Wissenschaftliche Publikationen | Max Delbrück Center

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23. Oktober 2024 / Oncogene

USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer

M. Reissland
O. Hartmann
S. Tauch
J.M. Bugter
C. Prieto-Garcia
C. Schulte
S. Loebbert
D. Solvie
E. Bitman-Lotan
A. Narain
A.C. Jacomin
C. Schuelein-Voelk
C.T. Fuss
N. Pahor
C. Ade
V. Buck
M. Potente
V. Li
G. Beliu
A. Wiegering
T. Grossmann
M. Eilers
E. Wolf
H. Maric
M. Rosenfeldt
M.M. Maurice
I. Dikic
P. Gallant
A. Orian
M.E. Diefenbacher

Oktober 2024 / EBioMedicine

Neural network-assisted humanisation of COVID-19 hamster transcriptomic data reveals matching severity states in human disease

V.D. Friedrich
P. Pennitz
E. Wyler
J.M. Adler
D. Postmus
K. Müller
L.G. Teixeira Alves
J. Prigann
F. Pott
D. Vladimirova
T. Hoefler
C. Goekeri
M. Landthaler
C. Goffinet
A.E. Saliba
M. Scholz
M. Witzenrath
J. Trimpert
H. Kirsten
G. Nouailles

August 2024 / Environ Int

Pathogen dynamics and discovery of novel viruses and enzymes by deep nucleic acid sequencing of wastewater

E. Wyler
C. Lauber
A. Manukyan
A. Deter
C. Quedenau
L.G. Teixeira Alves
C. Wylezich
T. Borodina
S. Seitz
J. Altmüller
M. Landthaler

01. August 2024 / NPJ Biofilms Microbiomes

Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19

M. Essex
B.L. Millet Pascual-Leone
U. Löber
M. Kuhring
B. Zhang
U. Brüning
R. Fritsche-Guenther
M. Krzanowski
F. Fiocca Vernengo
S. Brumhard
I. Röwekamp
A.A. Bielecka
T.R. Lesker
E. Wyler
M. Landthaler
A. Mantei
C. Meisel
S. Caesar
C. Thibeault
V.M. Corman
L. Marko
N. Suttorp
T. Strowig
F. Kurth
L.E. Sander
Y. Li
J.A. Kirwan
S.K. Forslund
B. Opitz

25. Juli 2024 / Front Immunol

A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants

K. Metzdorf
H. Jacobsen
Y. Kim
L.G. Teixeira Alves
U. Kulkarni
M.C. Brdovčak
J. Materljan
K. Eschke
M.Z. Chaudhry
M. Hoffmann
F. Bertoglio
M. Ruschig
M. Hust
M. Šustić
A. Krmpotić
S. Jonjić
M. Widera
S. Ciesek
S. Pöhlmann
M. Landthaler
L. Čičin-Šain

22. Juli 2024 / Nucleic Acids Res

iSuRe-HadCre is an essential tool for effective conditional genetics

I. Garcia-Gonzalez
S.F. Rocha
A. Hamidi
L. Garcia-Ortega
A. Regano
M.S. Sanchez-Muñoz
M. Lytvyn
A. Garcia-Cabero
S. Roig-Soucase
H. Schoofs
M. Castro
H. Sabata
M. Potente
M. Graupera
T. Makinen
R. Benedito

Juli 2024 / J Am Soc Nephrol

Grainyhead-like 2 deficiency and kidney cyst growth in a mouse model

Z.Y. Yurtdas
E. Kilic
P. Boor
E. Wyler
M. Landthaler
K. Jung
K.M. Schmidt-Ott

25. Juni 2024 / Cell Rep

Single-cell-resolved interspecies comparison shows a shared inflammatory axis and a dominant neutrophil-endothelial program in severe COVID-19

S. Peidli
G. Nouailles
E. Wyler
J.M. Adler
S. Kunder
A. Voß
J. Kazmierski
F. Pott
P. Pennitz
D. Postmus
L.G. Teixeira Alves
C. Goffinet
A.D. Gruber
N. Blüthgen
M. Witzenrath
J. Trimpert
M. Landthaler
S.D. Praktiknjo

24. Juni 2024 / Nucleic Acids Res

Despite the odds: formation of the SARS-CoV-2 methylation complex

A. Matsuda
J. Plewka
M. Rawski
A. Mourão
W. Zajko
T. Siebenmorgen
L. Kresik
K. Lis
A.N. Jones
M. Pachota
A. Karim
K. Hartman
S. Nirwal
R. Sonani
Y. Chykunova
I. Minia
P. Mak
M. Landthaler
M. Nowotny
G. Dubin
M. Sattler
P. Suder
G.M. Popowicz
K. Pyrć
A. Czarna

02. April 2024 / Mol Syst Biol

AI-guided pipeline for protein-protein interaction drug discovery identifies an SARS-CoV-2 inhibitor

P. Trepte
C. Secker
J. Olivet
J. Blavier
S. Kostova
S.B. Maseko
I. Minia
E. Silva Ramos
P. Cassonnet
S. Golusik
M. Zenkner
S. Beetz
M.J. Liebich
N. Scharek
A. Schutz
M. Sperling
M. Lisurek
Y. Wang
K. Spirohn
T. Hao
M.A. Calderwood
D.E. Hill
M. Landthaler
S.G. Choi
J.C. Twizere
M. Vidal
E.E. Wanker