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in Cell Stem Cell

Human iPSC-derived neural progenitors are an effective drug discovery model for neurological mtDNA disorders

  • C. Lorenz
  • P. Lesimple
  • R. Bukowiecki
  • A. Zink
  • G. Inak
  • B. Mlody
  • M. Singh
  • M. Semtner
  • N. Mah
  • K. Auré
  • M. Leong
  • O. Zabiegalov
  • E.M. Lyras
  • V. Pfiffer
  • B. Fauler
  • J. Eichhorst
  • B. Wiesner
  • N. Huebner
  • J. Priller
  • T. Mielke
  • D. Meierhofer
  • Z. Izsvák
  • J.C. Meier
  • F. Bouillaud
  • J. Adjaye
  • M. Schuelke
  • E.E. Wanker
  • A. Lombès
  • A. Prigione
in Proc Natl Acad Sci U S A

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line

  • V.T. Chu
  • R. Graf
  • T. Wirtz
  • T. Weber
  • J. Favret
  • X. Li
  • K. Petsch
  • N.T. Tran
  • M.H. Sieweke
  • C. Berek
  • R. Kühn
  • K. Rajewsky
in Biol Sex Differ

Reduction of apoptosis and preservation of mitochondrial integrity under ischemia/reperfusion injury is mediated by estrogen receptor β

  • C. Schubert
  • V. Raparelli
  • C. Westphal
  • E. Dworatzek
  • G. Petrov
  • G. Kararigas
  • V. Regitz-Zagrosek
in Proc Natl Acad Sci U S A

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells

  • E. Derudder
  • S. Herzog
  • V. Labi
  • T. Yasuda
  • K. Köchert
  • M. Janz
  • A. Villunger
  • M. Schmidt-Supprian
  • K. Rajewsky
in Cereb Cortex

Identification of parvalbumin interneurons as cellular substrate of fear memory persistence

  • G. Caliskan
  • I. Mueller
  • M. Semtner
  • A. Winkelmann
  • A.S. Raza
  • J.O. Hollnagel
  • A. Roesler
  • U. Heinemann
  • O. Stork
  • J.C. Meier
in Nature

FOXO1 couples metabolic activity and growth state in the vascular endothelium

  • K. Wilhelm
  • K. Happel
  • G. Eelen
  • S. Schoors
  • M.F. Oellerich
  • R. Lim
  • B. Zimmermann
  • I.M. Aspalter
  • C.A. Franco
  • T. Boettger
  • T. Braun
  • M. Fruttiger
  • K. Rajewsky
  • C. Keller
  • J.C. Brüning
  • H. Gerhardt
  • P. Carmeliet
  • M. Potente
in Nat Immunol

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers

  • D.P. Calado
  • Y. Sasaki
  • S.A. Godinho
  • A. Pellerin
  • K. Köchert
  • B.P. Sleckman
  • I.M. de Alboran
  • M. Janz
  • S. Rodig
  • K. Rajewsky