Pain

Helmholtz researchers have created the first detailed protein map of specific sensory neurons that trigger pain. Their study, published in “Nature Communications,” will help researchers better understand the molecular mechanisms of chronic inflammatory pain and identify new drug targets.

What does it take to turn Max Delbrück Center research into a startup? Meet Klaas Yperman, our very first Entrepreneur-in-Residence. Yperman has won a Helmholtz Enterprise grant to develop a roadmap for turning compounds discovered in the Lewin lab into a drug to treat neuropathic pain.

Berlin Science Week 2025 kicks off on November 1. The Max Delbrück Center invites science enthusiasts to talks and tours, a concert, and exhibitions highlighting our research and to join discussions on a wide range of topics.

Researchers in Gary Lewin’s lab at the Max Delbrück Center have identified an ion channel that contributes to chronic pain, suggesting a new target for pain medication. The study was published in “Brain.”

Neuroscientists Gary Lewin and James Poulet at the Max Delbrück Center for Molecular Medicine have won highly coveted and competitive ERC Advanced Grants to study pain and the neural mechanisms that underlie temperature perception.

Touch is a fundamental, yet scarcely understood, sense. Now, the team led by Gary Lewin at the Max Delbrück Center has discovered a second ion channel associated with touch perception. Elkin1 could be a target for pain therapy, the team writes in “Science”.

Special receptor cells under the skin enable us to feel pain and touch. But Schwann cells also play a key role in detecting such stimuli, researchers at the Max Delbrück Center report in “Nature Communications.” This discovery opens new avenues for pain therapy.

The UK’s Physiological Society has named Gary Lewin an Honorary Fellow. Two Nobel Prize laureates in Physiology or Medicine also received the distinction. It is the highest honor that the tradition-rich society presents to an individual.

Mixing and mingling on Hydra: For the anniversary of the Lewin Lab, leading somatic sensation experts, colleagues and students of Gary Lewin all came to a Greek island. In this interview, he talks with his former mentee Stefan Lechner about the symposium, dazzling personalities and what makes a good PI.

For his outstanding doctoral thesis on sexual communication in fruit flies, the Max Planck Society awards an Otto Hahn Medal to neuroscientist Mohammed Khallaf Ali. At the MDC, he works in the Lewin lab and is dedicated to the sensation of touch and pain in animals.