Nir Friedman | Cell-free chromatin - a non-invasive window into human disease

Dear all,

we would like to warmly invite you to the lecture of BIH Visiting Prof. Nir Friedman (Hebrew University of Jerusalem) on 26 September 2022 at 2pm speaking about “Cell-free chromatin - a non-invasive window into human disease”. The lecture is followed by a small reception to connect to the speaker.

Nir Friedman has received the BIH Visiting Professorship in 2022 and is hosted by Nikolaus Rajewsky at the Berlin Institute for Medical Systems Biology.

Prof. Nir Friedman is a professor at the School of Computer Science and Engineering and the Alexander Silberman Institute of Life Sciences at Hebrew University of Jerusalem. Nir was one of the first researchers to use the Bayesian network statistical model to analyze the activation of genes. Using this model, Nir and his colleagues were able to identify groups of collectively regulated genes for the first time, along with their regulators and the conditions under which they are activated. Recently, Nir has developed a method for genome-wide assaying of circulating chromatin of cell-free nucleosomes (cfChIP-seq; Sadeh et al., Nat Biotechnol 2021). Using circulating chromatin to interrogate transcriptional states opens the way to bridge the gap between non-invasive liquid biopsies and the large and fast-growing data about gene expression patterns in tissue and cells in tissues and cells in different conditions.