Veröffentlichungen | Max Delbrück Center

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Heinemann, Udo Prof. Dr.

25. April 2023 / Proc Natl Acad Sci U S A

TapA acts as specific chaperone in TasA filament formation by strand complementation

Y. Roske
F. Lindemann
A. Diehl
N. Cremer
V.A. Higman
B. Schlegel
M. Leidert
K. Driller
K. Turgay
P. Schmieder
U. Heinemann
H. Oschkinat

24. Januar 2023 / Proc Natl Acad Sci U S A

Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D

S. Petrović
Y. Roske
B. Rami
M.H.Q. Phan
D. Panakova
U. Heinemann

25. August 2022 / J Med Chem

Structure-based design of xanthine-benzimidazole derivatives as novel and potent tryptophan hydroxylase inhibitors

E. Specker
S. Matthes
R. Wesolowski
A. Schütz
M. Grohmann
N. Alenina
D. Pleimes
K. Mallow
M. Neuenschwander
A. Gogolin
M. Weise
J. Pfeifer
N. Ziebart
U. Heinemann
J.P. von Kries
M. Nazaré
M. Bader

15. Mai 2022 / J Mol Biol

An integrated pharmacological, structural, and genetic analysis of extracellular versus intracellular ROS production in neutrophils

C.D. Ellson
I. Goretti Riça
J.S. Kim
Y.M.M. Huang
D. Lim
T. Mitra
A. Hsu
E.X. Wei
C.D. Barrett
L.E. Otterbein
C.J. Hauser
M. Wahl
H. Delbrück
U. Heinemann
H. Oschkinat
C.E.A. Chang
M.B. Yaffe

14. Oktober 2021 / J Med Chem

Enhanced properties of a benzimidazole benzylpyrazole lysine demethylase inhibitor: mechanism-of-action, binding site analysis, and activity in cellular models of prostate cancer

D.M. Carter
E. Specker
P.H. Malecki
J. Przygodda
K. Dudaniec
M.S. Weiss
U. Heinemann
M. Nazaré
U. Gohlke

14. August 2021 / Med Genet

Technologies for profiling the impact of genomic variants on transcription factor binding

J. Leiz
M. Rutkiewicz
C. Birchmeier
U. Heinemann
K.M. Schmidt-Ott

02. Juni 2021 / Magn Reson

Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling

N. Kamdem
Y. Roske
D. Kovalskyy
M.O. Platonov
O. Balinskyi
A. Kreuchwig
J. Saupe
L. Fang
A. Diehl
P. Schmieder
G. Krause
J. Rademann
U. Heinemann
W. Birchmeier
H. Oschkinat

21. Mai 2021 / Nucleic Acids Res

PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases

A. Garg
Y. Roske
S. Yamada
T. Uehata
O. Takeuchi
U. Heinemann

07. Januar 2021 / Cancers

Cold-shock domains - abundance, structure, properties, and nucleic-acid binding

U. Heinemann
Y. Roske

01. Januar 2021 / J Biol Chem

Pantoea stewartii WceF is a glycan biofilm modifying enzyme with a bacteriophage tailspike-like fold

T. Irmscher
Y. Roske
I. Gayk
V. Dunsing
S. Chiantia
U. Heinemann
S. Barbirz