Clinical Research

The MDC aims to translate findings as quickly as possible into clinical applications. As a common structure established by the MDC and the Charité Medical Faculty in Berlin, the ECRC integrates a critical mass of committed clinician/scientists and translational researchers in the research-driven environment on the MDC Campus in Berlin-Buch and offers excellent opportunities for education in translational research and the development of clinician scientist careers. The Berlin Institute of Health also brings together the strengths of the MDC and Charité. The Institute combines translational research with an interdisciplinary systems medicine approach.

News

Article

Scientific image
Science

Fat tissue fuels gut inflammation

Researchers at the Max Delbrück Center and Charité – Universitätsmedizin Berlin show that adipose tissue amplifies gut inflammation in Crohn’s disease. The study, published in the “Journal of Clinical Investigation,” also reveals how genetic changes in immune cells may contribute to the disease.
Peanuts
Press Release No. 17 Berlin

Personalized treatment for peanut allergy

Oral immunotherapy helps many children with peanut allergy – but for some, it can also trigger severe allergic reactions. In the journal “Allergy”, a team led by Young-Ae Lee explains what might be behind these differences and how treatment could become more personalized.
Retinagefäße
Science

Preeclampsia: What tiny veins can tell us

There are few pregnancy diseases as life-threatening as preeclampsia. But the danger doesn’t end after birth: Mothers with preeclamptic pregnancies have a much higher risk of developing cardiovascular disease later in life. Kristin Kräker from the Experimental and Clinical Research Center is working on an early warning system.
Immunfärbung einer Plazenta
Institute & Campus

Research at the ECRC wins three awards

Two studies from the research team led by Dominik Müller and Ralf Dechend have been granted the American Heart Association’s Paul Dudley White International Scholar Award. One of the lead authors is also the winner of the Dr. Sabine Oberhauser Prize.
Portrait von H Bartolomaeus auf dem Campus Buch
Institute & Campus

Award for research on hypertension

Gut bacteria and their metabolites protect organs from the effects of hypertension – this was discovered by Hendrik Bartolomaeus in collaboration with four labs at the ECRC. For this achievement, the early career scientist is now being awarded the Walter Siegenthaler Medal in silver.
Neuron mit Myelinscheide
Press Release No. 28 Berlin

Low levels of a simple sugar – a new biomarker for severe MS?

Researchers from the ECRC in Berlin, together with scientists from the United States and Canada, have discovered a sugar molecule whose levels are reduced in the blood of patients with particularly severe multiple sclerosis. Their discovery could pave the way for a new therapeutic approach, the team reports in medical journal JAMA Neurology.
Anja Mähler
Science

In charge of the chambers

Many researchers would like to see the results of their work put to use in practical applications. Anja Mähler helps to make this a reality. She leads the Clinical Research Unit at the ECRC, which carries out studies to test basic research findings. We paid her a visit for our series “We at the MDC”.
Ventrikel im Gehirn
Press Release No. 51 Berlin

The ebb and flow of brain ventricles

Enlarged ventricles in the brains of people with multiple sclerosis were previously considered a sign of tissue loss. But a team at the MDC and ECRC demonstrated that this expansion often recedes. A study published in JCI Insight now shows that the process observed in mice is transferable to humans.
Nerve Bundle
Science

Possible therapy for repairing myelin in multiple sclerosis?

A simple sugar found in human breast milk and sold as an over-the-counter dietary supplement, promotes myelin repair in mouse models. It correlates with myelination levels in multiple sclerosis patients according to a new study published in JBC by scientists from University of California, Irvine and ECRC.
Sigal am Mikroskop
Science

New PI strengthens exchange between MDC and Charité

MDC welcomes a new guest PI: Dr. Michael Sigal, a clinician scientist at Charité – Universitätsmedizin Berlin who studies how stem cells contribute to gastrointestinal disorders and cancer. He is excited to partner with MDC to explore the gut’s interior lining on the single cell level.