Wissenschaftliche Publikationen | Max Delbrück Center

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September 2024 / Bioinformatics

Metadata-guided feature disentanglement for functional genomics

A. Rakowski
R. Monti
V. Huryn
M. Lemanczyk
U. Ohler
C. Lippert

29. Juli 2024 / Plant J

MatK impacts differential chloroplast translation by limiting spliced tRNA-K(UUU) abundance

J.M. Muino
H. Ruwe
Y. Qu
S. Maschmann
W. Chen
R. Zoschke
U. Ohler
K. Kaufmann
C. Schmitz-Linneweber

08. Juli 2024 / Nucleic Acids Res

Liam tackles complex multimodal single-cell data integration challenges

P. Rautenstrauch
U. Ohler

08. Juni 2024 / Cancer Gene Ther

Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia

L.H. Mochmann
D. Treue
M. Bockmayr
P. Silva
C. Zasada
G. Mastrobuoni
S. Bayram
M. Forbes
P. Jurmeister
S. Liebig
O. Blau
K. Schleich
B. Splettstoesser
T.M. Nordmann
E.K. von der Heide
K. Isaakidis
V. Schulze
C. Busch
H. Siddiq
C. Schlee
S. Hester
L. Fransecky
M. Neumann
S. Kempa
F. Klauschen
C.D. Baldus

Juni 2024 / Genes

A mouse model of X-linked chronic granulomatous disease for the development of CRISPR/Cas9 gene therapy

S. Sevim-Wunderlich
T. Dang
J. Rossius
F. Schnütgen
R. Kuehn

Mai 2024 / Cancers

L-glyceraldehyde inhibits neuroblastoma cell growth via a
multi-modal mechanism on metabolism and Signaling

M. Forbes
R. Kempa
G. Mastrobuoni
L. Rayman
M. Pietzke
S. Bayram
B. Arlt
A. Spruessel
H.E. Deubzer
S. Kempa

12. April 2024 / Sci Immunol

Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation

I. Tiniakou
P.F. Hsu
L.S. Lopez-Zepeda
G. Garipler
E. Esteva
N.M. Adams
G. Jang
C. Soni
C.M. Lau
F. Liu
A. Khodadadi-Jamayran
T.C. Rodrick
D. Jones
A. Tsirigos
U. Ohler
M.T. Bedford
S.D. Nimer
V. Kaartinen
E.O. Mazzoni
B. Reizis

29. Februar 2024 / BMJ Open Respir Res

Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters

L.G. Teixeira Alves
M. Baumgardt
C. Langner
M. Fischer
J. Maria Adler
J. Bushe
T.C. Firsching
G. Mastrobuoni
J. Grobe
K. Hoenzke
S. Kempa
A.D. Gruber
A.C. Hocke
J. Trimpert
E. Wyler
M. Landthaler

08. Januar 2024 / Front Cardiovasc Med

Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice

N. Dörmann
E. Hammer
K. Struckmann
J. Rüdebusch
K. Bartels
K. Wenzel
J. Schulz
S. Gross
S. Schwanz
E. Martin
B. Fielitz
C. Pablo Tortola
A. Hahn
A. Benkner
U. Völker
S.B Felix
J. Fielitz

04. Dezember 2023 / J Cell Biol

Stress-induced nuclear speckle reorganization is linked to activation of immediate early gene splicing

H.M. Sung
J. Schott
P. Boss
J.A. Lehmann
M.R. Hardt
D. Lindner
J. Messens
I. Bogeski
U. Ohler
G. Stoecklin