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September 2019 / Cell Rep Efficient CRISPR/Cas9-mediated gene knockin in mouse hematopoietic stem and progenitor cells N.T. Tran T. Sommermann R. Graf J. Trombke J. Pempe K. Petsch R. Kühn K. Rajewsky V.T. Chu 02. Dezember 2020 / Mol Ther CRISPR/Cas9-mediated ELANE mutation correction in hematopoietic stem and progenitor cells to treat severe congenital neutropenia N.T. Tran R. Graf A. Wulf-Goldenberg M. Stecklum G. Strauß R. Kühn C. Kocks K. Rajewsky V.T. Chu 01. Juli 2019 / Front Genet Efficient and precise CRISPR/Cas9-mediated MECP2 modifications in human-induced pluripotent stem cells T.T.H. Le N.T. Tran T.M.L. Dao D.D. Nguyen H.D. Do T.L. Ha R. Kühn T.L. Nguyen K. Rajewsky V.T. Chu 19. Juni 2020 / STAR Protoc Protocol for efficient CRISPR/Cas9/AAV-mediated homologous recombination in mouse hematopoietic stem and progenitor cells N.T. Tran J. Trombke K. Rajewsky V.T. Chu 30. April 2019 / Front Genet Enhancement of precise gene editing by the association of Cas9 with homologous recombination factors N.T. Tran S. Bashir X. Li J. Rossius V.T. Chu K. Rajewsky R. Kühn 01. November 2016 / Proc Natl Acad Sci U S A Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line V.T. Chu R. Graf T. Wirtz T. Weber J. Favret X. Li K. Petsch N.T. Tran M.H. Sieweke C. Berek R. Kühn K. Rajewsky 03. Juni 2022 / Sci Adv Precise CRISPR/Cas-mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells N.T. Tran E. Danner X. Li R. Graf M. Lebedin K. de la Rosa R. Kühn K. Rajewsky V.T. Chu 20. April 2023 / Bio-protocol Application of a spacer-nick gene-targeting approach to repair disease-causing mutations with increased safety N.T. Tran M. Lebedin E. Danner R. Kühn K. Rajewsky V.T. Chu
24. September 2019 / Cell Rep Efficient CRISPR/Cas9-mediated gene knockin in mouse hematopoietic stem and progenitor cells N.T. Tran T. Sommermann R. Graf J. Trombke J. Pempe K. Petsch R. Kühn K. Rajewsky V.T. Chu
02. Dezember 2020 / Mol Ther CRISPR/Cas9-mediated ELANE mutation correction in hematopoietic stem and progenitor cells to treat severe congenital neutropenia N.T. Tran R. Graf A. Wulf-Goldenberg M. Stecklum G. Strauß R. Kühn C. Kocks K. Rajewsky V.T. Chu
01. Juli 2019 / Front Genet Efficient and precise CRISPR/Cas9-mediated MECP2 modifications in human-induced pluripotent stem cells T.T.H. Le N.T. Tran T.M.L. Dao D.D. Nguyen H.D. Do T.L. Ha R. Kühn T.L. Nguyen K. Rajewsky V.T. Chu
19. Juni 2020 / STAR Protoc Protocol for efficient CRISPR/Cas9/AAV-mediated homologous recombination in mouse hematopoietic stem and progenitor cells N.T. Tran J. Trombke K. Rajewsky V.T. Chu
30. April 2019 / Front Genet Enhancement of precise gene editing by the association of Cas9 with homologous recombination factors N.T. Tran S. Bashir X. Li J. Rossius V.T. Chu K. Rajewsky R. Kühn
01. November 2016 / Proc Natl Acad Sci U S A Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line V.T. Chu R. Graf T. Wirtz T. Weber J. Favret X. Li K. Petsch N.T. Tran M.H. Sieweke C. Berek R. Kühn K. Rajewsky
03. Juni 2022 / Sci Adv Precise CRISPR/Cas-mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells N.T. Tran E. Danner X. Li R. Graf M. Lebedin K. de la Rosa R. Kühn K. Rajewsky V.T. Chu
20. April 2023 / Bio-protocol Application of a spacer-nick gene-targeting approach to repair disease-causing mutations with increased safety N.T. Tran M. Lebedin E. Danner R. Kühn K. Rajewsky V.T. Chu