Schnitt durch den Hippocampus
© Thomas Müller

C. Birchmeier Lab

Developmental Biology / Signal Transduction

Our lab focuses on functional analysis of genes important in development and stem cells, concentrating on muscle, the nervous system and endocrine organs.

We observe that many genes control both, developmental and regenerative processes in the adult. For our work, we use mouse genetics and stem cells culture, and define molecular mechanisms by genomic and proteomic technologies.

Team

 

tel: +49 30 9406 - extension

email (append @mdc-berlin.de)

Group Leader

 

 
Prof. Dr. Carmen Birchmeier

-3313

cbirch

Research Coordinator

 

 
Dr. Michael Strehle

-3313

mstrehle

Assistant

 

 
Dr. Timkehet Teffera

-3313

timkehet.teffera

Senior Scientist

 

 
Dr. Thomas Müller

-2842

thomu

Postdoctoral Fellows

 

 
Dr. Charlotte Chaimowicz

-2842, -3701

charlotte.chaimowicz
Dr. Minchul Kim

-2864, -3701

minchul.kim
Dr. Ines Lahmann

-2864, -3701

ines.lahmann
Dr. Pierre-Louis Ruffault

-2864, -3359

pierre-louis.ruffault
Dr. Kun Song

-2772, -3359

kun.song

PhD Students

 

 
Elias Lowenstein

-3772, -3701

elijahdavid.lowenstein
Yao Zhang

-3848, -3701

yao.zhang

Undergraduate Students and Interns

 

 
     

Technicians

 

 
Bettina Brandt

-2257

bettina.brandt
Sven Buchert

-3359

sbuchert
Carola Griffel

-2257

cgriffel
Vivian Schulz

-2257

vivian.schulz

Animal Caretakers

 

 
Claudia Päseler

-4886

claudia.paeseler
Petra Stallerow

-4886

petra.stallerow

Publications

in Diabetes

Haploinsufficiency of Insm1 impairs postnatal baseline β-cell mass

W. Tao et al.
in Proc Natl Acad Sci USA

Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice

L.R. Hernandez-Miranda et al.
in Cell

Mutations in disordered regions can cause disease by creating dileucine motifs

K. Meyer et al.
in Nat Rev Drug Discov

Defining orphan conditions in the context of the European orphan regulation: challenges and evolution

D.J. O'Connor et al.
in EMBO J

Neuregulin 3 promotes excitatory synapse formation on hippocampal interneurons

T. Müller et al.
in Genes Dev

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells

M. Kim et al.
in Hum Mol Genet

Predominant patterns of splicing evolution on human, chimpanzee, and macaque evolutionary lineages

J. Xiong et al.
in Drug Discov Today

Establishing rarity in the context of orphan medicinal product designation in the European Union

S. Tsigkos et al.
in J Neurosci

Sustained MAPK/ERK activation in adult Schwann cells impairs nerve repair

I. Cervellini et al.
in Drug Discov Today

Nonclinical data supporting orphan medicinal product designations: lessons from rare neurological conditions

M.E. Sheean et al.

News

Green sponge-like network of mouse skeletal muscle
Science By Dr. Martin Ballaschk

Muscle research moves from the Petri dish to gene therapy

The conference “Muscle Development, Regeneration and Disease 2018” took place at the MDC in late April. This event has in recent years become an increasingly important international platform for muscle research.
Press Release No. 16 Berlin

How mice babies ensure mother’s protection

Almost immediately after birth, mouse pups that are separated from their mother are able to make...
Science By Russell Hodge

A cool new method for growing better muscle

Striated muscle , which allows us to consciously move our bodies and makes up tissues such as the...
Science By Russell Hodge

How to insulate a stripped nerve

Without a sheath called myelin , electrical impulses would travel through our nervous system along...
Science By Russell Hodge

"I'm picking up good vibrations"

If you're reading this on your laptop right now, say over a Venti Latté at Starbucks, take your hand...
Science By Russell Hodge

Keeping muscle cells on hold

Many of our body’s tissues carry out self-repair by calling up stem cells, which specialize to...
Prof. Dr. Carmen Birchmeier-Kohler
Prof. Dr. Carmen Birchmeier-Kohler

Research Topics