Header Deubzer

Deubzer Lab

Epigenetic Modifications in Neuroblastoma


My lab pursues Translational Neuroblastoma Research.
We focus on mechanisms that drive uncontrolled proliferation, mediate therapy resistance, block neuronal differentiation and promote the invasion-metastasis cascade by applying systems biology concepts to a solid basis of high-throughput molecular profiling data.

Preclinical neuroblastoma models include patient-derived 3D cell cultures and xenografts in mice. All research projects are directed towards providing a basis for decision-making in the rational development of improved diagnostics and novel therapeutics for high-risk neuroblastoma patients.

Further information could be found at the Charité website of the group at the Department of Pediatrics, Division of Oncology and Hematology.