Experimental and Clinical Research Center
Lindenberger Weg 80
13125 Berlin
Building 49
© Hedwig Deubzer, ECRCV, Charite
Deubzer Lab
Profile
My lab pursues Translational Neuroblastoma Research.
We focus on mechanisms that drive uncontrolled proliferation, mediate therapy resistance, block neuronal differentiation and promote the invasion-metastasis cascade by applying systems biology concepts to a solid basis of high-throughput molecular profiling data.
We focus on mechanisms that drive uncontrolled proliferation, mediate therapy resistance, block neuronal differentiation and promote the invasion-metastasis cascade by applying systems biology concepts to a solid basis of high-throughput molecular profiling data.
Preclinical neuroblastoma models include patient-derived 3D cell cultures and xenografts in mice. All research projects are directed towards providing a basis for decision-making in the rational development of improved diagnostics and novel therapeutics for high-risk neuroblastoma patients.
Further information could be found at the Charité website of the group at the Department of Pediatrics, Division of Oncology and Hematology.
Team
Group Leader
Prof. Dr. Hedwig Deubzer
Scientist
Dr. Maddalena Grimaldi
Technical Assistant
Jeannette Mothes