News

On January 1, 2021, the Berlin Institute of Health (BIH) has become the translational research unit of Charité – Universitätsmedizin Berlin and will then form – alongside the hospital and the medical faculty – Charité’s third pillar.

Colon cancer stem cells have one weak spot: the enzyme Mll1. An MDC team led by Walter Birchmeier has now shown in Nature Communications that blocking this protein prevents the development of new tumors in the body.

A muscle fiber consists of just one cell, but many nuclei. A team at the MDC led by Professor Carmen Birchmeier has now shown just how varied these nuclei are. The study, which has been published in Nature Communications, can help us better understand muscle diseases such as Duchenne muscular dystrophy.

We have known about a skin touch sensor for more than 160 years. MDC scientists now publish in Nature Neuroscience some of the first proof of its involvement in detecting tiny vibrations that help us to distinguish between a rough or a smooth surface.

PhD candidates now have the opportunity to apply for two new training programs. The EU is supporting the program for talented early-stage researchers at the MDC and other European research institutions to the tune of €4 million per network.

Enlarged ventricles in the brains of people with multiple sclerosis were previously considered a sign of tissue loss. But a team at the MDC and ECRC demonstrated that this expansion often recedes. A study published in JCI Insight now shows that the process observed in mice is transferable to humans.

When virologists become reality TV stars, biologists dream of life without illness, researchers debate organoids vs. animal testing with the general public, and biomedical scientists discuss the possibilities of AI, it can only be Berlin Science Week. This year, the MDC is holding a number of virtual events.

Berlin will become one of four new National Center for Tumor Diseases (NCT) locations in addition to Heidelberg and Dresden. This was announced today by the Federal Ministry of Education and Research, recognizing the outstanding achievements of Charité, the BIH and the MDC in advancing cancer treatment and research.

A new algorithmic approach reveals individual tumors continue to evolve and remodel their genomes, and this occurs across a broad range of tumor types. Identifying changes that benefit tumors and help them metastasize could help with future treatments. Results are published in Nature.

A team at the MDC has answered a question that has puzzled scientists for some 40 years. In the journal Cell, the group explains how cells are able to switch on completely different signaling pathways using only one signaling molecule: the nucleotide cAMP. To achieve this, the molecule is virtually imprisoned in nanometer-sized spaces.