Harvard Biochemist Tom Rapoport Awarded Max Delbrück Medal in Berlin
“A cell is like a factory: one of its most important jobs
is to produce proteins. But in cellular factories, the sorting task is complicated
by the fact that proteins are used by the cell itself as well as delivered to
outside “customers”, Professor Rapoport said in his lecture following
the award ceremony. He was able to demonstrate that a channel located
within the cell membrane plays a crucial role in this process. This channel not
only carries some proteins through the membrane, but also stores others. For
several years, Professor Rapoport has been studying how the characteristic
shape of an organelle develops, focusing on the tubular system which extends
throughout the entire cell and is necessary for the transport of proteins.
Tom Rapoport was born on June 17, 1947 in Cincinnati, USA.
His parents had fled Nazi-Germany. In the fifties, his family returned to
Europe and eventually went to East Berlin. Following high school, Professor
Rapoport studied chemistry and biochemistry at Humboldt University in Berlin
and earned his PhD in 1972. He then became an investigator at the Central
Institute of the Academy of Sciences of the GDR in Berlin-Buch. In 1982, he
worked for a few months in the laboratory of Günter Blobel at Rockefeller
University, New York, USA, who in 1999 received the Nobel Prize. In 1985, Tom
Rapoport became Professor for Cell Biology and research group leader at the Central
Institute in Berlin-Buch, which, after German reunification, became the Max
Delbrück Center for Molecular Medicine (MDC) Berlin-Buch in 1992. Tom Rapoport
became research group leader at the MDC and in January 1995 he joined the
faculty of Harvard Medical School in Boston, where he was appointed as a Howard
Hughes Medical Institute (HHMI) investigator in 1997.
Professor Rapoport has received many honours and is a
member of several prestigious organizations including the German Academy of
Natural Scientists Leopoldina, the European Molecular Biology Organization
(EMBO), the American Academy of Arts and Sciences, and the National Academy of
Science. In addition, he is an External Scientific Member of the Max Planck Institute for Biophysical Chemistry
in Göttingen. Professor Rapoport has been awarded the Johannes Müller Prize for Experimental
Medicine, the Rudolf-Virchow Prize, and the Otto Warburg Medal of the Society
for Biochemistry and Molecular Biology.
Begun in 1992, the Max Delbrück Medal is given annually to
an outstanding scientist and is awarded at the “Berlin Lectures on
Molecular Medicine”. The “Berlin Lectures” are organized by the MDC, the
three Universities in Berlin, biomedical research institutions, and the
Schering Forschungsgesellschaft (Research Foundation). The MDC is a national
research laboratory of the Helmholtz Association of German Research Centres and
named after the Nobel Prize Winner Max Delbrück, a Berlin born physicist and
biologist (September 4, 1906 Berlin – March 10, 1981 Pasadena/USA).
Recipients of the Max Delbrück Medal
2005 Professor Tom
Rapoport, Harvard Medical School, Boston/USA
2004 Professor
Victor J. Dzau, Duke Universität, Durham (USA)
2003 Professor
Ronald D. G. McKay, National Institute of Neurological
Disorders and Stroke (NINDS), Bethesda,
USA
2002 Professor Roger Y. Tsien, Howard Hughes
Medical Institute (HHMI) und University of California, San Diego, La Jolla, USA
2001 Professor Eric S. Lander, Whitehead
Institute, Cambridge, USA
2000 Professor Joan Argetsinger Steitz, Yale
Universität, New Haven, USA)
1999 Professor Paul Berg, Stanford
Universität, USA (Nobel Prize in Chemistry, 1980)
1998 Professor Svante Pääbo, Max Planck
Institute for Evolutionary Anthropology, Leipzig, Germany
1997 Professor Charles Weissmann, University
of Zurich, Switzerland
1996 Professor Robert A. Weinberg, Whitehead
Institute, Cambridge, USA
1995 Professor Jean-Pierre Changeux,
Pasteur-Institut, Paris, Frankreich
1994 Professor
Sydney Brenner, Universität Cambridge, Großbritannien (Nobel Prize in
Medicine, 2002)
1993 cancelled
1992 Professor Günter Blobel, Rockefeller Universität New York, USA (Nobel
Prize in Medicine, 1999)
Prof. Tom Rapoport, Recipient of the Max Delbrück Medal 2005 (Photo: Harvard Medical School)
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