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A guide to naming eukaryotic circular RNAs

Authors

  • L.L. Chen
  • A. Bindereif
  • I. Bozzoni
  • H.Y. Chang
  • A.G. Matera
  • M. Gorospe
  • T.B. Hansen
  • J. Kjems
  • X.K. Ma
  • J.W. Pek
  • N. Rajewsky
  • J. Salzman
  • J.E. Wilusz
  • L. Yang
  • F. Zhao

Journal

  • Nature Cell Biology

Citation

  • Nat Cell Biol 25 (1): 1-5

Abstract

  • Alternative splicing of eukaryotic messenger RNA transcripts often leads to the production of several mature RNAs - including linear RNAs and circular RNAs (circRNAs) - from a single gene locus. The names given to circRNAs are often ambiguous and lack consistency across studies. This Comment calls on the community to embrace a common nomenclature for naming circRNAs to ensure clarity and reproducibility.


DOI

doi:10.1038/s41556-022-01066-9