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Redundant regulation

Authors

  • S.A. Lacadie
  • U. Ohler

Journal

  • Nature Ecology & Evolution

Citation

  • Nat Ecol Evol 2 (3): 418-419

Abstract

  • Control of gene activity through transcriptional regulatory elements is a major driving force in human evolution. A new study measures nascent transcription directly and shows that sequence, activity and three-dimensional organization of transcriptional regulatory elements all contribute to the evolution of gene activity within primate CD4(+) T cells.


DOI

doi:10.1038/s41559-018-0479-5