MDC-BIMSB

Since 2008, the Berlin Institute for Medical Systems Biology (MDC-BIMSB) has expanded the research profile of the Max Delbrück Center. The researchers at MDC-BIMSB want to understand how genes regulate the lives of cells in health and disease. This requires the Institute’s research groups to break down the traditional boundaries between disciplines such as biotechnology, computational science, biochemistry, molecular biology, and clinical research.

Further informationen on MDC-BIMSB

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Bersucher*innen bei einem Vortrag beim Pride Symposium
Institute & Campus

Meeting adversity with resilience

Supporting each other and standing up for our values: Resilience is the theme of the 4th MDC Pride Symposium, hosted by our LGBTQI+ community on July 18 at MDC-BIMSB. For the first time, researchers will also take part in the Berlin Christopher Street Day parade under the Max Delbrück Center banner.
Andreas Diefenbach, Britta Siegmund, Nikolaus Rajewsky
Science

ImmunoPreCept: “We want to shake up medicine”

Where does health end and illness begin – and what happens in between? Researchers working in the ImmunoPreCept Excellence Cluster are planning to take a deep look inside our cells and answer this question. In this interview, the coordinators explain what they hope to achieve in the next seven years.
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Science

Berlin Summer Meeting: Sequencing Planet Earth

On June 19 and 20, the 2025 Berlin Institute of Systems Biology of the Max Delbrück Center Summer Meeting will explore how analyzing DNA and RNA can conserve biodiversity, ensure food security, and help detect and prevent disease.
Two people are looking at a tablet
Press Release No. 12 Berlin

AI helps people and doctors make medical decisions

Online symptom checkers often miss the mark. Can AI do better? Researchers from Altuna Akalin’s team at MDC-BIMSB put large language models to the test – evaluating their ability to guide patients and support doctors. Their study was published in “npj Digital Medicine.”
Melissa Birol
Science

The decrypter of cryptic proteins

How do disordered proteins drive neurological diseases? Dr. Melissa Birol uses advanced imaging and brain organoids to uncover the hidden functions of these mysterious proteins. She hopes to find novel ways to treat incurable diseases such as Alzheimer’s and Parkinson’s.
3D molecular reconstruction of a lung tumor
Press Release No. 7 Berlin

Towards understanding tumors in 3D

Researchers in Nikolaus Rajewsky’s lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor’s cellular neighborhoods in 3D and identify potential targets for personalized cancer therapy. They describe their findings in two separate papers in “Cell Systems.”
Girls in a lab
Science

Data science? Absolutely!

How does research actually work? What do data scientists and animal caretakers do? This year, 17 girls visited the Max Delbrück Center for Girls' Day – and five boys took part in Boys' Day.
Header Bergemann
Institute & Campus

Sibylle Bergemann photo exhibition

Since April 3, MDC-BIMSB in Berlin Mitte has been hosting an exhibition of 40 photographs by iconic photographer Sibylle Bergemann. During the opening, which was attended by her daughter Frieda and granddaughter Lily von Wild, the rooftop terrace was named in Bergemann’s honor.
scientific image
Press Release No. 5 Berlin

Inflammatory messenger fuels Alzheimer’s

Researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer’s disease. The study was published in the journal “Nature Aging.”
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Institute & Campus

“Seize the chance – it’s worth it!”

Doctoral student Philipp Roth went to New York as part of the Max Delbrück Center Exchange Program in Medical Systems Biology. In this interview, he discusses his research collaboration with a lab at NYU and how the exchange benefitted him in ways he could not have imagined.