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Targeting autoimmunity with CD19-CAR T-cell therapy: efficacy and seroconversion in diffuse systemic sclerosis and rheumatoid arthritis

Authors

  • F.N. Albach
  • I. Minopoulou
  • A. Wilhelm
  • R. Biesen
  • A. Kleyer
  • E. Wiebe
  • A. Fleischmann
  • M. Frick
  • F. Damm
  • J. Gogolok
  • S. Serve
  • B.N. Locher
  • D. Borie
  • V. Casteleyn
  • E. Siegert
  • T. Dörner
  • T. Alexander
  • C. Furth
  • J. Zernicke
  • K. Movassaghi
  • M.L. Hütter-Krönke
  • E. Schrezenmeier
  • U. Schneider
  • L. Bullinger
  • G. Krönke
  • O. Penack
  • D. Simon

Journal

  • Rheumatology

Citation

  • Rheumatology 64 (6): 4075-4077

Abstract

  • RHEUMATOLOGY KEY MESSAGE: Anti-CD19 CAR T-cell therapy might represent a therapeutic option for severe SSc and concomitant RA.


DOI

doi:10.1093/rheumatology/keaf077