers (Roche Pharma Research and Early Development Roche Innovation Center Basel, Switzerland)
Organoids to model human disease
11:00 am – 11:30 am Coffee break
Session 2 Host: Nikolaus Rajewsky: ((MDC-BIMSB Alumni Session)
11:30 am – 11:50 pm Pinar Önal (Bilkent University, Ankara, Turkey)
Evolutionary dynamics of a robust transcriptional network
11:50 am – 12:10 pm Baris Tursun (Universität Hamburg, Germany)
A reprogrammed worms perspective on BIMSB
12:10 pm – 12:30 pm Elena Torlai Triglia (Broad Institute, Cambridge, MA, USA)
Identifying molecular determinants of cancer phenotypes with edited human cell models
12:30 pm – 12:50 pm Lea Gregersen (University of Copenhagen, Denmark)
Oxidative stress triggers a unique and transient dynamic transcriptional response
12:50 pm – 1:10 pm Mathias Munschauer (Helmholtz Institute for RNA-based Infection Research, Würzburg, Germany)
The host protein SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis
1:10 pm – 3:00 pm Lunch & Poster session
Session 3 Host: Markus Landthaler
3:00 pm – 3:45 pm Dominic Grün (University of Würzburg, Germany)
Reconstructing cell fate decision in time and space
3:45 pm – 4:00 pm Till Schwämmle (Max Planck Institute for Molecular Genetics, Berlin, Germany)
Zic3 and Otx2 link Xist activation to the formative pluripotency network
4:00 pm – 4:15 pm Lisa Buchauer (Charité - Universitätsmedizin Berlin, Germany / Weizmann Institute of Science, Rehovot, Israel)
Spatial discordances between mRNAs and proteins in the intestinal epithelium
4:15 pm – 5:00 pm Gene Yeo (University of California, San Diego, CA, USA)
RNA binding protein networks in health and disease
- Thursday, September 7, 2023
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Langenbeck-Virchow-Haus, Luisenstr. 58/59, 10117 Berlin
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Session 4 Host: Ana Pombo
9:00 am – 9:45 am Patrick Cramer (MPI for Multidisciplinary Sciences, Göttingen, Germany)
New insights into transcription regulation
9:45 am – 10:00 am Tancredi Pentimalli (MDC-BIMSB, Berlin, Germany)
3D molecular reconstruction of a human tumor at single-cell resolution reveals invasion dynamics and predicts mechanism-based, personalized therapeutic targets10:00 am – 10:15 am Mikaela Behm (DKFZ, Heidelberg, Germany)
An interactive cellular ecosystem blocks epithelial transformation in naked mole-rat10:15 am – 11:00 am Stephan Preibisch (Janelia Research Campus, Ashburn, VA, USA)
Peta-scale microscopy – challenges, solutions and possibilities
11:00 – 11:30 Coffee break
Session 5 Host: Ashley Sanders
11:30 am – 12:15 am Nada Jabado (McGill University Health Centre, Montreal, Canada)
Oncohistone in disease: from cancer to neurodegeneration and beyond12:15 pm – 12:30 pm Max Trauernicht (Netherlands Cancer Institute, Amsterdam / Oncode Institute, Utrecht, the Netherlands)
Multiplexed detection of transcription factor activity12:30 pm – 12:45 pm Andréa Willemin (MDC-BIMSB, Berlin, Germany)
A GAM-based approach to explore the contribution of proteins or PTMs to 3D genome folding and cellular state transitions
12:45 am – 1:30 pm Stein Aerts (KU Leuven Center for Human Genetics and the VIB Center Disease Research, Belgium)
Single-cell driven enhancer modelling and design
1:30 pm Group photo
1:30 pm – 3:00 pm Lunch break
Session 6 Host: Stefanie Grosswendt3:00 pm – 3:45 pm Amos Tanay (Weizmann Institute of Science, Rehovot, Israel)
Profiling and modelling the blood to understand disease progression3:45 pm – 4:30 pm Tuuli Lappalainen (New York Genome Center, New York City, NY, USA, and KTH Royal Institute of Technology and SciLifeLab, Stockholm, Sweden)
Genetic effects on gene expression dosage underlying cellular and physiological phenotypes4:30 pm – 5:15 pm Sara Wickström (MPI for Molecular Biomedicine, Münster, Germany)
Coordination of cell states and tissue architecture by mechanical forces
5:15 pm Closing remarks
5:30 pm Reception, MDC-BIMSB, Hannoversche Str. 28, 10115 Berlin (5 min walking distance from the meeting venue)
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