Schnitt durch den Hippocampus
© Thomas Müller

C. Birchmeier Lab

Developmental Biology / Signal Transduction

Our lab focuses on functional analysis of genes important in development and stem cells, concentrating on muscle, the nervous system and endocrine organs.

We observe that many genes control both, developmental and regenerative processes in the adult. For our work, we use mouse genetics and stem cells culture, and define molecular mechanisms by genomic and proteomic technologies.

Team

 

tel: +49 30 9406 - extension

email (append @mdc-berlin.de)

Group Leader

 

 
Prof. Dr. Carmen Birchmeier

-3313

cbirch

Research Coordinator

 

 
Dr. Michael Strehle

-3313

mstrehle

Assistant

 

 
Dr. Timkehet Teffera

-3313

timkehet.teffera

Senior Scientist

 

 
Dr. Thomas Müller

-2842

thomu

Postdoctoral Fellows

 

 
Dr. Charlotte Chaimowizc

-2842, -3701

charlotte.chaimowicz
Dr. Joscha Griger

-2864, -2257

joscha.griger
Dr. Luis Rodrigo Hernandez-Miranda

-3772, -2257

luis.hernandes
Dr. Shiqi Jia

-3848, -2257

jshiqi
Dr. Ines Lahmann

-2864, -3701

ines.lahmann
Dr. Pierre-Louis Ruffault

-2864, -3359

pierre-louis.ruffault
Dr. Tatiana Zyrianova

-3848, -3701

tatiana.zyrianova

PhD Students

 

 
Jie-Shin Chen

-2864, -3701

jie-shin.chen
Madeleine Larrosa

-2864, -3701

madeleine.larrosa

Undergraduate Students and Interns

 

 
     

Technicians

 

 
Bettina Brandt (on leave)

-2257

bettina.brandt
Sven Buchert

-3359

sbuchert
Karin Gottschling

-3701

gottschling
Carola Griffel

-2257

cgriffel
Ivonne Schiffner (on leave)

-3359

ivonne.schiffner
Mandy Terne

-3359

mandy.terne

Animal Caretakers

 

 
Claudia Päseler

-4886

claudia.paeseler
Petra Stallerow

-4886

petra.stallerow

Publications

in Nat Rev Drug Discov

Defining orphan conditions in the context of the European orphan regulation: challenges and evolution

D.J. O'Connor et al.
in Cell

Mutations in disordered regions can cause disease by creating dileucine motifs

K. Meyer et al.
in EMBO J

Neuregulin 3 promotes excitatory synapse formation on hippocampal interneurons

T. Müller et al.
in Genes Dev

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells

M. Kim et al.
in Hum Mol Genet

Predominant patterns of splicing evolution on human, chimpanzee, and macaque evolutionary lineages

J. Xiong et al.
in Drug Discov Today

Establishing rarity in the context of orphan medicinal product designation in the European Union

S. Tsigkos et al.
in J Neurosci

Sustained MAPK/ERK activation in adult Schwann cells impairs nerve repair

I. Cervellini et al.
in Drug Discov Today

Nonclinical data supporting orphan medicinal product designations: lessons from rare neurological conditions

M.E. Sheean et al.
in Dev Biol

The dorsal spinal cord and hindbrain: from developmental mechanisms to functional circuits

L.R. Hernandez-Miranda et al.
in Proc Natl Acad Sci U S A

Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest

I. Espinosa-Medina et al.
Prof. Dr. Carmen Birchmeier-Kohler
Prof. Dr. Carmen Birchmeier-Kohler

Research Topics