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Chekulaeva Lab

Non-coding RNAs and Mechanisms of Cytoplasmic Gene Regulation

We are focusing on understanding the molecular mechanisms that regulate intracellular RNA localization, translation, and stability and role of RNA-binding proteins and non-coding RNAs in this process.

Check Chekulaeva lab home page to learn about our research

Publications

in Cold Spring Harb Perspect Biol

Roles of long noncoding RNAs and circular RNAs in translation

M. Chekulaeva et al.
in Nat Commun

RNA localization is a key determinant of neurite-enriched proteome

A. Zappulo et al.
in Mol Cell

Translation of circRNAs

NR. Pamudurti et al.
in Nucleic Acids Res

Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution

M. Mauri et al.
in Mol Cell

Eyes on translation

M. Chekulaeva et al.
in Lancet

Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study

V. Libri et al.
in Nat Struct Mol Biol

miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs

M. Chekulaeva et al.
in Nucleic Acids Res

The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression

M. Chekulaeva et al.
in Mol Cell Biol

Human Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodies

S. Ozgur et al.
in Curr Opin Cell Biol

Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells

M. Chekulaeva et al.

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