Wissenschaftliche Publikationen

01. Dezember 2015 / Nat Genet

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

L. Paternoster
M. Standl
J. Waage
H. Baurecht
M. Hotze
D.P. Strachan
J.A. Curtin
K. Bønnelykke
C. Tian
A. Takahashi
J. Esparza-Gordillo
A.C. Alves
J.P. Thyssen
H.T. den Dekker
M.A. Ferreira
E. Altmaier
P.M.A. Sleiman
F.L. Xiao
J.R. Gonzalez
I. Marenholz
B. Kalb
M. Pino-Yanes
C.J. Xu
L. Carstensen
M.M. Groen-Blokhuis
C. Venturini
C.E. Pennell
S.J. Barton
A.M. Levin
I. Curjuric
M. Bustamante
E. Kreiner-Møller
G.A. Lockett
J. Bacelis
S. Bunyavanich
R.A. Myers
A. Matanovic
A. Kumar
J.Y. Tung
T. Hirota
M. Kubo
W.L. McArdle
A.J. Henderson
J.P. Kemp
J. Zheng
G.D. Smith
F. Rüschendorf
A. Bauerfeind
M.A. Lee-Kirsch
A. Arnold
G. Homuth
C.O. Schmidt
E. Mangold
S. Cichon
T. Keil
E. Rodríguez
A. Peters
A. Franke
W. Lieb
N. Novak
R. Fölster-Holst
M. Horikoshi
J. Pekkanen
S. Sebert
L.L. Husemoen
N. Grarup
J.C. de Jongste
F. Rivadeneira
A. Hofman
V.W.V. Jaddoe
S.G.M.A. Pasmans
N.J. Elbert
A.G. Uitterlinden
G.B. Marks
P.J. Thompson
M.C. Matheson
C.F. Robertson
J.S. Ried
J. Li
X.B. Zuo
X.D. Zheng
X.Y. Yin
L.D. Sun
M.A. McAleer
G.M. O'Regan
C.M.R. Fahy
L.E. Campbell
M. Macek
M. Kurek
D. Hu
C. Eng
D.S. Postma
B. Feenstra
F. Geller
J.J. Hottenga
C.M. Middeldorp
P. Hysi
V. Bataille
T. Spector
C.M.T. Tiesler
E. Thiering
B. Pahukasahasram
J.J. Yang
M. Imboden
S. Huntsman
N. Vilor-Tejedor
C.L. Relton
R. Myhre
W. Nystad
A. Custovic
S.T. Weiss
D.A. Meyers
C. Söderhäll
E. Melén
C. Ober
B.A. Raby
A. Simpson
B. Jacobsson
J.W. Holloway
H. Bisgaard
J. Sunyer
N.M. Probst-Hensch
L.K. Williams
K.M. Godfrey
C.A. Wang
D.I. Boomsma
M. Melbye
G.H. Koppelman
D. Jarvis
W.H.I. McLean
A.D. Irvine
X.J. Zhang
H. Hakonarson
C. Gieger
E.G. Burchard
N.G. Martin
L. Duijts
A. Linneberg
M.R. Jarvelin
M.M. Noethen
S. Lau
N. Hübner
Y.A. Lee
M. Tamari
D.A. Hinds
D. Glass
S.J. Brown
J. Heinrich
D.M. Evans
S. Weidinger

