Repeat-element driven activation of proto-oncogenes in human malignancies
Authors
- B. Lamprecht
- C. Bonifer
- S. Mathas
Journal
- Cell Cycle
Citation
- Cell Cycle 9 (21): 4276-4281
Abstract
Recent data demonstrated that the aberrant activity of endogenous repetitive elements of the DNA in humans can drive the expression of proto-oncogenes. This article summarizes these results and gives an outlook on the impact of these findings on the pathogenesis and therapy of human cancer.