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Antibodies and Complement Conference

The antibody response and the complement system are major effector arms of the immune system. Both have been involved in a plethora of pathological conditions, including autoimmunity, allergy, infections and cancer. Antibodies and complement components regulate, mainly through their receptors (FcR and CR respectively) cell activation, ADCC, ADCP, CDC, CDCP, migration, survival but also, as recently described, metabolism. As the portfolio of antibody—and complement-effector function grow, high-end technological solutions are developed and novel therapeutic applications are proposed.

This 2nd conference on Antibodies & Complement will focus attention on key advances in both fields with the aim at fostering discussions between antibody experts and complement experts. Some of the critical topics to be covered include:

  • antibody & complement (novel) functions
  • human antibody repertoires
  • complement structure and subcellular localization
  • novel technologies
  • complement and antibody therapies

After the success of the first edition, this second edition of conference on Antibodies & Complement should again be a forum for leaders in the field and new investigators coming from academia, industry and research institutes to discuss where the field is going and what challenges lie ahead.

Venue

Hotel Eden Roc
Punta de Port Salvi, s/n
17220 Sant Feliu de Guíxols Girona
Spain

Time

-

Catering

Coffee breaks; lunch and dinner buffet

 

Hashtag

#AntibodiesComplement19

Hotel Eden Roc

Program

Day 1

Monday, May 20, 2019

14:00 Registration
16:30 Welcome & Introductions

Antibodies & Complement I

16:40 Michael Carroll, Harvard Medical School, Massachusetts, USA
Complement in adaptive immunity
17:20 early career
17:40 abstract - oral presentation
17:55 abstract - oral presentation
18:10 Brinda Prasad, Regeneron Pharmaceuticals, New York, USA
C1q bispecific antibodies killing bacteria and mammalian cells
19:00

Welcome Reception – Networking​

20:00 Dinner

Day 2

Tuesday, May 21, 2019

Antibodies & Complement II

09:00 Janine Schuurman, Genmab, Utrecht, The Netherlands
Antibody therapeutics
09:40 early career
10:00 abstract - oral presentation
10:15 abstract - oral presentation
10:30 Coffee break
11:00 Heidi Ling, Imperial College, London, UK
Complement in autoimmune diseases
11:40 early career
12:00 abstract - oral presentation
12:15 abstract - oral presentation
12:30 Lunch and social time
Special event for students and postdocs ‘Meet the expert lunch’
15:00 Ron Taylor, University of Virginia, USA
The mechanism of antibody-induced complement-mediated lysis of tumor cells
15:40 early career
16:00 abstract - oral presentation
16:15 Marjolein van Egmond, VU University Medical Center Amsterdam, The Netherlands
IgA therapeutic antibodies
16:55 abstract - oral presentation
17:10 abstract - oral presentation
17:30 Poster Session I
20:00 Dinner

Day 3

Wednesday, May 22, 2019

Antibodies in infectious diseases 

09:00 Davide Corti VIR, Bellinzona, Switzerland
Novel therapeutic antibodies in infectious diseases
09:40 early career
10:00 abstract - oral presentation
10:15 abstract - oral presentation
10:30 Coffee break
11:00 Tineke Cantaert, Institut Pasteur, Phnom Penh, Cambodia
Protective antibody response in dengue infections
11:40 abstract - oral presentation
11:55 abstract - oral presentation
12:10 Taia Wang, Stanford University, USA
Fucosylation on anti-dengue antibodies
12:50 Lunch and social time
18:00 Christian Busse, German Cancer Research Center, Heidelberg, Germany
Anti-malaria Abs and repertoires analysis
18:40 abstract - oral presentation
18:55 abstract - oral presentation
19:10 Florian Krammer, Icahn School of Medicine at Mount Sinai, New York, USA
Anti-influenza antibody repertorie
20:00 Dinner

Day 4

Thursday, May 23, 2019

Complement

09:00 Piet Gros Utrecht University, The Netherlands
Antibody and complement structures
09:40 early career
10:00 abstract - oral presentation
10:15 abstract - oral presentation
10:30 Coffee break
11:00 Daniel Ricklin, University Basel, Switzerland
Complement inhibitors
11:40 early career
12:00 abstract - oral presentation
12:15 abstract - oral presentation
12:30 Lunch and social time
Special event for students and postdocs ‘Meet the expert lunch’
15:00 Doryen Bubeck, Imperial College, London, UK
Cryo-EM structures of MAC
15:40 Claudia Kemper, National Institutes of Health, Bethesda, USA
Intracellular complement
16:20 early career
16:40 Franscesco Tedesco, University of Trieste, Italy
Alternative roles of C1q in cancer and migration
17:30 Poster Session II
20:00 Dinner