Meta-analysis identifies seven susceptibility loci involved in the atopic march

I. Marenholz
J. Esparza-Gordillo
F. Rüschendorf
A. Bauerfeind
D.P. Strachan
B.D. Spycher
H. Baurecht
P. Margaritte-Jeannin
A. Sääf
M. Kerkhof
M. Ege
S. Baltic
M.C. Matheson
J. Li
S. Michel
W.Q. Ang
W. McArdle
A. Arnold
G. Homuth
F. Demenais
E. Bouzigon
C. Söderhäll
G. Pershagen
J.C. de Jongste
D.S. Postma
C. Braun-Fahrlaender
E. Horak
L.M. Ogorodova
V.P. Puzyrev
E.Y. Bragina
T.J. Hudson
C. Morin
D.L. Duffy
G.B. Marks
C.F. Robertson
G.W. Montgomery
B. Musk
P.J. Thompson
N.G. Martin
A. James
P. Sleiman
E. Toskala
E. Rodriguez
R. Fölster-Holst
A. Franke
W. Lieb
C. Gieger
A. Heinzmann
E. Rietschel
T. Keil
S. Cichon
M.M. Nöthen
C.E. Pennell
P.D. Sly
C.O. Schmidt
A. Matanovic
V. Schneider
M. Heinig
N. Hübner
P.G. Holt
S. Lau
M. Kabesch
S. Weidinger
H. Hakonarson
M.A.R. Ferreira
C. Laprise
M.B. Freidin
J. Genuneit
G.H. Koppelman
E. Melén
M.H. Dizier
A.J. Henderson
Y.A. Lee

A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis

H. Schaarschmidt
D. Ellinghaus
E. Rodríguez
A. Kretschmer
H. Baurecht
S. Lipinski
U. Meyer-Hoffert
J. Harder
W. Lieb
N. Novak
R. Fölster-Holst
J. Esparza-Gordillo
I. Marenholz
F. Ruschendorf
N. Hubner
E. Reischl
M. Waldenberger
C. Gieger
T. Illig
M. Kabesch
X.J. Zhang
F.L. Xiao
Y.A. Lee
A. Franke
S. Weidinger

Podocyte-specific deletion of murine CXADR does not impair podocyte development, function or stress response

C. Schell
O. Kretz
A. Bregenzer
M. Rogg
M. Helmstädter
U. Lisewski
M. Gotthardt
P.L. Tharaux
T.B. Huber
F. Grahammer

The Src Homology and Collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development

M. Mlih
L. Host
S. Martin
N. Niederhoffer
L. Monassier
J. Terrand
N. Messaddeq
M. Radke
M. Gotthardt
V. Bruban
F. Kober
M. Bernard
E. Canet-Soulas
F. Abt-Jijon
P. Boucher
R.L. Matz

Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease

A.M. Roberts
J.S. Ware
D.S. Herman
S. Schafer
J. Baksi
A.G. Bick
R.J. Buchan
R. Walsh
S. John
S. Wilkinson
F. Mazzarotto
L.E. Felkin
S. Gong
J.A.L. MacArthur
F. Cunningham
J. Flannick
S.B. Gabriel
D.M. Altshuler
P.S. Macdonald
M. Heinig
A.M. Keogh
C.S. Hayward
N.R. Banner
D.J. Pennell
D.P. O'Regan
T.R. San
A. de Marvao
T.J.W. Dawes
A. Gulati
E.J. Birks
M.H. Yacoub
M. Radke
M. Gotthardt
J.G. Wilson
C.J. O'Donnell
S.K. Prasad
P.J.R. Barton
D. Fatkin
N. Hubner
J.G. Seidman
C.E. Seidman
S.A. Cook

RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing

W. Guo
S. Schafer
M.L. Greaser
M.H. Radke
M. Liss
T. Govindarajan
H. Maatz
H. Schulz
S.E. Lincoln
A.M. Parrish
V. Dauksaite
P. Vakeel
S. Klaassen
B. Gerull
L. Thierfelder
V. Regitz-Zagrosek
T.A. Hacker
K.W. Saupe
G.W. Dec
P.T. Ellinor
C.A. MacRae
B. Spallek
R. Fischer
A. Perrot
C. Ozcelik
K. Saar
N. Hubner
M. Gotthardt

Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction

H.L. Granzier
M.H. Radke
J. Peng
D. Westermann
O.L. Nelson
K. Rost
N.M. King
Q. Yu
C. Tschoepe
M. McNabb
D.F. Larson
S. Labeit
M. Gotthardt

IL13 variants are associated with total serum IgE and early sensitization to food allergens in children with atopic dermatitis

S.E. Zitnik
F. Rueschendorf
S. Mueller
C. Sengler
Y.A. Lee
R.W. Griffioen
P. Meglio
U. Wahn
H. Witt
R. Nickel