Science / April 26, 2016 / Russell Hodge Cartoon: Stress on the protein synthesis pipeline Ribosomes live a tough life. They have to read messenger RNA and produce many copies of proteins over and over. Today, demand is high for histones: the proteins wich package DNA and consist of several different subunits. Enlarge
© David Ausserhofer, Max Delbrück Center Science April 24, 2025 Max Delbrück Center to host Helmholtz Drug Discovery meeting Top scientists and companies will meet in Berlin-Buch for the 2025 Helmholtz Drug Discovery Conference from April 28-30 to discuss RNA drugs, PROTACs, AI in drug discovery, and chemoproteomics and to form new collaborations.
Microscopic image of sprouting blood vessels in the retina of the eye. Shown in green are individual endothelial cells that are creating new vessels and forging new connections between vessels. All endothelial cell membranes are stained blue, while magenta highlights the inner membrane of these cells © Claudio Franco, Max Delbrück Center Press Release No. 8 April 24, 2025 How the heart and blood vessels influence organs The Helmholtz Institute for Translational AngioCardioScience (HI-TAC) invites attendees to its first Symposium on April 28 and 29, 2025. Researchers from around the world will meet at Heidelberg University to discuss how the heart and blood vessels communicate with the rest of the body to shape health.
The image shows that the tumor core is surrounded by multiple immune niches in an early-stage non-small cell lung cancer (NSCLC) patient. Analyses of these multicellular niches using single-cell resolution spatial transcriptomics identified several druggable targets. Inhibition of these targets could have prevented tumor progression in this patient, who instead received conventional chemotherapy and succumbed to the disease one year later. © Rajewsky Lab, Max Delbrück Center Press Release No. 7 April 22, 2025 Towards understanding tumors in 3D Researchers in Nikolaus Rajewsky’s lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor’s cellular neighborhoods in 3D and identify potential targets for personalized cancer therapy. They describe their findings in two separate papers in “Cell Systems.”
© David Ausserhofer, Max Delbrück Center Press Release No. 6 April 22, 2025 Helmholtz task force strengthens prevention research The Helmholtz Association is pooling its commitment to prevention research with the launch of the Helmholtz Health Prevention Task Force. In a strategy paper published in “Nature Medicine,“ the committee outlines initial concepts for integrating prevention more effectively into medical practice.