Friedemann Paul group

Paul Lab

Clinical Neuroimmunology


Our focus is upon the improvement of the therapeutic and diagnostic possibilities for neuroimmunological diseases, especially for multiple sclerosis.

We are working on this with a translational approach; this means that we try to transfer new developments and findings from basic research directly into clinical work.

The Clinical Neuroimmunology Group is one of four working groups at the NeuroCure Clinical Research Center (NCRC).

Here you can find the press release concerning our latest results.


Group Leader

Prof. Dr. med. Friedemann Paul, Facharzt für Neurologie

Curriculum Vitae



Dr. med. Judith Bellmann-Strobl, Consultant Neurologist
Head of the Study Ambulance of the Research Group

Dr. med. Susanna Asseyer, Physician

Dr. med. Marcus D'Souza, Physician

Dr. med. Joseph Kuchling, Physician

PD Dr. Tanja Schmitz-Hübsch, Consultant Neurologist

Dr. med. Nadja Siebert, Consultant Neurologist



Dr. rer. medic. Hanna Gwendolyn Zimmermann
Team Leader Visual System Research

Claudia Chien, PhD
Team Leader Magnetic Resonance Imaging

Dr. rer. medic. Seydamirhosein Motamedi, Postdoc

Gilberto Solorza Buenrostro, M.Sc., PhD Student

Hadi Salih, M.Sc., PhD Student

Svenja Specovius, M.Sc. PhD Student

Dr. rer. medic. Lina Samira Bahr, Postdoc, Nutrition and Metabolism in Neuroimmunological Disease

Charlotte Bereuter, Optometrist
Coordinator Visual Assessment Lab@CSC/CTU



Dr. med. Alexander Brandt, Physician
Head of the Translational Neuroimaging Lab



Cynthia Kraut, Medical Technician, Radiology/ Data and Image Analysis

Claudia Messelhäuße, Study Assistant

Mirjana Mitrovic, Assistant

Susan Pikol, Medical Technician/ Data and Image Analysis

Bibiane Seeger-Schwinge, Medical Technician

Gritt Stoffels, Study Assistant, MS Nurse

Katharina Stößlein, Study Assistant

Bettina Zwingenberger, Study Assistant


Doctoral Candidates

Radina Arsenova

Noah Ayadi

Anna Chorschew

Frederike Cosima Oertel

Rebekka Rust


Visiting Scientists

PD Dr. med. Jan-Markus Dörr, MD (Neurologie, Klinik Hennigsdorf), Consultant Neurologist

Sebastian Mansow-Model, Mathematician (Motognosis, Berlin)

Karen Otte, Information Scientist (Motognosis, Berlin)

Dr. med. Jens Würfel, MD (MIAC AG, Basel, CH), Consultant Radiology

Dr. med. Athina Papadopoulou, Consultant Neurologist


Multiple sclerosis (MS) is the most frequent chronic inflammatory disease of the central nervous system and primarily affects young adults.

MS is causally based upon autoimmune processes; this means that the body's own immune system mistakes the nervous system as "foreign" and initiates an inflammation reaction, as a result of which nerve cells and axons, with their sheathing protective coating, are damaged. Many different neurological symptoms can occur. People suffering from MS can for example feel tingling sensations or numbness, receive paralyses or balance disorders, stumble more frequently or develop problems with their sight.

The course taken by MS varies greatly between individuals, and its course cannot be predicted well in individual patients. One of our fields of activity is the development and establishing of new progress and prognosis markers. These include, for example, the improvement of possibilities in the field of magnetic resonance imaging (MRI), e.g. ultra-high-field MRI and also the establishing of new imaging procedures such as optical coherence tomography (OCT).

It is not yet possible to cure MS. Progression and symptoms can, however, be positively influenced by various drug therapies and non-drug measures. Another fields of activity is the development and conducting of clinical studies with the aim of improving the therapeutic possibilities of MS. These include on the one hand clinical studies of phases I to IV, which we partly carry out in cooperation with the industry, and on the other hand new non-drug treatment approaches such as repetitive transcranial magnetic stimulation for the treatment of depressiveness and fatigue and visual restitution therapy for the improvement of persisting sight impairments after inflammation of the optic nerve.

Other diseases on which we have a research focus are Susac syndrome and neuromyelitis optica.

The Clinical Neuroimmunology group works in close cooperation with the interdisciplinary outpatient clinics of the Experimental and Clinical Research Center (ECRC). In addition to the Neuroimmunology outpatient clinic, other additional disciplines ensure state-of-the-art patient care based on the current state of knowledge.



Cooperation Partners

Here you find a selection of cooperation partners:
  • Clinic for Neurology, Charité - Universitätsmedizin Berlin
  • Experimental and Clinical Research Center Berlin, Charité – Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine (Prof. Dr. T. Niendorf, Dr. C. Infante)
  • Bernstein Center for Computational Neuroscience, Berlin (Prof. J. Haynes)
  • Clinic and Polyclinic for Neurology, University Medical Center Münster (Prof. Dr. E. Ringelstein, Dr. I. Kleffner)
  • Clinic and Polyclinic for Neurology, University Medical Center Hamburg Eppendorf (Prof. Dr. C. Heesen, Dr. S. Schippling)
  • Clinic for Neurology, Heinrich-Heine University Düsseldorf (Prof. Dr. O. Aktas, Dr. M. Ringelstein, Prof. Dr. H.-P. Hartung)
  • Neurological Clinic, Ruprecht-Karls-University, Heidelberg (Dr. S. Jarius, Prof. B. Wildemann)
  • Clinic and Polyclinic for Neurology of the University of Ulm (Prof. H. Tumani, Prof. v. Arnim)
  • Clinic and Polyclinic for Neurology, Neurological University Hospital, Carl Gustav Carus medical Center, Dresden (PD Dr. T. Ziemssen)
  • Center for Muscle and Bone Research (ZMK), Charité – Universitätsmedizin Berlin (Prof. Dr. D. Felsenberg, Dr. G. Armbrecht)
  • Neurology Department, Mayo Clinic, USA (Prof. B. Weinshenker)
  • Department of Neurosciences, Institut d’Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona Spain (Prof. Dr. P. Villoslada)
  • Department of Neurobiology, Weizman Institute of Science, Rehovot, Israel (Prof. A. Zangen)
  • Technion, Israel Institute of Technology, Haifa, Israel (Prof. Y. Moudim, Dr. S. Mandel)
  • Gfnmediber GmbH Berlin (A. Brandt)
  • Heidelberg Engineering GmbH, Heidelberg
  • Brainsway, Jerusalem, Israel 
  • Department of Neuropathology, University Medical Center Göttingen (Prof. Dr. W. Brück)
  • Clinic for Neurology, University Zürich (Dr. S. Schippling)
  • Beuth Hochschule für Technik Berlin (Beuth University for Applied Sciences) (Prof. Dr. H. Dietze)
  • Cooperation between BIH and Startup bootcamp
Friedemann Paul



Prof. Dr. Friedemann Paul


NeuroCure Clinical Research Center
Charité Campus Mitte

Tel:  +49 (0)30 450 539 705
Fax: +49 (0)30 450 539 915



Experimental and Clinical Research Center
Lindenberger Weg 80
13125 Berlin