Postdoctoral researcher (m/f/d)

The Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association is an international biomedical research center dedicated to understanding the molecular mechanisms of health and disease with the goal to devise new diagnostics and medicines. The MDC is a member of the Helmholtz Association, Germany's largest scientific organization, and offers an engaging research environment with cutting-edge research infrastructure. Currently, ~1250 employees and ~500 guest scientists work at the Berlin-Buch and Berlin-Mitte campuses. Our diverse workforce is a core strength that inspires creativity and innovation at the MDC.

The MDC is committed to improving human health through transformative biomedical research. Our goal is to pioneer discoveries for preventing, treating, and ultimately curing disease.

The MDC Proteome Dynamics Lab, headed by Prof. Dr. Matthias Selbach, uses mass spectrometry-based quantitative proteomics to study the dynamic proteome. We are interested in the dynamic proteome as the central link between the genome and the phenotype. To this end, we are studying protein synthesis and degradation, protein-protein interactions and posttranslational modifications. Recent technological breakthroughs have greatly increased the sensitivity and speed of proteomic analyses. We are taking advantage of these developments to study proteome dynamics in low input samples (including single cells) with high throughput.
We are looking for a postdoctoral researcher who is excited at the prospect of further developing and applying ultrasensitive and high-throughput proteomics to study the dynamic proteome. We offer an excellent science-driven working environment in a highly collaborative international team. We have the latest generation of mass spectrometers (Orbitrap Exploris 480, timsTOF Pro2, timsTOF SCP), pipetting robots, computer hard- and software as well as a fully equipped cell biology/biochemistry lab.

Job Description

• Use and further establish ultrasensitive high throughput proteomic methods (single cell, large scale screens)
• Combination of DIA (data independent acquisition) and SILAC (stable isotope labelling by amino acids in cell culture)
• Establishing automated sample processing workflows using pipetting robots (Opentrons OT-2)
• Collaboration with other members of the Selbach lab, other research teams at the MDC and clinical partners
• Computational analysis of proteomic data
• Presentations at scientific meetings and publications

Requirements

• High motivation to apply state-of-the-art proteomic technologies to key biomedical questions
• High level of scientific independency and ability to push research projects forward 
• Detailed knowledge in at least one relevant area of biology (e.g. cell biology, developmental biology, neurobiology) or medicine
• Experience in handling mass spectrometers (Orbitrap Exploris, timsTOF) and data analysis (e.g. R, Python) is a plus
• Attitude for accurate and reliable documentation and presentation of scientific data
• Strong communication skills and proficiency in English

We offer

• international working environment with communication in English and German
• interesting career opportunities and a range of opportunities for further qualification and training
• Compatibility of family and career certified by the workandfamily audit (“berufundfamilie audit”)
• Support for "New Berliners" through the MDC Welcome & Family Office
• On-campus health and fitness center

You also benefit from:

• A remuneration in accordance with the collective agreement for the federal public service (TVöD-Bund), including additional company pension schemes
• Flexible working hours and childcare support
• An idyllic green campus, which is easily accessible by bicycle, public transport or car
• A secure job
• Subsidy for the job ticket as well as discounts in the campus canteen
• Additional health benefits such as flu vaccination, eye test, ergonomics advice at the workplace,
• The possibility of mobile working
• Free use of Nextbike from the Buch S-Bahn station to the campus