Research Highlights

Our research teams publish around 450 specialist articles every year. The MDC research highlights can be found here, presented in a comprehensible format.

Science

Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease

Polygenic diseases present challenges to researchers both in identifying those genes involved as well as in uncovering the complex relationship between gene expression and clinical phenotype.
Science

LRP2/megalin is required for patterning of the ventral telencephalon

Holoprosencephaly (HPE) is the most common developmental forebrain anomaly in humans and is caused...
Photo reproduced from The Journal of Cell Biology
Science

Plakophilin 2 is required for normal cardiac development

Plakophilin 2 (PKP2), a member of the armadillo protein family, has been shown to be an essential...