Cancer Research

Our mission is to understand the principles of cancer development and progression and to provide the basis for improved diagnosis and treatment.

We investigate how cell growth, cell shape, cell death, genome integrity and protein homeostasis are regulated. We also work on understanding the molecular mechanisms that regulate cancerous processes in the body and how the immune system interacts with tumors.

Figure: Juliane Brümmer

Our groups cover a broad spectrum of interdisciplinary expertise, from mathematical modeling, cell biology, biochemistry, structural, developmental and stem cell biology to immunology, experimental tumor models and clinical oncology.

We place special emphasis on the translation of scientific findings into the clinics for the development of novel therapies, including drugs, gene and cell therapy approaches, and collaborate closely with clinically oriented groups at the Charité - Universitätsmedizin Berlin.



Prof. Dr. Claus Scheidereit


Research Groups

Signal Transduction in Development and Cancer

Prof. Dr. Walter Birchmeier

Molecular Immunology and Gene Therapy

Prof. Dr. Thomas Blankenstein


Clinical and Molecular Oncology

Prof. Dr. Peter Daniel


Molecular Oncology

Dr. Gaetano Gargiulo



Biology of Malignant Lymphomas

Dr. Martin Janz
(Co-Head: Dr. Stephan Mathas)


Biology of Malignant Lymphomas

Dr. Stephan Mathas
(Co-Head: Dr. Martin Janz)


Molecular Immunotherapy

Prof. Dr. Antonio Pezzutto

Immune Regulation and Cancer

Prof. Dr. Klaus Rajewsky


Translational Tumor Immunology

Dr. Armin Rehm
(Permanent Fellow)


Signal Transduction in Tumor Cells

Prof. Dr. Claus Scheidereit


Stem cell and macrophage biology

Dr. Michael Sieweke

Intracellular Proteolysis

Prof. Dr. Thomas Sommer


Molecular Cell Biology and Gene Therapy

Prof. Dr. Wolfgang Uckert