News

The details of many immune defense mechanisms are still unknown, but a new study sheds light on one such mechanism. Writing in “The EMBO Journal”, researchers led by Oliver Daumke and Misha Kudryashev of the Max Delbrück Center describe exactly how GBP1 proteins render bacteria harmless by encapsulating them.

On January 29th, the European Animal Research Association (EARA) and Charité –Universitätsmedizin Berlin, in collaboration with the Max Delbrück Center and Freie Universität Berlin, invite those working in the life science sector to discuss the need for greater transparency in animal research.

The international BioRescue consortium in Berlin has announced that for the first time a rhino has successfully become pregnant following embryo transfer. This paves the way for using of the same method of reproductive medicine to save the northern white rhino from extinction.

Animal testing remains a central element in the development of medicines to ensure their safety and efficacy, despite the development of alternative research methods. Why is this the case and what alternatives are there? An interview with detektor.fm.

A team led by Charité – Universitätsmedizin Berlin, German Rheumatology Research Center and the Max Delbrück Center have defined key cells behind severe kidney damage in lupus. The research, published in “Nature,” can inform future antibody therapies.

Melissa Birol of the Max Delbrück Center is looking to understand early stages of Alzheimer’s disease. Her focus is on the interplay between the lipid metabolism of nerve cells and the spread of tau protein. The Alzheimer Research Initiative is funding her work with 193,500 euros.

This month's recommended reading comes from Russ Hodge, a science writer and trainer in the People & Culture department at the Max Delbrück Center. His tip is a gripping novel about music, family, and identity. It is set in post-war America during the civil rights movement.

Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus Rajewsky from the Max Delbrück Center now report in “Science Immunology.”

A new computer program allows scientists to design synthetic DNA segments that indicate, in real time, the state of cells. Reported by the Gargiulo lab in “Nature Communications”, it will be used to screen for anti-cancer or viral infections drugs, or to improve gene and cell-based immunotherapies.