Header Serotonin

Serotonin 20 Years After

Two discoveries in 2003 fundamentally changed our understanding of the serotonin system:

  1. Tryptophan hydroxylase 2 (TPH2), as second and brain-specific serotonin synthesizing enzyme besides TPH1 in the periphery, establishing the duality of the serotonin system
  2. Serotonylation, the protein modification by covalent serotonin binding, establishing a novel pathway of serotonin signalling besides its receptors.

This meeting will present and discuss the latest news on serotonin signalling and functions in the brain and in the periphery gained after these discoveries.

Registration deadlines: 11.04.2023 (early) | 01.06.2023 (late)

Deadline of Abstract Submission: 11.04.2023

Registration Fees


Early bird


Late fee


Scientist 200 € 290 €
Student 80 € 120 €
Industry 400 € 500 €

The conference fee includes admission to all sessions, posters and exhibition; coffee breaks and lunch on both conference days and dinner on 30.06.23.


Robert-Rössle-Straße 10
13125 Berlin





Friday, June 30th


09:00 – 10:40 Session 1 Development of central serotonergic system

Susan Dymecki
Harvard Medical School, Boston, USA
Embracing differences: heterogeneity in the brain serotonergic neuronal system

Massimo Pasqualetti
University of Pisa, Italy
Development and plasticity of the serotonergic circuitry

Patricia Gaspar
Brain & Spine Institute, Sorbonne, Paris, France

Serotonin absorbing neurons: where, when, and what for?

Sharon Kolk
Radboud University, Nijmegen, The Netherlands

BEYOND a neurotransmitter; the central role of serotonin during neurodevelopment

Coffee Break

11:00 – 12:40 Session 2 Serotonin and synaptic modulation

Trevor Sharp
University of Oxford, UK

Neurobiological effects of SSRI discontinuation

Christian Lüscher
University of Geneva, Switzerland

Serotonin modulation of the transition to cocaine compulsion

Anne Roumier
INSERM UMR-S1270, Université Paris Descartes, Paris, France
5-HT2B receptor, a regulator of serotonergic neurons and of microglial cells

Alberto Bacci
Brain & Spine Institute, Sorbonne, Paris, France
Prefrontal cortical circuit dynamics in adult mice subject to early-life insult

Lunch and Posters

14:00 – 15:40 Session 3 Depression and serotonin

Klaus-Peter Lesch
University Clinic Würzburg, Germany
Cadherin-13 pleiotropy: Serotonin and beyond

Hanan El Marroun
Erasmus Medical Center Rotterdam, The Netherlands

Maternal antidepressant use, depressive symptoms and offspring development in a population-based study.

Vibe Frokjaer
Copenhagen University Hospital, Denmark
Serotonergic risk and resilience mechanisms in major depression

Coffee Break

16:00 – 17:00 Session 4 Serotonylation

Michael Bader
Max-Delbrück-Center, Berlin, Germany
Mechanisms and consequences of serotonylation as novel posttranslational protein modification

Ian Maze
Icahn School of Medicine at Mount Sinai, New York, USA
Protein monoaminylation in the brain: novel mechanisms of neural development, plasticity and disease

14:00-17:40 Key Note Lecture

Kjell Fuxe
Karolinska Institutet, Stockholm, Sweden
My personal journey through the history of serotonin

17:40 - 19:00 Poster Session



Saturday, July 1st


09:00 – 10:40 Session 5 "Environmental sensitivity and serotonin"

Judith Homberg
Radboud University, Nijmegen, The Netherlands
Your perception is not mine: the role of serotonin in individual differences in environmental sensitivity

Cornelius Gross
EMBL, Monterotondo, Italy

In pursuit of anxiety and fear: from serotonin to subordination

Markus Wöhr
KU Leuven, Belgium
Affective Communication in Rodents: Serotonin and its modulating Role in Ultrasonic Vocalizations

Coffee Break

11:00 – 12:40 Session 6 "Interaction of central and peripheral serotonin"

Anne Andrews
University of California, Los Angeles, USA
Do maternal SSRIs promote resilience or susceptibility to stress in offspring?

Natalia Alenina
Max-Delbrück-Center, Berlin, Germany
Central and peripheral TPH deficiency: impact on metabolic regulation

Francine Coté
Université Paris Descartes, Paris, France
From TPH1 to TPH2, 20 years of stimulating research

Lunch and Posters

14:00 – 15:40 Session 7 "Pharmacology of central and peripheral serotonin"

Jan Haavik

University of Bergen, Norway
Tryptophan hydroxylases as therapeutic targets

Edgar Specker / Radoslaw Wesolowski
FMP Berlin / TRYPTO Therapeutics, Berlin, Germany
Novel xanthine-based tryptophan hydroxylase inhibitors

Daniel Hoyer
University of Melbourne, Australia
Serotonin, mood and post-traumatic stress disorders: current issues

End of meeting


Additional Information



Natalia Alenina (Max Delbrück Center, Berlin)

Anne Andrews (University of California, Los Angeles)

Alberto Bacci (Brain & Spine Institute, Sorbonne, Paris)

Michael Bader (Max Delbrück Center, Berlin)

Francine Coté (Université Paris Descartes, Paris)

Susan Dymecki (Harvard Medical School, Boston)

Hanan El Marroun (Erasmus Medical Center Rotterdam)

Vibe Frokjaer (Copenhagen University Hospital)

Kjell Fuxe (Karolinska Institutet, Stockholm)

Patricia Gaspar (Brain & Spine Institute, Sorbonne, Paris )

Cornelius Gross (EMBL, Monterotondo)

Jan Haavik (University of Bergen)

Judith Homberg (Radboud University, Nijmegen)

Daniel Hoyer (University of Melbourne)

Sharon Kolk (Radboud University, Nijmegen)

Klaus-Peter Lesch (University Clinic Würzburg)

Christian Lüscher (University of Geneva)

Ian Maze (Icahn School of Medicine at Mount Sinai, New York)

Massimo Pasqualetti (University of Pisa)

Anne Roumier (Institut du Fer à Moulin, Sorbonne Université, Paris)

Trevor Sharp (University of Oxford)

Edgar Specker / Radoslaw Wesolowski (FMP Berlin / TRYPTO Therapeutics, Berlin, Germany)

Markus Wöhr (KU Leuven)

Hotel contingent


We have reserved a limited number of rooms from 27th June to 01st July 2023 in the following hotels.
You may book your room by quoting “Serotonin270623
Deadline: 30th May, 2023
Hotel Albrechtshof Berlin
Room/night: 134,- Euro (inkl. breakfast)
Albrechtstrasse 8
10117 Berlin
Hotel Allegra Berlin
Room/night: 124,- Euro (inkl. breakfast)
Albrechstrasse 17
10117 Berlin


Sponsoring options

Possibilities of support

Exclusive possibilities to present your company and support the “Serotonin 20 Years After" meeting

Platinum Support (€ 2.000)

  • Support of one prominent speaker (Your logo will be projected in the beginning of the presentation)
  • large prominent exhibition booth


  • One prominent & large exhibition booth with primary choice of the position
  • Half page advertisement on the inside or the back cover of the official online conference booklet
  • Two conference passes
  • Prominent positioning of your logo at all published conference documents and online promotion

Gold Support (€ 1.500)

  • One exhibition booth


  • One exhibition booth
  • Half page advertisement in the official online conference booklet
  • One conference pass
  • Prominent positioning of your logo on all published conference documents and online promotion

Silver Support (€ 1.000)


  • One conference pass
  • Prominent positioning of your logo on all published conference documents and online promotion

Please contact our conference office for available booth positions, inquiries and other individual possibilities of support:

MDC Events Team
Email: events@mdc-berlin.de

Sponsoring options (pdf)




Max Delbrück Communications Center
Robert-Rössle-Str. 10
13125 Berlin




Scientific organizers:

Prof. Dr. Michael Bader: mbader@mdc-berlin.de
Dr. Natalia Alenina: alenina@mdc-berlin.de

Questions organization related:

MDC Events Team
Dr. Timkehet Teffera & Lien-Georgina Dettmann


Supported by