How vascular cells organize the hierarchical patterns of all our body’s blood and lymph vessels remains one of the most fascinating questions in biology. Failure to balance diameter variations within vessels or prevent aberrant connections between vessels can cause malformations with devastating medical consequences. However, options for clinical diagnosis and treatment are limited. Advances in translational vascular biomedicine are urgently needed to unravel the pathogenesis of such vascular anomalies and identify potential access points for therapeutic intervention.
Organized by the Berlin Center for Translational Vascular Biomedicine and supported by the Leducq Network of Excellence ATTRACT and the German Center for Cardiovascular Research (DZHK), partner site Berlin, this one-day symposium will provide a scientific forum for researchers and clinicians interested in basic and therapeutic aspects of vascular biomedicine. International experts will present the latest concepts, developments and technologies in vascular biology, covering topics such as cell biology, signaling, metabolism and genetics. Moreover, a poster session and get-together event will offer further opportunities for scientific exchange and collaboration. So if you are a Ph.D. student, postdoc, senior scientist or physician interested in translational vascular biomedicine, please join the symposium.
Please note that registration is free of charge but required.
Abstract deadline: 04 June 2023
Registration deadline: 15 June 2023
Max Delbrück Communication Center (H83), Axon 2
Small changes may occur closer to the event.
09:00 Welcome: Holger Gerhardt & Michael Potente
09:10 talk 1: Metabolic guidance of angiogenesis: principles and mechanisms
Michael Potente, Berlin Institute of Health at Charité, Berlin, Germany
09:55 talk 2: Mechanisms of arterio-venous malformations in mouse models of hereditary hemorrhagic telangiectasia
Anne Eichmann, Yale University, New Haven, USA
10:40 Coffee break
11:10 DZHK lecture 1: Novel single cell genetics and insights in vascular development
Rui Benedito, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain
12:10 Lunch break
12:50 Poster session
14:00 talk 3: Mechanisms and potential therapies for brain arteriovenous malformation
Paul Oh, Barrow Neurological Institute, Phoenix, USA
14:45 talk 4: Moyamoya Disease - features of a rare stenoocclusive angiopathy
Peter Vajkoczy, Charité - Universitätsmedizin Berlin, Germany
15:30 Coffee break
15:55 talk 5: Clinical and molecular genetic findings in patients with rare vascular diseases
Magdalena Danyel, Charité - Universitätsmedizin Berlin, Germany
16:55 DZHK lecture 2: Impact of PIK3CA mutations in vascular malformations
Mariona Graupera, Josep Carreras Leukaemia Research Institute, Barcelona, Spain
17:55 Conclusion of scientific session: Holger Gerhardt & Michael Potente
18:00 walk to the KBH and an open-end reception
From the city center (Berlin-Mitte)
- Follow Prenzlauer Promenade outward (which then becomes the A114) in the direction of Autobahn Prenzlau.
- Take the "Bucher Straße" exit, then turn right at the traffic light onto Hobrechtsfelder Chaussee in the direction of Buch. Continue driving straight for about 4 - 5km.
- Turn right at the next traffic lights onto Wiltbergstraße. Drive straight for about 2km. Pass under the S-Bahn. After a further 500m Wiltbergstraße bends to the right and merges with Karower Chaussee. Continue along this road for another 500m.
- Turn left onto Robert-Rössle-Straße, which will take you to Campus Berlin-Buch and the Max Delbrück Center.
Weekdays 06:30 - 19:00 max. 3hrs free parking. Additional hours are charged at 1€ per hour.
Evenings, weekends & public holidays: free
Enter by the Gatehouse on Robert-Rössle Strasse and take a ticket at the barrier. Turn right and make your way to the Max Delbrück Center car park (behind building 31). On leaving, if you need to pay for extra hours you can find payment machines (which accept coins, notes, and German EC cards) either by the Gatehouse or by the exit on Lindenberger Weg.
The Max Delbrück Center can be reached by public transport via the S-Bahn to “Berlin-Buch”, then by bus to the campus.
Getting to Berlin-Buch
S-Bahn: line S2, direction “Bernau” or “Buch”
From S-Bahn station Buch to the Max Delbrück Center
Bus: number 353, "Campus Buch"
On foot: a 15-20min walk
Taxi: costs around 6€. Taxi rank outside S-Bahn station
Journey planners by BVG and Deutsche Bahn
For full details of connections to the Max Delbrück Center
New to Berlin? New to Germany?
Download our handy guide to the public transport system in Berlin full of very practical advice to get you here (courtesy of the Rajewsky group). N.B. it hasn't been updated in a while - prices may have risen!
Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC)