Yifan Cheng - “Single particle cryo-EM of TRPV1: from atomic structures to gating mechanism”

Yifan Cheng (University of California San Francisco and HHMI)

“Single particle cryo-EM of TRPV1: from atomic structures to gating mechanism”.

On Sept. 22nd at 4 pm in the 061 room on the group floor of BIMSB (Hannoversche Str. 28). 

Internal live streaming: https://mdc-berlin.zoom.us/j/97678464023

Biosketch:

Dr. Yifan Cheng is a Professor at Department of Biochemistry and Biophysics, University of California San Francisco (UCSF) and an Investigator of Howard Hughes Medical Institute. He received his Ph.D. degree in 1991 from Institute of Physics, Chinese Academy of Sciences (CAS). From 1991 to 1996, he was a postdoctoral fellow at Department of Physics, University of Oslo (NTNF Fellow), and Max-Planck-Institut für Metallforschung (Alexander von Humboldt Fellow). In 1996, he changed his research field to structural biology, and received further training in electron cryo-microscopy (cryo-EM) from Professor Kenneth Taylor at Florida State University and Professor Yoshinori Fujiyoshi at Kyoto University. In 1999, he joined the laboratory of Professor Thomas Walz at Harvard Medical School. In 2006, he became a faculty at UCSF and stayed there ever since. He has been an HHMI Investigator since 2015.

Yifan Cheng and his group made major contributions to the methodology of single particle cryo-EM and its applications to determining structures of proteins and understanding their mechanisms of action. One of the research highlights is the structure of TRPV1 channel which his lab reported with the David Julius’s group first in 2013 followed by a series of studies untangling the gating mechanism.

Cheng lab at UCSF: https://cryoem.ucsf.edu/

Google Scholar: https://scholar.google.com/citations?user=pw0LluEAAAAJ

The room’s capacity is ˜100 people, operated as first come-first served. The talk will be followed by eating sausages and drinking beer on the rooftop.

You are welcome to share this invite to the colleagues in the area