MDC-BIMSB

Since 2008, the Berlin Institute for Medical Systems Biology (MDC-BIMSB) has expanded the research profile of the Max Delbrück Center. The researchers at MDC-BIMSB want to understand how genes regulate the lives of cells in health and disease. This requires the Institute’s research groups to break down the traditional boundaries between disciplines such as biotechnology, computational science, biochemistry, molecular biology, and clinical research.

Further informationen on MDC-BIMSB

Article

Two people are looking at a tablet
Press Release No. 12 Berlin

AI helps people and doctors make medical decisions

Online symptom checkers often miss the mark. Can AI do better? Researchers from Altuna Akalin’s team at MDC-BIMSB put large language models to the test – evaluating their ability to guide patients and support doctors. Their study was published in “npj Digital Medicine.”
Melissa Birol
Science

The decrypter of cryptic proteins

How do disordered proteins drive neurological diseases? Dr. Melissa Birol uses advanced imaging and brain organoids to uncover the hidden functions of these mysterious proteins. She hopes to find novel ways to treat incurable diseases such as Alzheimer’s and Parkinson’s.
3D molecular reconstruction of a lung tumor
Press Release No. 7 Berlin

Towards understanding tumors in 3D

Researchers in Nikolaus Rajewsky’s lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor’s cellular neighborhoods in 3D and identify potential targets for personalized cancer therapy. They describe their findings in two separate papers in “Cell Systems.”
Girls in a lab
Science

Data science? Absolutely!

How does research actually work? What do data scientists and animal caretakers do? This year, 17 girls visited the Max Delbrück Center for Girls' Day – and five boys took part in Boys' Day.
Header Bergemann
Institute & Campus

Sibylle Bergemann photo exhibition

Since April 3, MDC-BIMSB in Berlin Mitte has been hosting an exhibition of 40 photographs by iconic photographer Sibylle Bergemann. During the opening, which was attended by her daughter Frieda and granddaughter Lily von Wild, the rooftop terrace was named in Bergemann’s honor.
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Press Release No. 5 Berlin

Inflammatory messenger fuels Alzheimer’s

Researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer’s disease. The study was published in the journal “Nature Aging.”
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Institute & Campus

“Seize the chance – it’s worth it!”

Doctoral student Philipp Roth went to New York as part of the Max Delbrück Center Exchange Program in Medical Systems Biology. In this interview, he discusses his research collaboration with a lab at NYU and how the exchange benefitted him in ways he could not have imagined.
Simon Haas
Science

BBAW Prize for cancer researcher Simon Haas

Simon Haas has been awarded the Berlin-Brandenburg Academy of Sciences and Humanities (BBAW) Prize for the promotion of cancer research, sponsored by the Monika Kutzner Foundation. His outstanding research focuses on the causes and the development of new concepts for the treatment of blood cancer.
Symbolbild Highly Cited Researchers
Press Release No. 33 Berlin

Global influencers of science

Three researchers at Max Delbrück Center – Sofia Forslund, Friedemann Paul, and Nikolaus Rajewsky – are among the most Highly Cited Researchers in the world in 2024, making the list two years in a row. Germany ranks fourth of countries and regions, behind the U.S., mainland China and the U.K.
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Press Release No. 32 Berlin

Cancer risk linked to p53 in Ulcerative Colitis

Researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité – Universitätsmedizin Berlin have elucidated the role of the p53 gene in ulcerative colitis. The study, published in “Science Advances,” suggests a potential new drug target to stop disease progression to cancer.