Day 5

Friday, May 24, 2019

 Antibody features

09:00 Sarel J. Fleishman, Weizmann Institute, Israel
Computational design of antibodies
09:40 early career
10:00 abstract - oral presentation
10:15 abstract - oral presentation
10:30 Coffee break
11:00 Andrea van Elsas, Aduro Biotech Europe, Oss, The Netherlands
Next generation antibodies
11:40 abstract - oral presentation
11:55 abstract - oral presentation
12:10 Brian Sutton, King's College London, UK
IgE, allergens, auto-antibodies and antigen recognition
12:50 Lunch and social time
18:00 Dario Neri, Philogen, Sovicille, Italy
Antibodies armed with cytokines
18:40 Brandon de Kosky, Kansas University, USA
Yeast display platform
19:20 Michel Cogné, University of Limoges, France
IgG5, the new human IgG subclass
20:00 Dinner
22:00 Social entertainment

Confirmed Speakers

  • Doryen Bubeck, Imperial College, London, UK

  • Christian Busse, German Cancer Research Center, Heidelberg, Germany

  • Tineke Cantaert, Institut Pasteur, Phnom Penh, Cambodia

  • Michael Carroll, Harvard Medical School, Massachusetts, USA

  • Michel Cogné, University of Limoges, France

  • Davide Corti, VIR, Bellinzona, Switzerland

  • Brandon de Kosky, Kansas University, USA

  • Sarel J. Fleishman, Weizmann Institute, Israel

  • Piet Gros, University Utrecht, The Netherlands

  • Claudia Kemper, National Institutes of Health, Bethesda, USA

  • Florian Krammer, Icahn School of Medicine at Mount Sinai, New York, USA

  • Heidi Ling, Imperial College, London, UK

  • Dario Neri, Philogen, Sovicille, Italy

  • Brinda Prasad, Regeneron Pharmaceuticals, New York, USA

  • Daniel Ricklin, University Basel, Switzerland

  • Janine Schuurman, Genmab, Copenhagen, Denmark

  • Brian Sutton, King´s College London, UK

  • Ron Taylor, University of Virginia, USA

  • Francesco Tedesco, University of Trieste, Italy

  • Marjolein van Egmond, VU University Medical Center Amsterdam, The Netherlands

  • Andrea van Elsas, Aduro Biotech Europe, Oss, The Netherlands

  • Taia Wang, Stanford University, USA


Registration

Registration deadline: April 22nd, 2019

  • 800 € - Scientist (single room)
  • 700 € - Scientist (double room)
  • 650 € - Student (double room, for single room register as scientist)
  • 1000 € - Industry (single room)
  • 320 € - Accompanying quest (non participation)

 

The registration fee includes:

  • 5 nights at the Eden Roc Hotel (regardless of the registration status)
  • admission to all scientific sessions and poster exhibition
  • conference materials
  • internet access
  • breakfast, lunch, dinner, coffee breaks and refreshments
  • social entertainment

Please note accompanying persons are not eligible to participate at the conference.


Abstract submission

Abstract deadline: April 4th, 2019

We invite all registered participants to submit an abstract about their research. The scientific organizing committee will review all abstracts and select the most relevant contributions for short talks or poster presentation. Abstracts can only be submitted online via the "Register now" button.


Travel grants

Travel grant deadline: April 4th, 2019

Several travel grants (€500-€650) will be awarded to selected students and postdocs. Selection will be performed by the conference organizers and session chairs.
One of our partners, The Antibody Society is offering up to 7 travel grants to both recognize the research activities of promising students / postdoctoral fellows and provide educational opportunities to them. In order to be considered for this competition, you must be a student or postdoc member of The Antibody Society. If you are not already a member, you may register here for a free student or postdoc membership.


Requirements:
1. submit an abstract
2. request financial support including a support letter from your mentor
3. register for free at The Antibody Society


Organizers

Pierre Bruhns
Institut Pasteur, Paris, France

Falk Nimmerjahn
University of Erlangen-Nuernberg, Germany

Suzan H.M. Rooijakkers
University Medical Center Utrecht,
The Netherlands

Kathrin de la Rosa
Max Delbrück Center for Molecular Medicine in the Helmholtz Association
Berlin, Germany

 

2018 edition – Abs & Complement

 

 

Contact:

Lien-Georgina Dettmann &
Timkehet Teffera

Max Delbrück Center for Molecular Medicine in the Helmholtz Association
Berlin, Germany

antibodies@mdc-berlin.de