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To answer this question, MDC scientists looked into which genes are active in thousands of old and young heart cells. They found that the heart loses its high level of organization in old age – and that connective tissue cells in particular end up getting out of control. Science December 16, 2019 How circular DNA causes cancer in children Cancer develops when DNA defects gradually accumulate over time. Thus, it is considered an age-related disease. But why do children develop tumors? An international team now reveals that rings of DNA can contribute to neuroblastoma in children. The study in Nature Genetics presents the first detailed map of circular DNA. Science December 10, 2019 The simplicity behind complexity 50 years ago today, on December 10, 1969, a reserved and modest man accepted the Nobel Prize for Medicine in Stockholm. This man was Max Delbrück, a native of Berlin. An article by Detlev Ganten. Press Release No. 58 December 02, 2019 Berlin Deep learning identifies molecular patterns of cancer An artificial intelligence platform developed at the Max Delbrück Center for Molecular Medicine (MDC) can analyze genomic data extremely quickly, picking out key patterns to classify different types of colorectal tumors and improve the drug discovery process. The deeper analysis shows some colorectal subtypes need to be reclassified. Science October 28, 2019 The art of DNA folding Ana Pombo wants to understand the rules that govern our genome. This quest has led her to discover how important our genetic architecture is for the functioning of life. In the long term, she hopes her research will help understand diseases with complex origin such as autism and epilepsy. Press Release No. 46 October 15, 2019 Berlin Gene mutation in the chloride channel triggers rare high blood pressure syndrome When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel. Researchers led by Professor Thomas Jentsch have now been able to show for the first time how the altered channels cause the disease. Their results are reported in the journal Nature Communications. Institute & Campus October 01, 2019 MDC hosts three outstanding researchers In the coming years, three Einstein BIH Visiting Fellows will collaborate closely with researchers at the Max Delbrück Center. Funding for the groups led by David Gutmann and Mario Nicodemi has been extended. New on board is Chris Sander from Harvard Medical School. Science September 10, 2019 The link between gut bacteria and blood pressure A new research group led by Dr. Nicola Wilck is investigating the influence of the gut microbiome on high blood pressure. The European Research Council (ERC) is funding the project with an ERC Starting Grant of €1.5 million over five years. Institute & Campus August 05, 2019 Friedrich Luft receives honorary doctorate from FAU Salt and blood are the two substances to which he has dedicated his research career: Professor Friedrich C. Luft, who heads a lab at the Max Delbrück Center for Molecular Medicine (MDC), has been conferred an honorary doctorate by the Faculty of Medicine of Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU). Science July 25, 2019 How the heart and gut are connected How exactly does gut bacteria affect our health? This is what the Swedish bioinformatician Sofia Forslund is trying to figure out. She also wants to develop a software that helps keep people from getting sick. 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Science December 17, 2019 How the heart ages What happens deep inside the heart as it ages? To answer this question, MDC scientists looked into which genes are active in thousands of old and young heart cells. They found that the heart loses its high level of organization in old age – and that connective tissue cells in particular end up getting out of control.
Science December 16, 2019 How circular DNA causes cancer in children Cancer develops when DNA defects gradually accumulate over time. Thus, it is considered an age-related disease. But why do children develop tumors? An international team now reveals that rings of DNA can contribute to neuroblastoma in children. The study in Nature Genetics presents the first detailed map of circular DNA.
Science December 10, 2019 The simplicity behind complexity 50 years ago today, on December 10, 1969, a reserved and modest man accepted the Nobel Prize for Medicine in Stockholm. This man was Max Delbrück, a native of Berlin. An article by Detlev Ganten.
Press Release No. 58 December 02, 2019 Berlin Deep learning identifies molecular patterns of cancer An artificial intelligence platform developed at the Max Delbrück Center for Molecular Medicine (MDC) can analyze genomic data extremely quickly, picking out key patterns to classify different types of colorectal tumors and improve the drug discovery process. The deeper analysis shows some colorectal subtypes need to be reclassified.
Science October 28, 2019 The art of DNA folding Ana Pombo wants to understand the rules that govern our genome. This quest has led her to discover how important our genetic architecture is for the functioning of life. In the long term, she hopes her research will help understand diseases with complex origin such as autism and epilepsy.
Press Release No. 46 October 15, 2019 Berlin Gene mutation in the chloride channel triggers rare high blood pressure syndrome When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel. Researchers led by Professor Thomas Jentsch have now been able to show for the first time how the altered channels cause the disease. Their results are reported in the journal Nature Communications.
Institute & Campus October 01, 2019 MDC hosts three outstanding researchers In the coming years, three Einstein BIH Visiting Fellows will collaborate closely with researchers at the Max Delbrück Center. Funding for the groups led by David Gutmann and Mario Nicodemi has been extended. New on board is Chris Sander from Harvard Medical School.
Science September 10, 2019 The link between gut bacteria and blood pressure A new research group led by Dr. Nicola Wilck is investigating the influence of the gut microbiome on high blood pressure. The European Research Council (ERC) is funding the project with an ERC Starting Grant of €1.5 million over five years.
Institute & Campus August 05, 2019 Friedrich Luft receives honorary doctorate from FAU Salt and blood are the two substances to which he has dedicated his research career: Professor Friedrich C. Luft, who heads a lab at the Max Delbrück Center for Molecular Medicine (MDC), has been conferred an honorary doctorate by the Faculty of Medicine of Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU).
Science July 25, 2019 How the heart and gut are connected How exactly does gut bacteria affect our health? This is what the Swedish bioinformatician Sofia Forslund is trying to figure out. She also wants to develop a software that helps keep people from getting sick.